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The map label for this gene is pimT [H]

Identifier: 62390380

GI number: 62390380

Start: 1580031

End: 1580867

Strand: Reverse

Name: pimT [H]

Synonym: cg1692

Alternate gene names: 62390380

Gene position: 1580867-1580031 (Counterclockwise)

Preceding gene: 62390381

Following gene: 62390379

Centisome position: 48.16

GC content: 56.51

Gene sequence:

>837_bases
ATGCCCTACTCAGGTCCGTTCCAAGCAGGCGACCGCGTTCAGCTCACCGACGCTAAACGCCGCCATTTCACCATCATTTT
GGAACCAGGAACCACCTACCACACCCACCGTGGACAAATCGCACACGATGACATCATCGGCGCCGATGAGGGCACTGTTG
TCCACTCCACCATGGGCTCTGATTACTTGTGCTTCCGTCACCTCATGGTTGATCACGTGCTGAGCATGCCTCGTGGCGCT
GCAGTTATTTATCCAAAGGACTCTGCACAGATTCTGGTCGAGGGCGATATTTTCCCTGGCGCCCGAGTTCTGGAAGCTGG
CGCTGGTTCCGGTGCACTGTCCATGGCGCTGCTTCGTGCAGTGGGTGAAAAGGGCAATGTCATCTCCTACGAAATCCGTG
AGGATCACCTGGAGTACGCAGTCTCCAACGTGGAGGAGTACTTCGGTGAGCGTCCAGCAACCTGGGATCCACGTCTTGGT
GACCTGAAAGAAGTCACCGTTGAGGATCTCGGCGGACCTGTTGACCGCATCATCTTGGATATGCTTGAGCCGTGGGAAAT
GCTGGAGACCTGCAAGGATCTTCTCATCCCTGGTGGTGTGTTTATGACGTATGTGGCGACCGTGCCACAGCTGATGAAGG
TCATGGAAGGCATCCGCGAGCAAAAATGCTTCACGGAGCCACGCGCGTGGGAATCTTTGGTTCGTGATTGGAAGGTGGAG
GGCTTGGCAACACGCCCTGAGCACCGCATGAATGCCCACACCGCGTTCTTGGTGTTGACCAGGCGTTTGGCTGATGGCGT
GGAGCCTCCTCGTCCGCAGCGTAAGGCACGTCGATAA

Upstream 100 bases:

>100_bases
AGTGAAGGATCTGATGTGGTTTGAACAAGCCCTGGAAGCCTATCTGGTAAATTAACGCCGAGTTCAATCAAGACAAGCAC
ACAGAAGAAAGTGAGGGCTC

Downstream 100 bases:

>100_bases
AAAGACCTAGTTGGAGGGCGTAAAGGGTTAGAGTGGTGACCATGAGTTCACCAACTGATTCTTCGCCCTCTAATTCTTTT
AGCGACTTCAACCGGGAGGA

Product: SAM-dependent methyltransferase involved in tRNA-Met maturation

Products: NA

Alternate protein names: tRNA(m1A58)-methyltransferase; tRNA(m1A58)MTase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MPYSGPFQAGDRVQLTDAKRRHFTIILEPGTTYHTHRGQIAHDDIIGADEGTVVHSTMGSDYLCFRHLMVDHVLSMPRGA
AVIYPKDSAQILVEGDIFPGARVLEAGAGSGALSMALLRAVGEKGNVISYEIREDHLEYAVSNVEEYFGERPATWDPRLG
DLKEVTVEDLGGPVDRIILDMLEPWEMLETCKDLLIPGGVFMTYVATVPQLMKVMEGIREQKCFTEPRAWESLVRDWKVE
GLATRPEHRMNAHTAFLVLTRRLADGVEPPRPQRKARR

Sequences:

>Translated_278_residues
MPYSGPFQAGDRVQLTDAKRRHFTIILEPGTTYHTHRGQIAHDDIIGADEGTVVHSTMGSDYLCFRHLMVDHVLSMPRGA
AVIYPKDSAQILVEGDIFPGARVLEAGAGSGALSMALLRAVGEKGNVISYEIREDHLEYAVSNVEEYFGERPATWDPRLG
DLKEVTVEDLGGPVDRIILDMLEPWEMLETCKDLLIPGGVFMTYVATVPQLMKVMEGIREQKCFTEPRAWESLVRDWKVE
GLATRPEHRMNAHTAFLVLTRRLADGVEPPRPQRKARR
>Mature_277_residues
PYSGPFQAGDRVQLTDAKRRHFTIILEPGTTYHTHRGQIAHDDIIGADEGTVVHSTMGSDYLCFRHLMVDHVLSMPRGAA
VIYPKDSAQILVEGDIFPGARVLEAGAGSGALSMALLRAVGEKGNVISYEIREDHLEYAVSNVEEYFGERPATWDPRLGD
LKEVTVEDLGGPVDRIILDMLEPWEMLETCKDLLIPGGVFMTYVATVPQLMKVMEGIREQKCFTEPRAWESLVRDWKVEG
LATRPEHRMNAHTAFLVLTRRLADGVEPPRPQRKARR

Specific function: Catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. Is required for cell growth at extreme temperatures [H]

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmI family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=246, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322336, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 31162; Mature: 31031

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSGPFQAGDRVQLTDAKRRHFTIILEPGTTYHTHRGQIAHDDIIGADEGTVVHSTMGS
CCCCCCCCCCCEEEEECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEECCCC
DYLCFRHLMVDHVLSMPRGAAVIYPKDSAQILVEGDIFPGARVLEAGAGSGALSMALLRA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
VGEKGNVISYEIREDHLEYAVSNVEEYFGERPATWDPRLGDLKEVTVEDLGGPVDRIILD
HCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
MLEPWEMLETCKDLLIPGGVFMTYVATVPQLMKVMEGIREQKCFTEPRAWESLVRDWKVE
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GLATRPEHRMNAHTAFLVLTRRLADGVEPPRPQRKARR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure 
PYSGPFQAGDRVQLTDAKRRHFTIILEPGTTYHTHRGQIAHDDIIGADEGTVVHSTMGS
CCCCCCCCCCEEEEECCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEECCCC
DYLCFRHLMVDHVLSMPRGAAVIYPKDSAQILVEGDIFPGARVLEAGAGSGALSMALLRA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
VGEKGNVISYEIREDHLEYAVSNVEEYFGERPATWDPRLGDLKEVTVEDLGGPVDRIILD
HCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
MLEPWEMLETCKDLLIPGGVFMTYVATVPQLMKVMEGIREQKCFTEPRAWESLVRDWKVE
HHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GLATRPEHRMNAHTAFLVLTRRLADGVEPPRPQRKARR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA