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The map label for this gene is ygjG [C]

Identifier: 66043945

GI number: 66043945

Start: 768572

End: 769918

Strand: Direct

Name: ygjG [C]

Synonym: Psyr_0678

Alternate gene names: 66043945

Gene position: 768572-769918 (Clockwise)

Preceding gene: 66043935

Following gene: 66043946

Centisome position: 12.61

GC content: 60.28

Gene sequence:

>1347_bases
ATGAATATGTTCGAAGTGTCCGATGTGCCTGTCACCCGTCAGTTGAAGCTCGATGCTCACTGGATGCCCTACACCGCGAA
CCGAAATTTCCAGCGCGACCCGCGCATGGTCGTGGCCGCGCATGGCAGCTATCTGACAGACGACAAGGGACGCAAGATCT
ACGATGCACTCTCAGGTCTATGGACATGCGGTGCCGGGCACACGCGCAAGGAAATTCAGGAAGCCGTGTCCCGGCAATTG
GGCGTGCTGGATTACTCACCGGGCTTTCAGTTCGGGCACCCCCTGTCGTTCCAGCTGGCAGAACAGATTACCGACCTGAC
GCCGGGCAATCTCAACCACGTCTTCTATACCAACTCGGGTTCCGAGTGCGCGGATACGGCGGTGAAGATGGTACGCGCCT
ACTGGCGGCTGAAAGGCCAGGCGACCAAGACCAAGATGATCGGTCGGGCACGCGGCTACCACGGCGTGAATGTGGCGGGC
ACCAGCCTGGGCGGAGTGAATGGCAACCGCAAGATGTTCGGCCAGTTGATGGACGTCGACCACTTGCCGCACACCCTGCT
GGCCAGCAATGCGTACTCGAAGGGCATGCCCGAGGCGGGCGGTATCGCACTGGCTGACGAGATGCTCAAGCTGATCGAGT
TGCATGATGCGTCGAACATCGCTGCAGTGATCGTCGAACCCATGTCGGGCTCGGCCGGTGTGATCGTTCCGCCGCAAGGC
TATCTCAAGCGCCTGCGTGAGATTTGTGATCAACACAATATCCTGCTGATCTTCGATGAAGTCATCACCGGCTTCGGCCG
TACGGGCTCGATGTTTGGCGCGGACAGTTTCGGTGTCACGCCTGACCTGATGTGCATCGCCAAGCAGATCACCAATGGCG
CTATCCCCATGGGCGCGGTAATCGCCAGCAGCGAGATCTATCACACGTTCATGAACCAGCCAACGCCGGAGTACGCCGTC
GAGTTCCCTCATGGCTATACCTATTCCGCTCACCCCGTAGCGTGTGCGGCCGGGCTGGCGGCGCTTGAACTGCTGCAACG
GGAGAATCTGGTGCAGCAGGCCGCCGCAGTCGCGCCGCATTTTGAACGTGCGCTGCACGGTATCAAGGGCGCGAAAAACG
TGGTCGATATCCGCAATTACGGTCTGGCGGGTGCCATCCAGCTCGCACCGCGTGACGGCGATGCCATCGTGCGGCCCTTC
GAGGCCGGCATGAAGCTGTGGAAAGCCGGTTTCTATGTGCGCTTTGGCGGTGACACCCTGCAATTCGGGCCGACCTTCAA
CAGCCAGGCGCAGGACCTGGATCGCTTGTTCGATGCCGTCGGCGAAACCCTGAACCTGATCGACTGA

Upstream 100 bases:

>100_bases
TACCAAACCAAAGATCGTAAAAGTCGGGTTTTATGAACTTTAGCCGCGTGGCACCTTGGCTGCAATGACCGATCGTTTAG
CGCCTGCGAGGCCTGCTCCC

Downstream 100 bases:

>100_bases
TCGCGCTGGCAGGCTTTCTTCTTATATACGTGCCTTTATCGCATCGGGTGTGAGCTGACTCACGCCCGTTGCCTTTATCC
GGAGTTCTCCATGAGCAGCA

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNMFEVSDVPVTRQLKLDAHWMPYTANRNFQRDPRMVVAAHGSYLTDDKGRKIYDALSGLWTCGAGHTRKEIQEAVSRQL
GVLDYSPGFQFGHPLSFQLAEQITDLTPGNLNHVFYTNSGSECADTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNVAG
TSLGGVNGNRKMFGQLMDVDHLPHTLLASNAYSKGMPEAGGIALADEMLKLIELHDASNIAAVIVEPMSGSAGVIVPPQG
YLKRLREICDQHNILLIFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQITNGAIPMGAVIASSEIYHTFMNQPTPEYAV
EFPHGYTYSAHPVACAAGLAALELLQRENLVQQAAAVAPHFERALHGIKGAKNVVDIRNYGLAGAIQLAPRDGDAIVRPF
EAGMKLWKAGFYVRFGGDTLQFGPTFNSQAQDLDRLFDAVGETLNLID

Sequences:

>Translated_448_residues
MNMFEVSDVPVTRQLKLDAHWMPYTANRNFQRDPRMVVAAHGSYLTDDKGRKIYDALSGLWTCGAGHTRKEIQEAVSRQL
GVLDYSPGFQFGHPLSFQLAEQITDLTPGNLNHVFYTNSGSECADTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNVAG
TSLGGVNGNRKMFGQLMDVDHLPHTLLASNAYSKGMPEAGGIALADEMLKLIELHDASNIAAVIVEPMSGSAGVIVPPQG
YLKRLREICDQHNILLIFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQITNGAIPMGAVIASSEIYHTFMNQPTPEYAV
EFPHGYTYSAHPVACAAGLAALELLQRENLVQQAAAVAPHFERALHGIKGAKNVVDIRNYGLAGAIQLAPRDGDAIVRPF
EAGMKLWKAGFYVRFGGDTLQFGPTFNSQAQDLDRLFDAVGETLNLID
>Mature_448_residues
MNMFEVSDVPVTRQLKLDAHWMPYTANRNFQRDPRMVVAAHGSYLTDDKGRKIYDALSGLWTCGAGHTRKEIQEAVSRQL
GVLDYSPGFQFGHPLSFQLAEQITDLTPGNLNHVFYTNSGSECADTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNVAG
TSLGGVNGNRKMFGQLMDVDHLPHTLLASNAYSKGMPEAGGIALADEMLKLIELHDASNIAAVIVEPMSGSAGVIVPPQG
YLKRLREICDQHNILLIFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQITNGAIPMGAVIASSEIYHTFMNQPTPEYAV
EFPHGYTYSAHPVACAAGLAALELLQRENLVQQAAAVAPHFERALHGIKGAKNVVDIRNYGLAGAIQLAPRDGDAIVRPF
EAGMKLWKAGFYVRFGGDTLQFGPTFNSQAQDLDRLFDAVGETLNLID

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=443, Percent_Identity=29.1196388261851, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI13994255, Length=397, Percent_Identity=27.9596977329975, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=29.2168674698795, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI37574042, Length=372, Percent_Identity=28.494623655914, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI226442705, Length=372, Percent_Identity=28.2258064516129, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI24119277, Length=390, Percent_Identity=25.3846153846154, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226442709, Length=336, Percent_Identity=28.8690476190476, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI145693181, Length=311, Percent_Identity=35.048231511254, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786991, Length=429, Percent_Identity=29.3706293706294, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=29.2079207920792, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788044, Length=435, Percent_Identity=29.1954022988506, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=28.7153652392947, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=28.1407035175879, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786349, Length=326, Percent_Identity=28.5276073619632, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=447, Percent_Identity=28.4116331096197, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=26.3657957244656, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=378, Percent_Identity=28.8359788359788, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=229, Percent_Identity=31.8777292576419, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=252, Percent_Identity=25.7936507936508, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323470, Length=444, Percent_Identity=25.9009009009009, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324386, Length=488, Percent_Identity=24.5901639344262, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=413, Percent_Identity=23.2445520581114, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357415, Length=442, Percent_Identity=26.4705882352941, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=25.8351893095768, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574759, Length=451, Percent_Identity=26.6075388026608, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356575, Length=395, Percent_Identity=26.3291139240506, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48762; Mature: 48762

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMFEVSDVPVTRQLKLDAHWMPYTANRNFQRDPRMVVAAHGSYLTDDKGRKIYDALSGL
CCCEECCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHH
WTCGAGHTRKEIQEAVSRQLGVLDYSPGFQFGHPLSFQLAEQITDLTPGNLNHVFYTNSG
EECCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCC
SECADTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNVAGTSLGGVNGNRKMFGQLMDVD
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHC
HLPHTLLASNAYSKGMPEAGGIALADEMLKLIELHDASNIAAVIVEPMSGSAGVIVPPQG
CCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCHH
YLKRLREICDQHNILLIFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQITNGAIPMGAV
HHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
IASSEIYHTFMNQPTPEYAVEFPHGYTYSAHPVACAAGLAALELLQRENLVQQAAAVAPH
HHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERALHGIKGAKNVVDIRNYGLAGAIQLAPRDGDAIVRPFEAGMKLWKAGFYVRFGGDTL
HHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCEEEEECCCEE
QFGPTFNSQAQDLDRLFDAVGETLNLID
EECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMFEVSDVPVTRQLKLDAHWMPYTANRNFQRDPRMVVAAHGSYLTDDKGRKIYDALSGL
CCCEECCCCCCEEEEEECCCCCCEECCCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHH
WTCGAGHTRKEIQEAVSRQLGVLDYSPGFQFGHPLSFQLAEQITDLTPGNLNHVFYTNSG
EECCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCC
SECADTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNVAGTSLGGVNGNRKMFGQLMDVD
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHC
HLPHTLLASNAYSKGMPEAGGIALADEMLKLIELHDASNIAAVIVEPMSGSAGVIVPPQG
CCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCHH
YLKRLREICDQHNILLIFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQITNGAIPMGAV
HHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
IASSEIYHTFMNQPTPEYAVEFPHGYTYSAHPVACAAGLAALELLQRENLVQQAAAVAPH
HHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERALHGIKGAKNVVDIRNYGLAGAIQLAPRDGDAIVRPFEAGMKLWKAGFYVRFGGDTL
HHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCEEEEECCCEE
QFGPTFNSQAQDLDRLFDAVGETLNLID
EECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]