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The map label for this gene is accD [C]

Identifier: 66043712

GI number: 66043712

Start: 482458

End: 483309

Strand: Direct

Name: accD [C]

Synonym: Psyr_0445

Alternate gene names: 66043712

Gene position: 482458-483309 (Clockwise)

Preceding gene: 66043711

Following gene: 66043713

Centisome position: 7.92

GC content: 63.38

Gene sequence:

>852_bases
ATGACTGATAACGCACGGTTGCTGAATCAGCACAGTTTCATCGAACTGGGTGCCCGACAGCGCGCCCGTGCCTTGCTGGA
TGCCGGCAGTTTCCGCGAACTGCTCGGTCCGTTCGATCGGGTCATGTCGCCGTGGCTGGCCATGCAGGGCGTGGTGCCTC
AGGCGGATGATGGCGTGGTGGTCGGCAAAGGCACTGTCGATGGTCGGCCAGTGGTCATCGCCGCCATCGAAGGTTCTTTT
CAGGGCGGCAGCATGGGCGAAGTCGGCGGTGCGAAGATGGCCGGTGCGCTGGAACTGGCCGCCGAAGACAACCGCAACGG
CATTCCTACCGCCGCGATCGTGCTGCTGGAAACCGGTGGCGTGCGTTTGCAGGAAGCCAATCTGGGCCTGGCCGCGATTG
CCGAGATTCATGCCGCGATAGTCGACCTGCGTCAGTACCAGCCGGTGATCGGTGTGGTGGCCGGCAGCGTCGGCTGCTTT
GGCGGGATGTCCATCGCCGCAGGGCTGTGCAGTTACCTGCTGGTGACTCAGGAAGCACGTCTGGGCCTGAACGGTCCGCA
GGTGATCGAGCAGGAAGCCGGCATCGAAGAATACGACTCCCGCGACCGTCCGTTCATCTGGAGCCTGACCGGTGGCGAGC
AACGCTTTGCCAGCGCGCTGGTGGATGGTTTTGCTGCCGATGATGTCGCCGATGTGCGCCAGCAGGTCAGCGGCTGGCTC
AAGCAGGGCGTGCCCGACACGCATCGCAGCAGTCAGTACCCACTGTTCCTGCAACGTCTGGCCAGCCTCGACACTGAACC
GCAAATCGATCCGCAAAGCGTGCGCACCCTCTATCAAGGAGCCCGGTCATGA

Upstream 100 bases:

>100_bases
GGCCAGACCCCGCCTGCGCTGAGCATCGATATTCATGACTTCGGCGCGACGCCCGGCGTTGTGCGTATGCGCCTGGAGCA
AGGCTTCGAGGAGATCGGTC

Downstream 100 bases:

>100_bases
GTCATTCACAACGGGGTTTGAACTGGTTCAACGCCTTGAGCGCAGGTGCCCGTGAAGTCACTGGCCTGCCTGCCTCACTC
AAGGTGGCGGATGGCGTGCT

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: Transcarboxylase 12S subunit [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTDNARLLNQHSFIELGARQRARALLDAGSFRELLGPFDRVMSPWLAMQGVVPQADDGVVVGKGTVDGRPVVIAAIEGSF
QGGSMGEVGGAKMAGALELAAEDNRNGIPTAAIVLLETGGVRLQEANLGLAAIAEIHAAIVDLRQYQPVIGVVAGSVGCF
GGMSIAAGLCSYLLVTQEARLGLNGPQVIEQEAGIEEYDSRDRPFIWSLTGGEQRFASALVDGFAADDVADVRQQVSGWL
KQGVPDTHRSSQYPLFLQRLASLDTEPQIDPQSVRTLYQGARS

Sequences:

>Translated_283_residues
MTDNARLLNQHSFIELGARQRARALLDAGSFRELLGPFDRVMSPWLAMQGVVPQADDGVVVGKGTVDGRPVVIAAIEGSF
QGGSMGEVGGAKMAGALELAAEDNRNGIPTAAIVLLETGGVRLQEANLGLAAIAEIHAAIVDLRQYQPVIGVVAGSVGCF
GGMSIAAGLCSYLLVTQEARLGLNGPQVIEQEAGIEEYDSRDRPFIWSLTGGEQRFASALVDGFAADDVADVRQQVSGWL
KQGVPDTHRSSQYPLFLQRLASLDTEPQIDPQSVRTLYQGARS
>Mature_282_residues
TDNARLLNQHSFIELGARQRARALLDAGSFRELLGPFDRVMSPWLAMQGVVPQADDGVVVGKGTVDGRPVVIAAIEGSFQ
GGSMGEVGGAKMAGALELAAEDNRNGIPTAAIVLLETGGVRLQEANLGLAAIAEIHAAIVDLRQYQPVIGVVAGSVGCFG
GMSIAAGLCSYLLVTQEARLGLNGPQVIEQEAGIEEYDSRDRPFIWSLTGGEQRFASALVDGFAADDVADVRQQVSGWLK
QGVPDTHRSSQYPLFLQRLASLDTEPQIDPQSVRTLYQGARS

Specific function: The 12S subunit specifically catalyzes the transfer of the carboxyl group of methylmalonyl CoA to the biotin of the 1.3S subunit forming propanoyl-CoA and carboxylated 1.3S-biotin [H]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=197, Percent_Identity=35.0253807106599, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 30000; Mature: 29869

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNARLLNQHSFIELGARQRARALLDAGSFRELLGPFDRVMSPWLAMQGVVPQADDGVV
CCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VGKGTVDGRPVVIAAIEGSFQGGSMGEVGGAKMAGALELAAEDNRNGIPTAAIVLLETGG
EECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEECCC
VRLQEANLGLAAIAEIHAAIVDLRQYQPVIGVVAGSVGCFGGMSIAAGLCSYLLVTQEAR
CEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLNGPQVIEQEAGIEEYDSRDRPFIWSLTGGEQRFASALVDGFAADDVADVRQQVSGWL
CCCCCHHHHHHHCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KQGVPDTHRSSQYPLFLQRLASLDTEPQIDPQSVRTLYQGARS
HHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TDNARLLNQHSFIELGARQRARALLDAGSFRELLGPFDRVMSPWLAMQGVVPQADDGVV
CCCCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VGKGTVDGRPVVIAAIEGSFQGGSMGEVGGAKMAGALELAAEDNRNGIPTAAIVLLETGG
EECCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEECCC
VRLQEANLGLAAIAEIHAAIVDLRQYQPVIGVVAGSVGCFGGMSIAAGLCSYLLVTQEAR
CEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLNGPQVIEQEAGIEEYDSRDRPFIWSLTGGEQRFASALVDGFAADDVADVRQQVSGWL
CCCCCHHHHHHHCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KQGVPDTHRSSQYPLFLQRLASLDTEPQIDPQSVRTLYQGARS
HHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366018 [H]