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The map label for this gene is waaA [H]

Identifier: 66043809

GI number: 66043809

Start: 611935

End: 613080

Strand: Direct

Name: waaA [H]

Synonym: Psyr_0542

Alternate gene names: 66043809

Gene position: 611935-613080 (Clockwise)

Preceding gene: 66043804

Following gene: 66043811

Centisome position: 10.04

GC content: 64.05

Gene sequence:

>1146_bases
ATGCAGCGGGGCGGTATCTGGGTGCATGCGGTGTCGGTGGGTGAAAGCATCGCCGCCGCGCCGATGATTCGCTCGCTGCT
GGTGCAATATCCGCAGTTGCCGATCACTGTGACTTGCATGACGCCCACAGGTTCGGAGCGAATCAAGGCGCTGTTCGCCA
GCGAGCCGCGGATTCAGCATTGCTACCTGCCCTACGACCTGCCGTGGGCGGCCGCTCGCTTTCTCGATCAGGTGCAGCCA
CGGCTGGGCATCATCATGGAAACCGAACTGTGGCCCAACCACATCCATCAGTGTTTCCTGCGCGGGATTCCCGTGGTGCT
CGCCAATGCGCGGCTGTCGGAGCGTTCGGCGCGGGGTTACGCACGCTTTGCCGGCCTGACACGACCGATGCTCGCGGAAA
TGGCCTGGTTCGCTGTGCAGACTGAAGCTGAGGCAAAGCGCTTTCGTGATCTGGGCGCACGTCCCGAGTGCGTGGCGGTG
ACCGGCTCGATCAAGTTCGACCTGAGCATCGACCCGCAACTTCTGCAGCGTGCCGCCCAGCAGCGTGAACAATGGCAGAC
CACGCAGCGGCCGGTCTGGATCGCGGCCAGCACGCATGCGGGCGAGGATGAAAGCGTGCTGGCGGCTCATCGCACGTTAC
TGACCAGTCACCCCGACGCGCTGCTGATTCTTGTGCCGCGTCATCCCGAGCGTTTCGACAGCGTGCATGCGTTGTGTCAG
CAGCAGGGTTTTGCGACGGTAAGACGCTCAACCGGGCAGGCTGTCACGGCGGATGTTTCGGTACTGATGGGCGATACCAT
GGGGGAATTGCTGTTTCTCTATGCGCTGGCTGACATCGCTTTCGTTGGCGGCAGCCTGGTGCCCAACGGCGGGCACAACC
TGCTGGAGCCTGCGGCGCTGGCCATGCCGGTGCTCAGCGGCCCGCACCTGTTCAACTTCCTCGAGATCGCCGCCATGCTG
CGCAAGGCCGGTGCGTTGCAAGAGGTCAATGATGCAGCAGCGCTGGCCACCGCCGTGCAGGGCCTTTTCGACCAGCCGCA
GCAGGCGCGCAACATGGCCGATGCCGGGCTTGCGGTGATGAAGGCCAACCAGGGCGCACTGCAACGCCTGCTCGACGGGA
TCGGGCGGTTGATGGGCAAACGCTGA

Upstream 100 bases:

>100_bases
CGGCCTGCCACTGGTTGCCCTGCGCCTTTGGTTGCGTGCGCGCAAGGCCCCTGCGTATCGCCAGCGCATTGGCGAGCGCT
TTGCCCGCGGCTTGCCGGTC

Downstream 100 bases:

>100_bases
ATCGGGAGGACGCAGAGCGTCCGGAACGGCATACCGACGCGGAGCATGGGCACGATAGTGTTCTTCCAGACACCTTGCTT
TTTTCACGCTCTTCACGCTC

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MQRGGIWVHAVSVGESIAAAPMIRSLLVQYPQLPITVTCMTPTGSERIKALFASEPRIQHCYLPYDLPWAAARFLDQVQP
RLGIIMETELWPNHIHQCFLRGIPVVLANARLSERSARGYARFAGLTRPMLAEMAWFAVQTEAEAKRFRDLGARPECVAV
TGSIKFDLSIDPQLLQRAAQQREQWQTTQRPVWIAASTHAGEDESVLAAHRTLLTSHPDALLILVPRHPERFDSVHALCQ
QQGFATVRRSTGQAVTADVSVLMGDTMGELLFLYALADIAFVGGSLVPNGGHNLLEPAALAMPVLSGPHLFNFLEIAAML
RKAGALQEVNDAAALATAVQGLFDQPQQARNMADAGLAVMKANQGALQRLLDGIGRLMGKR

Sequences:

>Translated_381_residues
MQRGGIWVHAVSVGESIAAAPMIRSLLVQYPQLPITVTCMTPTGSERIKALFASEPRIQHCYLPYDLPWAAARFLDQVQP
RLGIIMETELWPNHIHQCFLRGIPVVLANARLSERSARGYARFAGLTRPMLAEMAWFAVQTEAEAKRFRDLGARPECVAV
TGSIKFDLSIDPQLLQRAAQQREQWQTTQRPVWIAASTHAGEDESVLAAHRTLLTSHPDALLILVPRHPERFDSVHALCQ
QQGFATVRRSTGQAVTADVSVLMGDTMGELLFLYALADIAFVGGSLVPNGGHNLLEPAALAMPVLSGPHLFNFLEIAAML
RKAGALQEVNDAAALATAVQGLFDQPQQARNMADAGLAVMKANQGALQRLLDGIGRLMGKR
>Mature_381_residues
MQRGGIWVHAVSVGESIAAAPMIRSLLVQYPQLPITVTCMTPTGSERIKALFASEPRIQHCYLPYDLPWAAARFLDQVQP
RLGIIMETELWPNHIHQCFLRGIPVVLANARLSERSARGYARFAGLTRPMLAEMAWFAVQTEAEAKRFRDLGARPECVAV
TGSIKFDLSIDPQLLQRAAQQREQWQTTQRPVWIAASTHAGEDESVLAAHRTLLTSHPDALLILVPRHPERFDSVHALCQ
QQGFATVRRSTGQAVTADVSVLMGDTMGELLFLYALADIAFVGGSLVPNGGHNLLEPAALAMPVLSGPHLFNFLEIAAML
RKAGALQEVNDAAALATAVQGLFDQPQQARNMADAGLAVMKANQGALQRLLDGIGRLMGKR

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=371, Percent_Identity=52.5606469002695, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 41602; Mature: 41602

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGGIWVHAVSVGESIAAAPMIRSLLVQYPQLPITVTCMTPTGSERIKALFASEPRIQH
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCEE
CYLPYDLPWAAARFLDQVQPRLGIIMETELWPNHIHQCFLRGIPVVLANARLSERSARGY
EECCCCCCHHHHHHHHHHCCHHCEEEECCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHH
ARFAGLTRPMLAEMAWFAVQTEAEAKRFRDLGARPECVAVTGSIKFDLSIDPQLLQRAAQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHHHHHH
QREQWQTTQRPVWIAASTHAGEDESVLAAHRTLLTSHPDALLILVPRHPERFDSVHALCQ
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QQGFATVRRSTGQAVTADVSVLMGDTMGELLFLYALADIAFVGGSLVPNGGHNLLEPAAL
HCCHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHH
AMPVLSGPHLFNFLEIAAMLRKAGALQEVNDAAALATAVQGLFDQPQQARNMADAGLAVM
HHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEE
KANQGALQRLLDGIGRLMGKR
ECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRGGIWVHAVSVGESIAAAPMIRSLLVQYPQLPITVTCMTPTGSERIKALFASEPRIQH
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCEE
CYLPYDLPWAAARFLDQVQPRLGIIMETELWPNHIHQCFLRGIPVVLANARLSERSARGY
EECCCCCCHHHHHHHHHHCCHHCEEEECCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHH
ARFAGLTRPMLAEMAWFAVQTEAEAKRFRDLGARPECVAVTGSIKFDLSIDPQLLQRAAQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHHHHHH
QREQWQTTQRPVWIAASTHAGEDESVLAAHRTLLTSHPDALLILVPRHPERFDSVHALCQ
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
QQGFATVRRSTGQAVTADVSVLMGDTMGELLFLYALADIAFVGGSLVPNGGHNLLEPAAL
HCCHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCHHHH
AMPVLSGPHLFNFLEIAAMLRKAGALQEVNDAAALATAVQGLFDQPQQARNMADAGLAVM
HHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEE
KANQGALQRLLDGIGRLMGKR
ECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]