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The map label for this gene is pepC [H]

Identifier: 62390381

GI number: 62390381

Start: 1580913

End: 1582175

Strand: Reverse

Name: pepC [H]

Synonym: cg1693

Alternate gene names: 62390381

Gene position: 1582175-1580913 (Counterclockwise)

Preceding gene: 62390384

Following gene: 62390380

Centisome position: 48.2

GC content: 55.27

Gene sequence:

>1263_bases
ATGCATGTAACTGACGATTTCTTAAGTTTTATTGCCCTAAGCCCAAGTTCCTATCACGCGGCCGCGGCGGTGGAGCGCAG
GTTGCTCCATGAGGGGTTCATTCGTCAGGAAGATACCGATGAATGGGATGCCCGCCCTGGTGGGCATGTGACGGTGCGTG
GGGGAGCAGTAGTGGCGTGGTGGGTGCCTGAGGATGCTTCGCCAGATTCCGGGTTCCGCATCATTGGGTCACATACTGAT
TCACCGGGTTTCAAGTTAAAGCCCCGTGGGGATCTTTCCTCACACGGTTGGCAGCAGGCCGGCGTCGAGGTTTACGGCGG
ACCGATCCTGCCAAGCTGGCTGGATCGCGAGCTGGCCTTAGCAGGCCGCATTGTGCTTGCCGACGGGTCCGTCAAGCTTG
TCAACACCGGCCCGATTCTGCGCATCCCGCACGTGGCTATTCATTTGGACCGTACTGTTAATTCCCAACTCACCCTTAAT
CCACAGCGTCACCTGCAGCCTGTGTTTGCTGTTGGTGAGCCCGACGTATCAATTCTGGATGTCATTGCTGGTGCTGCGGT
AGTGGATCCTGCAGATATTGTCAGCCATGATCTGATCACGGTGGCTACCCAAGATGCTGAAGTATTTGGCGCACATGGGG
ATTTCTTGGCGTCTGGTCGCCTGGATAACCTGAGCAGCGTGCATCCATCCATGACTGCATTGATTGCGGCTTCGCAATCT
GACGATACTGGTTCGGATATTTTGGTTCTTGCTGCATTCGATCATGAAGAAGTGGGAAGTAATTCCACCTCGGGTGCCGG
GGGCCCCCTGTTGGAGGATGTGCTCAACCGTACTGCTCGTGCGTTGGGTGCAGATGAAGATGAGCGACGCCGGATGTTTA
ACCGTTCCACCATGGTCTCAGCTGACGCGGCACACTCCATTCACCCCAACTTCCCCGAGAAGCATGATCAAGCTAATTAC
CCCATCATTGGTAAAGGTCCTGTATTGAAGGTCAACGCCAACCAGCGCTACACCTCCGATGCAGTCACTTCAGGCATGTG
GATCAGGGCATGTCAGATTGCCGGTGTGCCACACCAGGTGTTTGCCGGCAACAACGATGTGCCGTGTGGTTCCACCATCG
GCCCGATCAGTGCGACTCGCCTGGGTATCGATTCTGTCGATGTCGGTATTCCATTGCTGTCCATGCACTCCGCACGCGAA
ATGGCCGGAGTGAAGGATCTGATGTGGTTTGAACAAGCCCTGGAAGCCTATCTGGTAAATTAA

Upstream 100 bases:

>100_bases
ATAATGATCACCTACTTTAACGGCTTCAGGTGACATTGTGGATTCGCATTGTGGATTCGGGGGCCCGCGCTGTTTCCAAG
AATTTGGCTACCCTTGTTCT

Downstream 100 bases:

>100_bases
CGCCGAGTTCAATCAAGACAAGCACACAGAAGAAAGTGAGGGCTCATGCCCTACTCAGGTCCGTTCCAAGCAGGCGACCG
CGTTCAGCTCACCGACGCTA

Product: aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVAWWVPEDASPDSGFRIIGSHTD
SPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQLTLN
PQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASGRLDNLSSVHPSMTALIAASQS
DDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMVSADAAHSIHPNFPEKHDQANY
PIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSARE
MAGVKDLMWFEQALEAYLVN

Sequences:

>Translated_420_residues
MHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVAWWVPEDASPDSGFRIIGSHTD
SPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQLTLN
PQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASGRLDNLSSVHPSMTALIAASQS
DDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMVSADAAHSIHPNFPEKHDQANY
PIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSARE
MAGVKDLMWFEQALEAYLVN
>Mature_420_residues
MHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVAWWVPEDASPDSGFRIIGSHTD
SPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELALAGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQLTLN
PQRHLQPVFAVGEPDVSILDVIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASGRLDNLSSVHPSMTALIAASQS
DDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMVSADAAHSIHPNFPEKHDQANY
PIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQVFAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSARE
MAGVKDLMWFEQALEAYLVN

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=448, Percent_Identity=37.5, Blast_Score=284, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17552916, Length=430, Percent_Identity=34.8837209302326, Blast_Score=232, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6321905, Length=461, Percent_Identity=35.3579175704989, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322746, Length=441, Percent_Identity=26.984126984127, Blast_Score=162, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 44901; Mature: 44901

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVAW
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEE
WVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELAL
ECCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHHCCEEEECCCCCHHHHCCHHHH
AGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQLTLNPQRHLQPVFAVGEPDVSILD
CCEEEEECCCEEEEECCCEEECCEEEEEEECCCCCEEEECHHHHCCEEEEECCCCHHHHH
VIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASGRLDNLSSVHPSMTALIAASQS
HHHCCHHCCHHHHHCCCEEEEEECCCCEECCCCCEEECCCCCCCHHCCCCEEEEEEECCC
DDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMVS
CCCCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEE
ADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQV
CCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHCCCEEEEEEECCCCHHE
FAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSAREMAGVKDLMWFEQALEAYLVN
ECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHVTDDFLSFIALSPSSYHAAAAVERRLLHEGFIRQEDTDEWDARPGGHVTVRGGAVVAW
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEE
WVPEDASPDSGFRIIGSHTDSPGFKLKPRGDLSSHGWQQAGVEVYGGPILPSWLDRELAL
ECCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHHCCEEEECCCCCHHHHCCHHHH
AGRIVLADGSVKLVNTGPILRIPHVAIHLDRTVNSQLTLNPQRHLQPVFAVGEPDVSILD
CCEEEEECCCEEEEECCCEEECCEEEEEEECCCCCEEEECHHHHCCEEEEECCCCHHHHH
VIAGAAVVDPADIVSHDLITVATQDAEVFGAHGDFLASGRLDNLSSVHPSMTALIAASQS
HHHCCHHCCHHHHHCCCEEEEEECCCCEECCCCCEEECCCCCCCHHCCCCEEEEEEECCC
DDTGSDILVLAAFDHEEVGSNSTSGAGGPLLEDVLNRTARALGADEDERRRMFNRSTMVS
CCCCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEE
ADAAHSIHPNFPEKHDQANYPIIGKGPVLKVNANQRYTSDAVTSGMWIRACQIAGVPHQV
CCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHCCCEEEEEEECCCCHHE
FAGNNDVPCGSTIGPISATRLGIDSVDVGIPLLSMHSAREMAGVKDLMWFEQALEAYLVN
ECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]