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The map label for this gene is trpS [H]

Identifier: 62185530

GI number: 62185530

Start: 1084885

End: 1085922

Strand: Direct

Name: trpS [H]

Synonym: CAB930

Alternate gene names: 62185530

Gene position: 1084885-1085922 (Clockwise)

Preceding gene: 62185529

Following gene: 62185531

Centisome position: 94.8

GC content: 41.71

Gene sequence:

>1038_bases
ATGAACAAAAAAACGCGCGTACTTACCGGTGATCGACCAACAGGCAAGCTCCATTTAGGTCACTGGGTAGGCTCTATAAA
AAATCGTTTAGACTTACAGAATAACCCAGCGTACGATTGCTTTTTTATCGTTGCGGATCTCCACACTCTTACAACCAGAA
TACGTAAAGAACAAGTGCTCAATGTGGATAACCACATTTATGAAGTTCTTGCAGACTGGTTAAGTGTGGGGATAGATCCG
AATAAATCGACTATCTATTTACAGTCGGCCATACCGGAAATCTACGAACTCCACTTACTGTTTTCCATGTTGATTTCGAT
TAATCGCATCATGGGGATTCCGAGTCTTAAGGAAATGGCGAAGAACGCTTCTATAGATGAGGGTGGTTTGTCCTTTGGAT
TGGTGGGCTATCCAGTTTTACAAAGCGCGGATATTCTTCTTGCTAAAGCGCAACTCGTTCCCGTAGGTAAAGATAATGAA
GCCCATATAGAGCTAACTCGTGATATTGCTCGCAATTTTAATCGTTTATACGGTGAGATATTCCCCGAGCCAGAGACTCT
ACAAGGAGAACTTACCTCTTTAGTCGGCATTGACGGCCAAGGGAAAATGAGTAAATCTGCGAATAACGCCATCTACCTTT
CTGATGATGATGCAACTATCAAAGATAAGATCAGAAAAATGTATACCGACCCAAATCGAATTCACGCTACGACCCCAGGG
CGAGTCGAAGGGAACCCTCTATTCATCTATCATGATATTTTCAATCCTAATAAAGAAGAAGTTGAAGAATTTAAAACACG
TTACCGTCAAGGATGTATAAAAGATGTTGAGATCAAGGCACGCCTTGCCGAAGAACTTATTCTCTTTTTACAACCTTTGA
AAGAAAAACGTGCCGAACTACTTACAAAACCTCAAGCCCTTCAAGATGCATTACAACTGGGCACAGAAAAAATGCGTGCT
GTAGCCAAAGAAACCATGGAAGAAGTCCATGACACCTTAGGGTTAAGCCATAAATGGCGCTCTCGTTTACTACCTTAA

Upstream 100 bases:

>100_bases
CTGTAGGAGAAAAAAACCTCCTAGAAATTCAAGAAGATATCGTATCATTGAAGAATCACTTCGAAGAACTAGAAAAATCT
CTTCAATAAAATAAAATTCT

Downstream 100 bases:

>100_bases
TTGCTATATGCTCCTATGACCTTTGAATTACGCGCTGCTTTTTCGCCTTGTGGAGATCAGCCCGAAGCTATTGCTAAACT
CACGCAAGGCGTACGTAATC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNKKTRVLTGDRPTGKLHLGHWVGSIKNRLDLQNNPAYDCFFIVADLHTLTTRIRKEQVLNVDNHIYEVLADWLSVGIDP
NKSTIYLQSAIPEIYELHLLFSMLISINRIMGIPSLKEMAKNASIDEGGLSFGLVGYPVLQSADILLAKAQLVPVGKDNE
AHIELTRDIARNFNRLYGEIFPEPETLQGELTSLVGIDGQGKMSKSANNAIYLSDDDATIKDKIRKMYTDPNRIHATTPG
RVEGNPLFIYHDIFNPNKEEVEEFKTRYRQGCIKDVEIKARLAEELILFLQPLKEKRAELLTKPQALQDALQLGTEKMRA
VAKETMEEVHDTLGLSHKWRSRLLP

Sequences:

>Translated_345_residues
MNKKTRVLTGDRPTGKLHLGHWVGSIKNRLDLQNNPAYDCFFIVADLHTLTTRIRKEQVLNVDNHIYEVLADWLSVGIDP
NKSTIYLQSAIPEIYELHLLFSMLISINRIMGIPSLKEMAKNASIDEGGLSFGLVGYPVLQSADILLAKAQLVPVGKDNE
AHIELTRDIARNFNRLYGEIFPEPETLQGELTSLVGIDGQGKMSKSANNAIYLSDDDATIKDKIRKMYTDPNRIHATTPG
RVEGNPLFIYHDIFNPNKEEVEEFKTRYRQGCIKDVEIKARLAEELILFLQPLKEKRAELLTKPQALQDALQLGTEKMRA
VAKETMEEVHDTLGLSHKWRSRLLP
>Mature_345_residues
MNKKTRVLTGDRPTGKLHLGHWVGSIKNRLDLQNNPAYDCFFIVADLHTLTTRIRKEQVLNVDNHIYEVLADWLSVGIDP
NKSTIYLQSAIPEIYELHLLFSMLISINRIMGIPSLKEMAKNASIDEGGLSFGLVGYPVLQSADILLAKAQLVPVGKDNE
AHIELTRDIARNFNRLYGEIFPEPETLQGELTSLVGIDGQGKMSKSANNAIYLSDDDATIKDKIRKMYTDPNRIHATTPG
RVEGNPLFIYHDIFNPNKEEVEEFKTRYRQGCIKDVEIKARLAEELILFLQPLKEKRAELLTKPQALQDALQLGTEKMRA
VAKETMEEVHDTLGLSHKWRSRLLP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=344, Percent_Identity=32.2674418604651, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=39.0374331550802, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1789786, Length=343, Percent_Identity=31.1953352769679, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=29.3255131964809, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=29.3255131964809, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=357, Percent_Identity=31.6526610644258, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39082; Mature: 39082

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTRVLTGDRPTGKLHLGHWVGSIKNRLDLQNNPAYDCFFIVADLHTLTTRIRKEQVL
CCCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NVDNHIYEVLADWLSVGIDPNKSTIYLQSAIPEIYELHLLFSMLISINRIMGIPSLKEMA
CHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KNASIDEGGLSFGLVGYPVLQSADILLAKAQLVPVGKDNEAHIELTRDIARNFNRLYGEI
HCCCCCCCCCEECHHHHHHHCCCHHEEEHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FPEPETLQGELTSLVGIDGQGKMSKSANNAIYLSDDDATIKDKIRKMYTDPNRIHATTPG
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEECCCCC
RVEGNPLFIYHDIFNPNKEEVEEFKTRYRQGCIKDVEIKARLAEELILFLQPLKEKRAEL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTKPQALQDALQLGTEKMRAVAKETMEEVHDTLGLSHKWRSRLLP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MNKKTRVLTGDRPTGKLHLGHWVGSIKNRLDLQNNPAYDCFFIVADLHTLTTRIRKEQVL
CCCCCEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NVDNHIYEVLADWLSVGIDPNKSTIYLQSAIPEIYELHLLFSMLISINRIMGIPSLKEMA
CHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KNASIDEGGLSFGLVGYPVLQSADILLAKAQLVPVGKDNEAHIELTRDIARNFNRLYGEI
HCCCCCCCCCEECHHHHHHHCCCHHEEEHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FPEPETLQGELTSLVGIDGQGKMSKSANNAIYLSDDDATIKDKIRKMYTDPNRIHATTPG
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEECCCCC
RVEGNPLFIYHDIFNPNKEEVEEFKTRYRQGCIKDVEIKARLAEELILFLQPLKEKRAEL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTKPQALQDALQLGTEKMRAVAKETMEEVHDTLGLSHKWRSRLLP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]