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The map label for this gene is fabD [H]

Identifier: 66043715

GI number: 66043715

Start: 484738

End: 485673

Strand: Direct

Name: fabD [H]

Synonym: Psyr_0448

Alternate gene names: 66043715

Gene position: 484738-485673 (Clockwise)

Preceding gene: 66043714

Following gene: 66043716

Centisome position: 7.95

GC content: 66.77

Gene sequence:

>936_bases
ATGAGCAGCCTGTGGGTGTTTCCCGGCCAGGGTTCGCAGCAAACCGGCATGCTGCATCAGTTGCCGGACGAGGCCGTGGT
GCGCGACTGCCTGCAGGAAGCCGCCGATGCGCTGGGCGAAGACGTGCTGGCGCTGGACACCGCCGGGGCGCTGCAAGCCA
CGCGTGCCGTTCAGCTTTGCCTGTTGATCGCGGGCGTCGCATGCGCACGCGTGCTGCAGGCGCGTGATTGTGTGCCGGAC
TACCTGGCCGGGCTGTCCATCGGTGCTTATCCGGCAGCGGTGGTTTCGGGGGCGCTGGCCTTTGACGACGCCGTGCGCCT
GGTCGCGTTGCGTGGCGAGCTGATGCAAAGCGCCTGGCCGCAGGGTTACGGCATGACCGCGCTCATCGGCCTGGACCAGA
CACAGGTAGAAGCGCTGATCGGGCAGGTACACAGCGCGAAGACACCGGTATTTCTCGCCAATATCAACGCCGACAACCAG
ATGGTGATCTCCGGCAGTGCCGAGGCGATGCATCAGGTCGGTCAGTTGGCCAAGGCTGCCGGAGCGGCAGCGGTCAAGCG
TCTTGCGGTCAGCGTACCGTCACATTGCGCCTTGCTGGACGCTCCCGCGCAACAACTGGCCGAGGCCTTTTCAAGGGTCG
CGCTGCAGGCACCCACGCTACGTTACCTCAGCGGCAGCACGGCGCGGCCGGTGCTGAGTGCCGAGAAGCTGCGTGACGAC
CTGGCCTTCAACATGTGCCGGGTCATCGACTGGCGCAGCACCGTGGAAACCGCCTGGGAGCGGGGCGTGCGCCTGCACAT
CGAATTGCCGCCCGGCAGTGTGCTGACCGGGCTGGCACGCAAAGTATTCCAGCAGGGCAGCGCGCTGGCTTTTCAGGCTG
CGCGCCTGGACAGCCTGGTCGCGCTGTCGCGCGAGGAGGGTCGCCGCACCCCATAG

Upstream 100 bases:

>100_bases
CGCTGCGTGAGTGGGCGCGGCCAACGGGGCGGGTGCTGCTCAAGACCGCCACCGGCGCGCGGCTGGTTGCAGACCCGTGG
CACCTGGGTCAGGTGTGCGC

Downstream 100 bases:

>100_bases
AGCCGCCGTGCAGCTGCTACGAAGGACAAAAACAACAACTTCAGCAATGCAAACAGAGGAATAACAACAATGATTATCTA
CGGTGTTGCACTACTGGCCA

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSSLWVFPGQGSQQTGMLHQLPDEAVVRDCLQEAADALGEDVLALDTAGALQATRAVQLCLLIAGVACARVLQARDCVPD
YLAGLSIGAYPAAVVSGALAFDDAVRLVALRGELMQSAWPQGYGMTALIGLDQTQVEALIGQVHSAKTPVFLANINADNQ
MVISGSAEAMHQVGQLAKAAGAAAVKRLAVSVPSHCALLDAPAQQLAEAFSRVALQAPTLRYLSGSTARPVLSAEKLRDD
LAFNMCRVIDWRSTVETAWERGVRLHIELPPGSVLTGLARKVFQQGSALAFQAARLDSLVALSREEGRRTP

Sequences:

>Translated_311_residues
MSSLWVFPGQGSQQTGMLHQLPDEAVVRDCLQEAADALGEDVLALDTAGALQATRAVQLCLLIAGVACARVLQARDCVPD
YLAGLSIGAYPAAVVSGALAFDDAVRLVALRGELMQSAWPQGYGMTALIGLDQTQVEALIGQVHSAKTPVFLANINADNQ
MVISGSAEAMHQVGQLAKAAGAAAVKRLAVSVPSHCALLDAPAQQLAEAFSRVALQAPTLRYLSGSTARPVLSAEKLRDD
LAFNMCRVIDWRSTVETAWERGVRLHIELPPGSVLTGLARKVFQQGSALAFQAARLDSLVALSREEGRRTP
>Mature_310_residues
SSLWVFPGQGSQQTGMLHQLPDEAVVRDCLQEAADALGEDVLALDTAGALQATRAVQLCLLIAGVACARVLQARDCVPDY
LAGLSIGAYPAAVVSGALAFDDAVRLVALRGELMQSAWPQGYGMTALIGLDQTQVEALIGQVHSAKTPVFLANINADNQM
VISGSAEAMHQVGQLAKAAGAAAVKRLAVSVPSHCALLDAPAQQLAEAFSRVALQAPTLRYLSGSTARPVLSAEKLRDDL
AFNMCRVIDWRSTVETAWERGVRLHIELPPGSVLTGLARKVFQQGSALAFQAARLDSLVALSREEGRRTP

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=26.6447368421053, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787334, Length=299, Percent_Identity=39.4648829431438, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71984332, Length=245, Percent_Identity=28.1632653061224, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=23.3676975945017, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665753, Length=314, Percent_Identity=29.9363057324841, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32846; Mature: 32715

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLWVFPGQGSQQTGMLHQLPDEAVVRDCLQEAADALGEDVLALDTAGALQATRAVQLC
CCCEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LLIAGVACARVLQARDCVPDYLAGLSIGAYPAAVVSGALAFDDAVRLVALRGELMQSAWP
HHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGYGMTALIGLDQTQVEALIGQVHSAKTPVFLANINADNQMVISGSAEAMHQVGQLAKAA
CCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
GAAAVKRLAVSVPSHCALLDAPAQQLAEAFSRVALQAPTLRYLSGSTARPVLSAEKLRDD
HHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHH
LAFNMCRVIDWRSTVETAWERGVRLHIELPPGSVLTGLARKVFQQGSALAFQAARLDSLV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ALSREEGRRTP
HHHHHCCCCCC
>Mature Secondary Structure 
SSLWVFPGQGSQQTGMLHQLPDEAVVRDCLQEAADALGEDVLALDTAGALQATRAVQLC
CCEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LLIAGVACARVLQARDCVPDYLAGLSIGAYPAAVVSGALAFDDAVRLVALRGELMQSAWP
HHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGYGMTALIGLDQTQVEALIGQVHSAKTPVFLANINADNQMVISGSAEAMHQVGQLAKAA
CCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
GAAAVKRLAVSVPSHCALLDAPAQQLAEAFSRVALQAPTLRYLSGSTARPVLSAEKLRDD
HHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHH
LAFNMCRVIDWRSTVETAWERGVRLHIELPPGSVLTGLARKVFQQGSALAFQAARLDSLV
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ALSREEGRRTP
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]