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The map label for this gene is nudG [H]

Identifier: 62390041

GI number: 62390041

Start: 1208296

End: 1208691

Strand: Reverse

Name: nudG [H]

Synonym: cg1303

Alternate gene names: 62390041

Gene position: 1208691-1208296 (Counterclockwise)

Preceding gene: 62390043

Following gene: 62390040

Centisome position: 36.82

GC content: 52.02

Gene sequence:

>396_bases
GTGAAGAAACGCATCAATGTAACCGGCGCCGTCCTAGTCAAGGAAAACCGTATCCTTGCAGCACAACGTGGTCCAGAGAT
GTCACTTCCCGGATATTGGGAGTTTCCGGGAGGAAAGATCGAGCAGGGCGAAACTCCAGAAGCTTCACTTGCACGAGAGC
TCAAAGAAGAATTGCTTTGCGACGCCACCGTAGGCGAACACCTCACCACTACAGAGCACGAGTACGACTTTGGAATCGTC
GTGCTTTCCACCTACTTCTGCACACTAAATGATGCAGAGCCTCAATTGACCGAGCATGCTGAGATCCGCTGGGTGGCACC
ACACGAATTGGAATCTTTGGAGTGGGCACCTGCTGATATTCCTGCGGTGAAACTTCTCGTCGAGCAGCTTGCTTAA

Upstream 100 bases:

>100_bases
AAGGCAACAGAAAATCAATCTACCCCTGCGGGGTGCAACACAAAGGGGCACTTCATTACTGTTAGCATTGGGTTTCTGAC
CAGTAGTTCTGAGGAGAATC

Downstream 100 bases:

>100_bases
TGAGCCCATTCGATTCAAAGCTTGGTCGCGATACCCATTTTGGATTCCTCGATAAGACCACTGCTTCGCAACAACTGCTG
AATCCTTCATTGATTTCTAA

Product: NTP pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKRINVTGAVLVKENRILAAQRGPEMSLPGYWEFPGGKIEQGETPEASLARELKEELLCDATVGEHLTTTEHEYDFGIV
VLSTYFCTLNDAEPQLTEHAEIRWVAPHELESLEWAPADIPAVKLLVEQLA

Sequences:

>Translated_131_residues
MKKRINVTGAVLVKENRILAAQRGPEMSLPGYWEFPGGKIEQGETPEASLARELKEELLCDATVGEHLTTTEHEYDFGIV
VLSTYFCTLNDAEPQLTEHAEIRWVAPHELESLEWAPADIPAVKLLVEQLA
>Mature_131_residues
MKKRINVTGAVLVKENRILAAQRGPEMSLPGYWEFPGGKIEQGETPEASLARELKEELLCDATVGEHLTTTEHEYDFGIV
VLSTYFCTLNDAEPQLTEHAEIRWVAPHELESLEWAPADIPAVKLLVEQLA

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=119, Percent_Identity=37.8151260504202, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14641; Mature: 14641

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRINVTGAVLVKENRILAAQRGPEMSLPGYWEFPGGKIEQGETPEASLARELKEELLC
CCCCCCCCEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHC
DATVGEHLTTTEHEYDFGIVVLSTYFCTLNDAEPQLTEHAEIRWVAPHELESLEWAPADI
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
PAVKLLVEQLA
HHHHHHHHHHC
>Mature Secondary Structure
MKKRINVTGAVLVKENRILAAQRGPEMSLPGYWEFPGGKIEQGETPEASLARELKEELLC
CCCCCCCCEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHC
DATVGEHLTTTEHEYDFGIVVLSTYFCTLNDAEPQLTEHAEIRWVAPHELESLEWAPADI
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
PAVKLLVEQLA
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]