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The map label for this gene is agaR [H]

Identifier: 62389001

GI number: 62389001

Start: 118808

End: 119590

Strand: Reverse

Name: agaR [H]

Synonym: cg0139

Alternate gene names: 62389001

Gene position: 119590-118808 (Counterclockwise)

Preceding gene: 62389003

Following gene: 62389000

Centisome position: 3.64

GC content: 59.13

Gene sequence:

>783_bases
ATGGAGCGCGAACAACGACACAAAGTGATCATGCGAACGATCGACCGCCCCGGAATCACACGCATTGATGCTCTTACTGA
ACTAACTGGGGTTTCCGCGGTGACCATTCACCGGGATCTCGTCGAGCTAGAGCAAGCAGGTTTCCTCGCCCGCACCCACG
GTGGAGCGAAACGTGTGCCCAAACGCGGTACTCCCCAACCGTTTGCCGTGCGCCAGGCTGAGGACCGAGAGGCCAAACGC
ATTTTGGCCCAGGCCACCGCCCAACTAATCGCTGATGATGAAGCAGTAATTTTCGACAACGGCACCACCTGCCAGGCAGT
GGCCCAAGAGTTGGCGGGGCGTCCCATCACGGCATTGTGTCTGTCTCTACATTCGGCGGTCGCCCTGGGAAGCCGAGCTG
GCACCAACGTTTTCATCCCCGGCGGCCCCGTGGAAAACGACTCACTCGCCTTATCTGGCCCGGCTGTGATCACCGCGTTA
CGAGATTTCTCCGCCGATGTCGTGATCCTCGGTTCCTGCTCTACATCACTGGAGCACGGGTTGGCCACCACTACCTACGA
CGATGCGGAAAACAAGCGCGCAGCCATCCATGCTGCCACCCGACGAATCCTTGTGGTGTCCGCCCGTAAACTCAACCACG
TTTCCACTTTCCGTTTCGCAGACGTCGCGGACTTACACCAGCTGGTCACAACCTCCGATGCGCCACGGGAGATTCTCGCC
GAGATCCGGGATCTCGGCGTGCAGGTTATTACTGTTCCCGCCCCTGACGAGCAACGAAGTTAA

Upstream 100 bases:

>100_bases
GTCCCGTGACCCCAGAATTTGCACGAAAAGGCATTTTAACCAGTGTTCATTCGGTTAGGTCAGGGTTGACATTCTTTAGG
AATTAGCGAATTCTGATCAC

Downstream 100 bases:

>100_bases
CTCTTCATGGTTGCTGAGCAGTTCTAAACATCCCCAAAAGGCCTGCCCAAGTGAAAGGATTGTTAAAAAAATTTCTCCAA
CTCGGGGCAGACCCTAACAG

Product: DeoR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEREQRHKVIMRTIDRPGITRIDALTELTGVSAVTIHRDLVELEQAGFLARTHGGAKRVPKRGTPQPFAVRQAEDREAKR
ILAQATAQLIADDEAVIFDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTNVFIPGGPVENDSLALSGPAVITAL
RDFSADVVILGSCSTSLEHGLATTTYDDAENKRAAIHAATRRILVVSARKLNHVSTFRFADVADLHQLVTTSDAPREILA
EIRDLGVQVITVPAPDEQRS

Sequences:

>Translated_260_residues
MEREQRHKVIMRTIDRPGITRIDALTELTGVSAVTIHRDLVELEQAGFLARTHGGAKRVPKRGTPQPFAVRQAEDREAKR
ILAQATAQLIADDEAVIFDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTNVFIPGGPVENDSLALSGPAVITAL
RDFSADVVILGSCSTSLEHGLATTTYDDAENKRAAIHAATRRILVVSARKLNHVSTFRFADVADLHQLVTTSDAPREILA
EIRDLGVQVITVPAPDEQRS
>Mature_260_residues
MEREQRHKVIMRTIDRPGITRIDALTELTGVSAVTIHRDLVELEQAGFLARTHGGAKRVPKRGTPQPFAVRQAEDREAKR
ILAQATAQLIADDEAVIFDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTNVFIPGGPVENDSLALSGPAVITAL
RDFSADVVILGSCSTSLEHGLATTTYDDAENKRAAIHAATRRILVVSARKLNHVSTFRFADVADLHQLVTTSDAPREILA
EIRDLGVQVITVPAPDEQRS

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=257, Percent_Identity=29.9610894941634, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=26, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=24.0157480314961, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789059, Length=260, Percent_Identity=24.6153846153846, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=24.3478260869565, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789170, Length=210, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787063, Length=221, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27919; Mature: 27919

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREQRHKVIMRTIDRPGITRIDALTELTGVSAVTIHRDLVELEQAGFLARTHGGAKRVP
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHCCCEEECCCCHHCCC
KRGTPQPFAVRQAEDREAKRILAQATAQLIADDEAVIFDNGTTCQAVAQELAGRPITALC
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCHHHHH
LSLHSAVALGSRAGTNVFIPGGPVENDSLALSGPAVITALRDFSADVVILGSCSTSLEHG
HHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHCCCCEEEEECCCHHHHCC
LATTTYDDAENKRAAIHAATRRILVVSARKLNHVSTFRFADVADLHQLVTTSDAPREILA
CCCCCCCCCCCHHHHHHHHHHEEEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
EIRDLGVQVITVPAPDEQRS
HHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MEREQRHKVIMRTIDRPGITRIDALTELTGVSAVTIHRDLVELEQAGFLARTHGGAKRVP
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHCCCEEECCCCHHCCC
KRGTPQPFAVRQAEDREAKRILAQATAQLIADDEAVIFDNGTTCQAVAQELAGRPITALC
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCHHHHH
LSLHSAVALGSRAGTNVFIPGGPVENDSLALSGPAVITALRDFSADVVILGSCSTSLEHG
HHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCHHHHHHHHHCCCCEEEEECCCHHHHCC
LATTTYDDAENKRAAIHAATRRILVVSARKLNHVSTFRFADVADLHQLVTTSDAPREILA
CCCCCCCCCCCHHHHHHHHHHEEEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
EIRDLGVQVITVPAPDEQRS
HHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]