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The map label for this gene is cobL [H]

Identifier: 62390367

GI number: 62390367

Start: 1563989

End: 1565317

Strand: Reverse

Name: cobL [H]

Synonym: cg1678

Alternate gene names: 62390367

Gene position: 1565317-1563989 (Counterclockwise)

Preceding gene: 62390368

Following gene: 62390365

Centisome position: 47.68

GC content: 53.27

Gene sequence:

>1329_bases
ATGTATATCGTGGGGATTTGTCTACAATTAGTGGTTATGAGCCAACCGATGTCAGCACCCGACTCCGCTCCAGGAACAGA
GCGCGGTCATGAACGCACCCATTTTGCGGTAGTCGGTGACTCCCAGGATCCAGCACAGGCAACAGCTCCTAGAGCGCCAG
CAGAATCAATTACTTTGATTGGTATTGGTACCGATGGGTTTGAGGGGCTCGGACTCAAGGCACAGCAAGCATTACAACGT
GCCTCTGTGGTGATTGGATCATGGCGCCAGCTCAATCTCGTACCTGATGCCATTAAGGCAGAGCGTCGCCCATGGCCGGG
TAATACCAAGCATCCTGATTTAGATGCCTTGTTTAAAGAGTTCCTCGGTCGGCATGTTGCTGTTCTGGCCTCTGGCGATC
CACTGTTTTACGGCGTGGGCACCGCAATGGTCCATGTGCTGGGGATGGATAGACTCACGGTTATTCCGGGACCATCATCC
GCGTCGCTTGCTTGCGCCCGCTTGGGTTGGACAGTCAACCGCACACGGGTGGTGTACCTAGGACAAGAACCCATTGAGAC
ACTCATCCCGATTATTGAATCAGGCGCTCAATTCCTCGTCTTGGGTAAAGATGAATTCAGTACAGCTCAAGTTGCCACGT
TGTTGAATGAACTCGGACTGGGGGAGACTCCACTGACTGTGCTCAGCGATTTGGGCAGTACTGATGAGGAGATCACCCAA
GGCACAGCTTCACATCCACCAGCTGCAGTGTCTGTTCTCAACGTGATTGCTGTGGGAGCTCGCACCGCAATGCCGAAACC
CCACTTTGAAGGCGACGTATCAAACGAAGACCTTCGGGCACTGACCGTGGCAGCTCTAGAACCCACCCAGGGACAAATGC
TGTGGACCTTCGGGGATATTGGAGCAGCACTTGCCTGCGATTGGCTACGCGCAGCCGGCAACAAGGCGCACGCCATTAGT
TTTGCCTCCATGGTTGAGCAAAGCCAAAGGAATGCTCGCAAACTAGGTGTATCCACCCTCAGTGTGAAAGAGACCCTGTC
ACCCAAAACGCTCAAAGATATCCGCTATGTACAAGGACCAGAATCAGCAAGCCCACATGCCATCTTCATGAACAAAGGCC
TAGGCATCGATCTAGTTCCTGAAACCGCATGGATGATGCTGCGGCCTGGAGGAAAGCTCATTGCGCAAGCCTCCACAGAA
GACAACATCGCAAAGCTTCACACACTCCAAGAACAACACGGCGGAATCATCAAACACATCCGCATCGACGACACAGACGT
GCACCAATGGCGAGTTACAAAGCCGGTGACTCCAGAAGCGGTGAATTAG

Upstream 100 bases:

>100_bases
CATCGAATACGTGCCCTGCTGAATAGATGACATCGCAGAGATCTATAAGAGTCAGTGGTTGTCGGGGTTTCACAGTCACT
TATTCTATGCAGGATTCACC

Downstream 100 bases:

>100_bases
CATCAAAAACCAACCCCATGGGAGCCAGAACCTTCACCACCTGTTCTGCAACACCCTCATACAAATCATGAATGATCAAC
GAATTCCATGGGGTAATAGT

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MYIVGICLQLVVMSQPMSAPDSAPGTERGHERTHFAVVGDSQDPAQATAPRAPAESITLIGIGTDGFEGLGLKAQQALQR
ASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSS
ASLACARLGWTVNRTRVVYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQ
GTASHPPAAVSVLNVIAVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAIS
FASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTE
DNIAKLHTLQEQHGGIIKHIRIDDTDVHQWRVTKPVTPEAVN

Sequences:

>Translated_442_residues
MYIVGICLQLVVMSQPMSAPDSAPGTERGHERTHFAVVGDSQDPAQATAPRAPAESITLIGIGTDGFEGLGLKAQQALQR
ASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSS
ASLACARLGWTVNRTRVVYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQ
GTASHPPAAVSVLNVIAVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAIS
FASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTE
DNIAKLHTLQEQHGGIIKHIRIDDTDVHQWRVTKPVTPEAVN
>Mature_442_residues
MYIVGICLQLVVMSQPMSAPDSAPGTERGHERTHFAVVGDSQDPAQATAPRAPAESITLIGIGTDGFEGLGLKAQQALQR
ASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSS
ASLACARLGWTVNRTRVVYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQ
GTASHPPAAVSVLNVIAVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAIS
FASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTE
DNIAKLHTLQEQHGGIIKHIRIDDTDVHQWRVTKPVTPEAVN

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 47269; Mature: 47269

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIVGICLQLVVMSQPMSAPDSAPGTERGHERTHFAVVGDSQDPAQATAPRAPAESITLI
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCEEEE
GIGTDGFEGLGLKAQQALQRASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKE
EECCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHH
FLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTRVVYL
HHCCEEEEEECCCCEEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCEECCEEEEEE
GQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQ
CCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHC
GTASHPPAAVSVLNVIAVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCH
GAALACDWLRAAGNKAHAISFASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHCCC
ESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGIIKHI
CCCCCCEEEEECCCCEEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEE
RIDDTDVHQWRVTKPVTPEAVN
EECCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MYIVGICLQLVVMSQPMSAPDSAPGTERGHERTHFAVVGDSQDPAQATAPRAPAESITLI
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCEEEE
GIGTDGFEGLGLKAQQALQRASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKE
EECCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHH
FLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTRVVYL
HHCCEEEEEECCCCEEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCEECCEEEEEE
GQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQ
CCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHC
GTASHPPAAVSVLNVIAVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCH
GAALACDWLRAAGNKAHAISFASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHCCC
ESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGIIKHI
CCCCCCEEEEECCCCEEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEE
RIDDTDVHQWRVTKPVTPEAVN
EECCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]