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The map label for this gene is sigC [H]

Identifier: 62389152

GI number: 62389152

Start: 273539

End: 274120

Strand: Reverse

Name: sigC [H]

Synonym: cg0309

Alternate gene names: 62389152

Gene position: 274120-273539 (Counterclockwise)

Preceding gene: 62389154

Following gene: 62389147

Centisome position: 8.35

GC content: 62.71

Gene sequence:

>582_bases
GTGAAGTCAAAAGAGCGTAACGACGCCCACGTCACCGAGCTGGCCCTAGCCGCCGGCCGTGGCGACCGCGCAGCTCTCAC
CGATTTCATCCGGGAAACCCAAGACGATGTCTGGCGTCTCCTCGCCCACCTTGGCGGCCACGAAATCGCCGACGATCTAA
CCCAAGAAACTTATCTGCGGGTCATGAGCGCCCTCCCCCGCTTCGCAGCGCGCTCCTCGGCGCGTACCTGGCTACTATCG
CTAGCCCGGCGCGTCTGGGTCGACAACATCCGACACGACATGGCACGCCCCCGCAAATCCATCGTCGAATACGAAGACAC
CGGTGCCACCGACGCGAGCAACGCAGGCATCTGGTCCGAGTGGATCGACGTGCGCACGCTTATCGACGCCCTCCCACCCG
AACGCCGCGAAGCCCTCATCCTCACCCAAGTGTTGGGCTACACCTACGAAGAAGCCGCAAAAATCGCCGACGTCCGAGTC
GGAACAATCCGTTCCCGCGTAGCCCGCGCCAGAGCGGACCTCATTGCTGCAACAGCTACCGGTGATTCCTCAGCCGAAGA
TGGCAAATCCGCCCAAGGTTAG

Upstream 100 bases:

>100_bases
CTGCCAGCAAAAAGACAAAAGTATGATACTTTTTGCCCACTTTGACACCCCCTACACACCTTTATGGTGACCCCGGTCTG
AACTGGTATTCTGAGCAATT

Downstream 100 bases:

>100_bases
CAGATGAGCTACGTCAACGGCGTAATCCCTTAACCAGATTGCTAATTTACAGTTCTATTTTGCTGCTCGATCAAAGCGAC
TCTTACCCACCCTAGAATCC

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKSKERNDAHVTELALAAGRGDRAALTDFIRETQDDVWRLLAHLGGHEIADDLTQETYLRVMSALPRFAARSSARTWLLS
LARRVWVDNIRHDMARPRKSIVEYEDTGATDASNAGIWSEWIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRV
GTIRSRVARARADLIAATATGDSSAEDGKSAQG

Sequences:

>Translated_193_residues
MKSKERNDAHVTELALAAGRGDRAALTDFIRETQDDVWRLLAHLGGHEIADDLTQETYLRVMSALPRFAARSSARTWLLS
LARRVWVDNIRHDMARPRKSIVEYEDTGATDASNAGIWSEWIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRV
GTIRSRVARARADLIAATATGDSSAEDGKSAQG
>Mature_193_residues
MKSKERNDAHVTELALAAGRGDRAALTDFIRETQDDVWRLLAHLGGHEIADDLTQETYLRVMSALPRFAARSSARTWLLS
LARRVWVDNIRHDMARPRKSIVEYEDTGATDASNAGIWSEWIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRV
GTIRSRVARARADLIAATATGDSSAEDGKSAQG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=164, Percent_Identity=31.0975609756098, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21386; Mature: 21386

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKERNDAHVTELALAAGRGDRAALTDFIRETQDDVWRLLAHLGGHEIADDLTQETYLR
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VMSALPRFAARSSARTWLLSLARRVWVDNIRHDMARPRKSIVEYEDTGATDASNAGIWSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
WIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRVGTIRSRVARARADLIAATAT
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDSSAEDGKSAQG
CCCCCCCCCCCCC
>Mature Secondary Structure
MKSKERNDAHVTELALAAGRGDRAALTDFIRETQDDVWRLLAHLGGHEIADDLTQETYLR
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VMSALPRFAARSSARTWLLSLARRVWVDNIRHDMARPRKSIVEYEDTGATDASNAGIWSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
WIDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRVGTIRSRVARARADLIAATAT
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDSSAEDGKSAQG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]