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The map label for this gene is degP [C]

Identifier: 66044057

GI number: 66044057

Start: 907741

End: 908880

Strand: Direct

Name: degP [C]

Synonym: Psyr_0802

Alternate gene names: 66044057

Gene position: 907741-908880 (Clockwise)

Preceding gene: 66044056

Following gene: 66044058

Centisome position: 14.9

GC content: 61.49

Gene sequence:

>1140_bases
ATGAAGCTTCTTGCGCCAGGTGCAAACACTGCTTTAGCTAACGCCCACTGCCCCTGGAACCTGGAGAGCGGTAAGTCTTC
GGTTTTTGGTGAGTACGCAGCGGTCGCCTTGCTGGCGGTCAACGACAAGCGCCAGCCGATGGGTGATCCGGCGCTGCTGC
ATCAGGAGCAGGGCTGGATGGAGTGGAGCGGCGGCCCTCAGGACGTTGGCTGCACGTTAAGGCTGGACAGGTTGCCGACA
GGCAGTGATCGCGTGCTGCTGATGGTCTATGTCTATGCGGCCATGGGGCCGATCCGTGATATCGGCAGCCTGCACCTCAA
AGTGGATAGCGACATCGAGCACCGCCTGGACCTGCGCGATAACGGCGAAGCGGCGATCATCATCGGCGAGTTTTACCAGC
GCAATGAGCAATGGAAATTCCGCGCGCTGAGCGAAGGCTCGGCGTATGGACTGTCGGCATTCGGGCGCAAGATCGGACTG
GACGTGGATGATCGCCATCCTCGTCGTCCGTCTGGCGGATCCTCGGGTGGTCCTCGGCATGAGTCGGCGACCGGCACGGC
GTTCGTGGTCGGCCCGGCGCACGTCATGACCTGTGCGCATGTCATCGAAGACATGGGCGTGTTCTACATCACTTCACTTG
AAGGCCGTTACAAGGCCGAGCCAGTGGTCATCGACCGTCGCAATGACATCGCGCTGCTGCGCGTGCAGGGTGCGCCGCCG
TTGTCTCCGGTTACATTCCGGGACGGGCAGGGCTGTGAGCCGGGTGATACCGTAGCGGTTTTGGGCTATCCACTGGCATC
CATTTCAGGTGGCGGGTTGCAGGTGACTCAGGGCGGTATCTCCGGTCTGTTCGGCCTGCACAACGATGCCAGCCTGTTTC
AGTTCACGGCACCGATACAGCCGGGGTCCAGTGGCAGCCCGTTATTCGACAACGGTGGCGCGGTGATTGGCATGGTGACC
TCAACCGTACCGGACGGGCAAAACATGAACTTCGCCGTGAAGTCCGCATTGCTGCTGGCCTTTCTGCAGGCGTGCCGCAT
CGACGCTGCGCATGCCCGCCCGGAAAGGTCGTACACCACCACAGAAATCTCGCGCACCGCTCAGTCGTCGTTATGGCTCG
TTGAAGCCTCTCGCCAGTGA

Upstream 100 bases:

>100_bases
TATCCGCGTCAAGGCCATCACGGTCGCTGTACGGGCCTCGGTTTGATCGTGATAATAGATTTTTGCTATCACTAATCGCT
CTTATCAGGGAGGATCGGGC

Downstream 100 bases:

>100_bases
AGTCGGTGTTGCCTGCCTGATCCGCAGGCGTCAGGGGCTGCGGCCCCGTTAATCAGGAATTTATCGATGGACAGCAGCGC
AGCTTTTTCCAACCCTACAA

Product: peptidase S1, chymotrypsin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKLLAPGANTALANAHCPWNLESGKSSVFGEYAAVALLAVNDKRQPMGDPALLHQEQGWMEWSGGPQDVGCTLRLDRLPT
GSDRVLLMVYVYAAMGPIRDIGSLHLKVDSDIEHRLDLRDNGEAAIIIGEFYQRNEQWKFRALSEGSAYGLSAFGRKIGL
DVDDRHPRRPSGGSSGGPRHESATGTAFVVGPAHVMTCAHVIEDMGVFYITSLEGRYKAEPVVIDRRNDIALLRVQGAPP
LSPVTFRDGQGCEPGDTVAVLGYPLASISGGGLQVTQGGISGLFGLHNDASLFQFTAPIQPGSSGSPLFDNGGAVIGMVT
STVPDGQNMNFAVKSALLLAFLQACRIDAAHARPERSYTTTEISRTAQSSLWLVEASRQ

Sequences:

>Translated_379_residues
MKLLAPGANTALANAHCPWNLESGKSSVFGEYAAVALLAVNDKRQPMGDPALLHQEQGWMEWSGGPQDVGCTLRLDRLPT
GSDRVLLMVYVYAAMGPIRDIGSLHLKVDSDIEHRLDLRDNGEAAIIIGEFYQRNEQWKFRALSEGSAYGLSAFGRKIGL
DVDDRHPRRPSGGSSGGPRHESATGTAFVVGPAHVMTCAHVIEDMGVFYITSLEGRYKAEPVVIDRRNDIALLRVQGAPP
LSPVTFRDGQGCEPGDTVAVLGYPLASISGGGLQVTQGGISGLFGLHNDASLFQFTAPIQPGSSGSPLFDNGGAVIGMVT
STVPDGQNMNFAVKSALLLAFLQACRIDAAHARPERSYTTTEISRTAQSSLWLVEASRQ
>Mature_379_residues
MKLLAPGANTALANAHCPWNLESGKSSVFGEYAAVALLAVNDKRQPMGDPALLHQEQGWMEWSGGPQDVGCTLRLDRLPT
GSDRVLLMVYVYAAMGPIRDIGSLHLKVDSDIEHRLDLRDNGEAAIIIGEFYQRNEQWKFRALSEGSAYGLSAFGRKIGL
DVDDRHPRRPSGGSSGGPRHESATGTAFVVGPAHVMTCAHVIEDMGVFYITSLEGRYKAEPVVIDRRNDIALLRVQGAPP
LSPVTFRDGQGCEPGDTVAVLGYPLASISGGGLQVTQGGISGLFGLHNDASLFQFTAPIQPGSSGSPLFDNGGAVIGMVT
STVPDGQNMNFAVKSALLLAFLQACRIDAAHARPERSYTTTEISRTAQSSLWLVEASRQ

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=153, Percent_Identity=31.3725490196078, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40515; Mature: 40515

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLAPGANTALANAHCPWNLESGKSSVFGEYAAVALLAVNDKRQPMGDPALLHQEQGWM
CEEECCCCCCEEECCCCCCCCCCCCCHHHHCEEEEEEEEECCCCCCCCCHHHEECCCCCE
EWSGGPQDVGCTLRLDRLPTGSDRVLLMVYVYAAMGPIRDIGSLHLKVDSDIEHRLDLRD
ECCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCHHCCCEEEEEECCCHHHCCCCCC
NGEAAIIIGEFYQRNEQWKFRALSEGSAYGLSAFGRKIGLDVDDRHPRRPSGGSSGGPRH
CCCEEEEEEHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ESATGTAFVVGPAHVMTCAHVIEDMGVFYITSLEGRYKAEPVVIDRRNDIALLRVQGAPP
CCCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCC
LSPVTFRDGQGCEPGDTVAVLGYPLASISGGGLQVTQGGISGLFGLHNDASLFQFTAPIQ
CCCEEECCCCCCCCCCEEEEEECCHHHCCCCCEEEECCCCHHEEECCCCCCEEEEECCCC
PGSSGSPLFDNGGAVIGMVTSTVPDGQNMNFAVKSALLLAFLQACRIDAAHARPERSYTT
CCCCCCCEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCH
TEISRTAQSSLWLVEASRQ
HHHHHHHCCEEEEEEECCC
>Mature Secondary Structure
MKLLAPGANTALANAHCPWNLESGKSSVFGEYAAVALLAVNDKRQPMGDPALLHQEQGWM
CEEECCCCCCEEECCCCCCCCCCCCCHHHHCEEEEEEEEECCCCCCCCCHHHEECCCCCE
EWSGGPQDVGCTLRLDRLPTGSDRVLLMVYVYAAMGPIRDIGSLHLKVDSDIEHRLDLRD
ECCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCHHCCCEEEEEECCCHHHCCCCCC
NGEAAIIIGEFYQRNEQWKFRALSEGSAYGLSAFGRKIGLDVDDRHPRRPSGGSSGGPRH
CCCEEEEEEHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ESATGTAFVVGPAHVMTCAHVIEDMGVFYITSLEGRYKAEPVVIDRRNDIALLRVQGAPP
CCCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCC
LSPVTFRDGQGCEPGDTVAVLGYPLASISGGGLQVTQGGISGLFGLHNDASLFQFTAPIQ
CCCEEECCCCCCCCCCEEEEEECCHHHCCCCCEEEECCCCHHEEECCCCCCEEEEECCCC
PGSSGSPLFDNGGAVIGMVTSTVPDGQNMNFAVKSALLLAFLQACRIDAAHARPERSYTT
CCCCCCCEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCH
TEISRTAQSSLWLVEASRQ
HHHHHHHCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]