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The map label for this gene is obgE

Identifier: 66043968

GI number: 66043968

Start: 805622

End: 806845

Strand: Direct

Name: obgE

Synonym: Psyr_0703

Alternate gene names: 66043968

Gene position: 805622-806845 (Clockwise)

Preceding gene: 66043967

Following gene: 66043969

Centisome position: 13.22

GC content: 59.56

Gene sequence:

>1224_bases
ATGAAATTTGTAGATGAAGTATCCATTCGAGTAAAAGCCGGTGATGGCGGCAACGGTTGCATGAGCTTCCGTCGCGAAAA
ATTCATTGAAAACGGTGGTCCCAACGGTGGTGATGGTGGTGATGGCGGCTCGATCTTCATGGTCGCCGACGTCAATCTGA
ACACGCTGGTCGACTACCGTTACACCCGCCACTTCGACGCCGAGCGCGGCTCCAACGGTGGCAGCGCCGACTGCACCGGT
CGCAAGGGTGAAGAGCTGGTGCTGCGTGTGCCGGTCGGGACCACCATCATTGACGCCACTACTCAGGAAATCATCGGTGA
CCTGACCAAGGACGGTCAGCGCCTGATGGTGGCGCAGGGCGGCTGGCACGGTCTGGGTAACACCCGATTCAAGTCCAGTA
CCAACCGCGCTCCGCGCCAGACCACGCCGGGCAAGCCGGGTGATCAGCGTGACCTCAAGCTTGAGCTGAAAGTGTTGGCT
GACGTCGGCCTGCTGGGTCTGCCGAATGCCGGTAAGAGCACCTTCATCCGTTCGGTGTCTGCGGCCAAGCCGAAGGTTGC
CGACTATCCGTTCACCACGCTGGTGCCGAACCTGGGCGTGGTCAGTGTTGATCGCTGGAAAAGCTTTGTGGTTGCCGACA
TTCCAGGTCTGATCGAGGGTGCATCCGACGGCGCAGGCCTGGGGATTCGCTTCCTCAAGCACCTGGCGCGTACCCGTCTG
TTGCTGCACCTCGTCGATATGGCGCCGCTGGATGAAAGCAGTGCTCCGGATGCGGCTGAAGTGATCGTCAACGAGCTGGA
GAAATTCAGCCCGTCGCTGGCCGAGCGTGATCGCTGGCTGGTGCTGAACAAGTGCGATCAGATTCTCGAAGAGGAGCAGG
AAGCGCGCAAGCAGGAGATCGTCGATCGTCTGGAATGGACCGGCCCGGTTTACGTGATCTCTGCCATTGCCAAAGAAGGC
ACCGAGCAGCTGACCCGCGACATCATGCGTTACCTTGAAGAGCGCAGCCAGCGTATCGCCGAAGAGCCTGGTTACGCCGA
AGAGCTGGCCGAGCTCGATCAGCGCATCGAAGATGAAGCCCGTGCCCAATTGCAGGCACTGGACGATCAGCGTGCCCTGC
GTCGCAGCGGCGTGAAGAGCGTGCATGACATCGGTGACGATGACTGGGATGAAGAAGACGTGGACGATGAAGATGGTCCG
GAAATCATTTACGTCCGTGACTGA

Upstream 100 bases:

>100_bases
GGGGTCGCTGGTTTCTGATCGGTATCGCAACGCTCATTTTTGCAAGAGTCTTATGTAATTTATGTGGTTCTGCTCGTCCC
TGTGGCGGGAGGCGTGCGTT

Downstream 100 bases:

>100_bases
TCGCTTGAAGTAAACTTGAACGCCGCTACGATTGTTAGCGGCGTTTTTGTATCCCGAATTTGAAAATCTCTGGCTAGGGT
TGGAAGAAGATGCGCAGCAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMVADVNLNTLVDYRYTRHFDAERGSNGGSADCTG
RKGEELVLRVPVGTTIIDATTQEIIGDLTKDGQRLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKLELKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVVADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELEKFSPSLAERDRWLVLNKCDQILEEEQEARKQEIVDRLEWTGPVYVISAIAKEG
TEQLTRDIMRYLEERSQRIAEEPGYAEELAELDQRIEDEARAQLQALDDQRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD

Sequences:

>Translated_407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMVADVNLNTLVDYRYTRHFDAERGSNGGSADCTG
RKGEELVLRVPVGTTIIDATTQEIIGDLTKDGQRLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKLELKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVVADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELEKFSPSLAERDRWLVLNKCDQILEEEQEARKQEIVDRLEWTGPVYVISAIAKEG
TEQLTRDIMRYLEERSQRIAEEPGYAEELAELDQRIEDEARAQLQALDDQRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD
>Mature_407_residues
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMVADVNLNTLVDYRYTRHFDAERGSNGGSADCTG
RKGEELVLRVPVGTTIIDATTQEIIGDLTKDGQRLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKLELKVLA
DVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVVADIPGLIEGASDGAGLGIRFLKHLARTRL
LLHLVDMAPLDESSAPDAAEVIVNELEKFSPSLAERDRWLVLNKCDQILEEEQEARKQEIVDRLEWTGPVYVISAIAKEG
TEQLTRDIMRYLEERSQRIAEEPGYAEELAELDQRIEDEARAQLQALDDQRALRRSGVKSVHDIGDDDWDEEDVDDEDGP
EIIYVRD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=40.6832298136646, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI111955139, Length=357, Percent_Identity=35.5742296918768, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI111955063, Length=194, Percent_Identity=37.1134020618557, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789574, Length=367, Percent_Identity=60.2179836512262, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=330, Percent_Identity=34.2424242424242, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=30.42071197411, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=162, Percent_Identity=32.0987654320988, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=187, Percent_Identity=37.4331550802139, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129375, Length=332, Percent_Identity=39.7590361445783, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24585318, Length=293, Percent_Identity=37.2013651877133, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PSE14 (Q48NL2)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_273007.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q48NL2
- SMR:   Q48NL2
- STRING:   Q48NL2
- GeneID:   3560407
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_0715
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   PTRQAPN
- PhylomeDB:   Q48NL2
- ProtClustDB:   PRK12298
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 44806; Mature: 44806

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMVADVNLNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHH
YTRHFDAERGSNGGSADCTGRKGEELVLRVPVGTTIIDATTQEIIGDLTKDGQRLMVAQG
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEECC
GWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKLELKVLADVGLLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSVDRWKSFVVADIPGLIEGASDGAGLGIRFLKHLARTRL
HCCCCCCCCCHHHHCCCCCEEEHHHHHHEEHCCCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPLDESSAPDAAEVIVNELEKFSPSLAERDRWLVLNKCDQILEEEQEARKQEI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VDRLEWTGPVYVISAIAKEGTEQLTRDIMRYLEERSQRIAEEPGYAEELAELDQRIEDEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RAQLQALDDQRALRRSGVKSVHDIGDDDWDEEDVDDEDGPEIIYVRD
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMVADVNLNTLVDYR
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHH
YTRHFDAERGSNGGSADCTGRKGEELVLRVPVGTTIIDATTQEIIGDLTKDGQRLMVAQG
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEECC
GWHGLGNTRFKSSTNRAPRQTTPGKPGDQRDLKLELKVLADVGLLGLPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECCCCCHHHHHHHHH
AAKPKVADYPFTTLVPNLGVVSVDRWKSFVVADIPGLIEGASDGAGLGIRFLKHLARTRL
HCCCCCCCCCHHHHCCCCCEEEHHHHHHEEHCCCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPLDESSAPDAAEVIVNELEKFSPSLAERDRWLVLNKCDQILEEEQEARKQEI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHH
VDRLEWTGPVYVISAIAKEGTEQLTRDIMRYLEERSQRIAEEPGYAEELAELDQRIEDEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RAQLQALDDQRALRRSGVKSVHDIGDDDWDEEDVDDEDGPEIIYVRD
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA