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The map label for this gene is moaC [H]

Identifier: 62389109

GI number: 62389109

Start: 227216

End: 227686

Strand: Reverse

Name: moaC [H]

Synonym: cg0260

Alternate gene names: 62389109

Gene position: 227686-227216 (Counterclockwise)

Preceding gene: 62389110

Following gene: 62389108

Centisome position: 6.94

GC content: 53.29

Gene sequence:

>471_bases
ATGAGCGAGCTCACCCACGTTCGAGCAGACGGTTCCGCACATATGGTGGATGTGACGGGCAAAAATGAAACATCGAGAAC
TGCTGTTGCCGAAGGGTTTGTGAAGATGAGGGGGGACGTCGTAAAGCAGCTTTTTAGTGCTGGTCTGCCTAAAGGCGACG
CGCTACCTGTGGCGCGGATTGCGGGTATCATGGGTGCGAAGAAGACGCCGGACATTATCCCTTTATGCCACCCGTTGCCG
CTGGGCAAAATTACTGTGGATTTTTTTGAGCTTACTGATGGTGTTCGGATTGAGGCTTCGGTGAAAACGCGTGGGGTTAC
TGGTGTGGAAATGGAGGCGTTGACGGCCGTGAGCACTGCGGCGCTGACGGTATACGACATGATCAAGGCTGTGGATAAGA
TGGCCGTGATTGATGGCATTCGTGTGCTGTCGAAAACTGGCGGTAAATCTGGGGATTGGTCTGTTCAGTGA

Upstream 100 bases:

>100_bases
CTGCCACCGCAGACTGTCTGATCAGGATCCCGGCGCGGACTACGGTGGAGGAAAACGACATCGTTAAGATTTACCCATTC
AACTAACAGGAGTTAATTTA

Downstream 100 bases:

>100_bases
CAGCTCTGGTTATCGTTGCGTCCACTCGCGCCGCTGCCGGGGTGTATGAGGATCGCTCTGGCCCAATTTTGGTGTCGTGG
CTGCGTGCAAAAGGTTTTGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSELTHVRADGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLP
LGKITVDFFELTDGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ

Sequences:

>Translated_156_residues
MSELTHVRADGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLP
LGKITVDFFELTDGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
>Mature_155_residues
SELTHVRADGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLPL
GKITVDFFELTDGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=54.4303797468354, Blast_Score=161, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=41.6107382550336, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=51.3333333333333, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28574492, Length=138, Percent_Identity=52.8985507246377, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16438; Mature: 16307

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELTHVRADGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARI
CCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AGIMGAKKTPDIIPLCHPLPLGKITVDFFELTDGVRIEASVKTRGVTGVEMEALTAVSTA
HHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHH
ALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SELTHVRADGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARI
CCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AGIMGAKKTPDIIPLCHPLPLGKITVDFFELTDGVRIEASVKTRGVTGVEMEALTAVSTA
HHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHH
ALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA