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The map label for this gene is panC [H]

Identifier: 62389008

GI number: 62389008

Start: 126351

End: 127190

Strand: Reverse

Name: panC [H]

Synonym: cg0148

Alternate gene names: 62389008

Gene position: 127190-126351 (Counterclockwise)

Preceding gene: 62389009

Following gene: 62389005

Centisome position: 3.87

GC content: 56.9

Gene sequence:

>840_bases
ATGCAGGTAGCAACCACAAAGCAGGCGCTTATCGACGCCCTCCTCCACCACAAATCCGTCGGGCTCGTCCCCACCATGGG
TGCGCTACACAGCGGACACGCCTCGTTGGTTAAAGCAGCACGCGCTGAAAACGACACTGTTGTAGCCAGTATTTTTGTCA
ATCCCCTGCAGTTTGAAGCACTCGGTGATTGCGATGATTACCGCAACTATCCCCGCCAACTCGACGCCGATTTAGCACTG
CTTGAAGAGGCAGGTGTGGATATTGTGTTCGCACCCGATGTGGAGGAAATGTACCCCGGTGGCTTGCCACTAGTGTGGGC
GCGCACCGGTTCCATCGGAACAAAATTGGAGGGTGCCAGCAGGCCTGGCCATTTCGATGGTGTGGCTACCGTGGTGGCGA
AGCTGTTCAATTTGGTGCGCCCTGATCGTGCATATTTTGGACAAAAAGATGCTCAGCAGGTTGCGGTGATTCGGCGATTG
GTTGCCGATCTAGACATTCCCGTGGAGATTCGTCCCGTTCCGATTATTCGTGGCGCCGATGGCTTAGCCGAATCCAGCCG
CAATCAACGTCTTTCTGCGGATCAGCGAGCGCAAGCTCTGGTGCTGCCGCAGGTGTTGAGTGGGTTGCAGCGTCGAAAAG
CAGCTGGTGAAGCGCTAGATATCCAAGGTGCGCGCGACACCTTGGCCAGCGCCGACGGCGTGCGCTTGGATCACCTGGAA
ATTGTCGATCCAGCCACCCTCGAACCATTAGAAATCGACGGCCTGCTCACCCAACCAGCGTTGGTGGTCGGCGCGATTTT
CGTGGGGCCGGTGCGGTTGATCGACAATATCGAGCTCTAG

Upstream 100 bases:

>100_bases
GCGAGTACGCCACCTTGGGCGATTCCTTGCACGACGCCGCGCAGGCCTACATCGCCGATATCCACGCGGGTACCTTCCCA
GGCGAAGCGGAGTCCTTTTA

Downstream 100 bases:

>100_bases
TACCAACCCTGCGTTGCAGCACGCAGCTTCGCATAACGCGTGCTCAGCTCAGTGTTTTTAGGTGCGCGGTGCGGATCGGA
ACCGGGAGTTGGCCACTGCG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MQVATTKQALIDALLHHKSVGLVPTMGALHSGHASLVKAARAENDTVVASIFVNPLQFEALGDCDDYRNYPRQLDADLAL
LEEAGVDIVFAPDVEEMYPGGLPLVWARTGSIGTKLEGASRPGHFDGVATVVAKLFNLVRPDRAYFGQKDAQQVAVIRRL
VADLDIPVEIRPVPIIRGADGLAESSRNQRLSADQRAQALVLPQVLSGLQRRKAAGEALDIQGARDTLASADGVRLDHLE
IVDPATLEPLEIDGLLTQPALVVGAIFVGPVRLIDNIEL

Sequences:

>Translated_279_residues
MQVATTKQALIDALLHHKSVGLVPTMGALHSGHASLVKAARAENDTVVASIFVNPLQFEALGDCDDYRNYPRQLDADLAL
LEEAGVDIVFAPDVEEMYPGGLPLVWARTGSIGTKLEGASRPGHFDGVATVVAKLFNLVRPDRAYFGQKDAQQVAVIRRL
VADLDIPVEIRPVPIIRGADGLAESSRNQRLSADQRAQALVLPQVLSGLQRRKAAGEALDIQGARDTLASADGVRLDHLE
IVDPATLEPLEIDGLLTQPALVVGAIFVGPVRLIDNIEL
>Mature_279_residues
MQVATTKQALIDALLHHKSVGLVPTMGALHSGHASLVKAARAENDTVVASIFVNPLQFEALGDCDDYRNYPRQLDADLAL
LEEAGVDIVFAPDVEEMYPGGLPLVWARTGSIGTKLEGASRPGHFDGVATVVAKLFNLVRPDRAYFGQKDAQQVAVIRRL
VADLDIPVEIRPVPIIRGADGLAESSRNQRLSADQRAQALVLPQVLSGLQRRKAAGEALDIQGARDTLASADGVRLDHLE
IVDPATLEPLEIDGLLTQPALVVGAIFVGPVRLIDNIEL

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=268, Percent_Identity=47.0149253731343, Blast_Score=209, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322046, Length=286, Percent_Identity=40.2097902097902, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 29889; Mature: 29889

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVATTKQALIDALLHHKSVGLVPTMGALHSGHASLVKAARAENDTVVASIFVNPLQFEA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEEECCHHEEE
LGDCDDYRNYPRQLDADLALLEEAGVDIVFAPDVEEMYPGGLPLVWARTGSIGTKLEGAS
CCCCHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHCCCCCEEEEEECCCCCCCCCCCC
RPGHFDGVATVVAKLFNLVRPDRAYFGQKDAQQVAVIRRLVADLDIPVEIRPVPIIRGAD
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEECCC
GLAESSRNQRLSADQRAQALVLPQVLSGLQRRKAAGEALDIQGARDTLASADGVRLDHLE
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHCCCCCEECEEE
IVDPATLEPLEIDGLLTQPALVVGAIFVGPVRLIDNIEL
ECCCCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVATTKQALIDALLHHKSVGLVPTMGALHSGHASLVKAARAENDTVVASIFVNPLQFEA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEEECCHHEEE
LGDCDDYRNYPRQLDADLALLEEAGVDIVFAPDVEEMYPGGLPLVWARTGSIGTKLEGAS
CCCCHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHCCCCCEEEEEECCCCCCCCCCCC
RPGHFDGVATVVAKLFNLVRPDRAYFGQKDAQQVAVIRRLVADLDIPVEIRPVPIIRGAD
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEECCC
GLAESSRNQRLSADQRAQALVLPQVLSGLQRRKAAGEALDIQGARDTLASADGVRLDHLE
CHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHCCCCCEECEEE
IVDPATLEPLEIDGLLTQPALVVGAIFVGPVRLIDNIEL
ECCCCCCCCEEECCCHHCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA