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The map label for this gene is aroA [H]

Identifier: 66044143

GI number: 66044143

Start: 1010113

End: 1011369

Strand: Direct

Name: aroA [H]

Synonym: Psyr_0888

Alternate gene names: 66044143

Gene position: 1010113-1011369 (Clockwise)

Preceding gene: 66044142

Following gene: 66044144

Centisome position: 16.58

GC content: 64.76

Gene sequence:

>1257_bases
ATGCGACCTCAAGCCACCCTCACTGTTTTGCCTGTCGAGCGCCCGTTGGTCGGGCGTGTCAGCCCGCCGGGCTCCAAGTC
GATCACCAACCGTGCATTGTTGCTGGCCGGGCTGGCCAAAGGCACCAGCCGCCTGACCGGCGCGCTGAAGAGTGATGACA
CGCGCGTGATGTCCGAAGCCTTGCGTCTGATGGGCGTGCAGGTCGACGAGCCGGATGACAGCACCTTCGTGGTCACCAGC
AGCGGGCACTGGCAGGCGCCGCAACAGGCGCTGTTCCTCGGCAATGCCGGGACTGCGACACGCTTTCTGACCGCGGCACT
GGCCAACTTCGAAGGCGACTTCGTGGTGGATGGCGACGAATACATGCGCAAGCGCCCGATCGGCCCGTTGGTCGATGCCT
TGCAGCGCATGGGCGTGGAGGTCAGCGCACCCAGTGGTTGCCCGCCGGTGGCCATCAAGGGCAAGGGCGGTCTTGAGGCC
GGTCGTATCGAAATCGACGGCAATCTGTCCAGCCAGTATGTGTCGGCACTGCTGATGGCCGGTGCCTGTGGCAAGGGGCC
TGTGGAAGTTGCCCTGACAGGCAGCGAGATCGGCGCGCGTGGTTACCTCGACCTCACGCTGGCGGCCATGCGGGCGTTCG
GTGCCGAGGTTCAGGCCATCGGCGACGCCGCCTGGAAAGTCTCGGCTACCGGTTATCGCGCTACGGATTTCCACATCGAA
CCGGATGCCTCGGCGGCCACCTACCTTTGGGCTGCGCAGGCCCTGACCGAGGGCGCTATCGACCTGGGCGTGGCCAGCAA
CGCGTTCACTCAGCCTGATGCACTGGCCAGTCAGATCATCGCCAGCTTCCCGAACATGCCGGCCGTGATCGACGGCTCGC
AGATGCAGGACGCGATTCCCACGCTGGCCGTACTGGCCGCGTTCAATCGTCAACCGGTGCGCTTTGTCGGCATCGCCAAC
CTGCGGGTCAAGGAGTGCGACCGCATCTCGGCACTGTCCAACGGCCTGTGCGCCATCGCACCCGGCCTGGCGGTCGAAGA
GGGTGACGATCTGATCGTTACCGCCAACCCGACGCTGGCAGGCACTACGGTCGATGCCTTGATCGATACCCACTCCGACC
ATCGGATCGCCATGTGCTTTGCACTGGCGGGCCTGAAGATTGCCGGCATCCGCATTCTCGACCCTGATTGCGTCGCCAAG
ACCTACCCGGGGTACTGGGATGCGCTGGCTTCTCTGGGTGTGAGTGTTCAGCGCTGA

Upstream 100 bases:

>100_bases
CTGACCCGCGCCCGGGCTTGGCGATGAATGAAACCGGCACTGCGGGCTTGATCCCGCTCGTGCTAGGATCGCGATTTTTC
CGCTGACGCTCAGGGACATC

Downstream 100 bases:

>100_bases
TAGATCAGGTTTATCGGCTCGGGAAGCCTGTAGGATTTCGAGACATCTTTAGCTGGCAGTCTACGGTTGTAGATACTATG
TTTATACGTTGGGGTTGCAT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEALRLMGVQVDEPDDSTFVVTS
SGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDEYMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEA
GRIEIDGNLSSQYVSALLMAGACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIE
PDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIPTLAVLAAFNRQPVRFVGIAN
LRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLAGTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAK
TYPGYWDALASLGVSVQR

Sequences:

>Translated_418_residues
MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEALRLMGVQVDEPDDSTFVVTS
SGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDEYMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEA
GRIEIDGNLSSQYVSALLMAGACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIE
PDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIPTLAVLAAFNRQPVRFVGIAN
LRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLAGTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAK
TYPGYWDALASLGVSVQR
>Mature_418_residues
MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEALRLMGVQVDEPDDSTFVVTS
SGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDEYMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEA
GRIEIDGNLSSQYVSALLMAGACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIE
PDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIPTLAVLAAFNRQPVRFVGIAN
LRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLAGTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAK
TYPGYWDALASLGVSVQR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=431, Percent_Identity=35.4988399071926, Blast_Score=199, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320332, Length=452, Percent_Identity=34.070796460177, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 43546; Mature: 43546

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEA
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHEEHHHHCCHHHHHCCCCCCHHHHHHHH
LRLMGVQVDEPDDSTFVVTSSGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDE
HHHHCCEECCCCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEECCHH
YMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEAGRIEIDGNLSSQYVSALLMA
HHHHCCCCHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHH
GACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIE
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHEECCCCEEEEECCCEEEEEEEEC
PDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIP
CCCCHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHH
TLAVLAAFNRQPVRFVGIANLRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEECCCCEEECCCCEEEECCCCCC
GTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAKTYPGYWDALASLGVSVQR
CCCHHHHHCCCCCCEEEEEHHHHCCEEEEEEEECCHHHHCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPQATLTVLPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEA
CCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHEEHHHHCCHHHHHCCCCCCHHHHHHHH
LRLMGVQVDEPDDSTFVVTSSGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDE
HHHHCCEECCCCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEECCHH
YMRKRPIGPLVDALQRMGVEVSAPSGCPPVAIKGKGGLEAGRIEIDGNLSSQYVSALLMA
HHHHCCCCHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHH
GACGKGPVEVALTGSEIGARGYLDLTLAAMRAFGAEVQAIGDAAWKVSATGYRATDFHIE
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHEECCCCEEEEECCCEEEEEEEEC
PDASAATYLWAAQALTEGAIDLGVASNAFTQPDALASQIIASFPNMPAVIDGSQMQDAIP
CCCCHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHH
TLAVLAAFNRQPVRFVGIANLRVKECDRISALSNGLCAIAPGLAVEEGDDLIVTANPTLA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEECCCCEEECCCCEEEECCCCCC
GTTVDALIDTHSDHRIAMCFALAGLKIAGIRILDPDCVAKTYPGYWDALASLGVSVQR
CCCHHHHHCCCCCCEEEEEHHHHCCEEEEEEEECCHHHHCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA