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The map label for this gene is bioD

Identifier: 62185300

GI number: 62185300

Start: 797790

End: 798413

Strand: Direct

Name: bioD

Synonym: CAB687

Alternate gene names: 62185300

Gene position: 797790-798413 (Clockwise)

Preceding gene: 62185299

Following gene: 62185301

Centisome position: 69.71

GC content: 42.95

Gene sequence:

>624_bases
ATGCATATTATCATAGCAGGAATTGATACAGACGTCGGCAAGACATTCGTTAGCGCCATCTTAACGGTCCTACTTCAAGC
AGAATATTGGAAGCCTATACAATCTGGCTCCTTAAACCACTCTGATAGTGCCATAGTTCATGCACTCTCAGGAGCCCGCT
GCCACCCAGAATCTTACCGATTTTCTCATGCTCTAGCAGCCCACCAAGCAGCTCAAATCGATAATATTACTATGCATCAA
GAAACGATCACTCTGCCAAAAACAGATGCTTCTCTCATTATTGAAACTTCAGGAGGATTCCTCTCCCCCTGCACACATGA
TTCTTTACAGGGTGATGTTTTTGCGCAATGGCCGTGCCATTGGGTGCTGGTGAGCAAAGCCTATTTAGGAAGTATCAATC
ACACGTGTTTAACACTAGAGGCTATGCGAGCAAGAAACCTCAGCATCTTAGGAATCATTCTCAATCAATACCCTAAGGAA
GAAGAAGACTGGTTACTGCGTACGACCGGTCTGCCTTTTTTGGGACGTTTGAATTATGAAAAGAGTATTTCCAAAGCTAC
AGTACAAAACTACGCAAATTTATGGAAAGAAACCTGGAAATATAGAGACACACTGTTATGTTGA

Upstream 100 bases:

>100_bases
AACAAAAAGAAGAATTATTACGGATCTGTCTTCACTCGTTTAATACCCAAAGTGAAATCACAGAATTCTTGAATAAATTA
TACGCAGTTCAAAAAGGCTT

Downstream 100 bases:

>100_bases
CAGATCTAAAAAATGAGAAAAAACAATCTAAAATATGGCATCCCTTTGCTCAACCTGGTTTAGATCACAAACCTATCCAC
ATTGTACGTGGAGAAGGTGC

Product: putative dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MHIIIAGIDTDVGKTFVSAILTVLLQAEYWKPIQSGSLNHSDSAIVHALSGARCHPESYRFSHALAAHQAAQIDNITMHQ
ETITLPKTDASLIIETSGGFLSPCTHDSLQGDVFAQWPCHWVLVSKAYLGSINHTCLTLEAMRARNLSILGIILNQYPKE
EEDWLLRTTGLPFLGRLNYEKSISKATVQNYANLWKETWKYRDTLLC

Sequences:

>Translated_207_residues
MHIIIAGIDTDVGKTFVSAILTVLLQAEYWKPIQSGSLNHSDSAIVHALSGARCHPESYRFSHALAAHQAAQIDNITMHQ
ETITLPKTDASLIIETSGGFLSPCTHDSLQGDVFAQWPCHWVLVSKAYLGSINHTCLTLEAMRARNLSILGIILNQYPKE
EEDWLLRTTGLPFLGRLNYEKSISKATVQNYANLWKETWKYRDTLLC
>Mature_207_residues
MHIIIAGIDTDVGKTFVSAILTVLLQAEYWKPIQSGSLNHSDSAIVHALSGARCHPESYRFSHALAAHQAAQIDNITMHQ
ETITLPKTDASLIIETSGGFLSPCTHDSLQGDVFAQWPCHWVLVSKAYLGSINHTCLTLEAMRARNLSILGIILNQYPKE
EEDWLLRTTGLPFLGRLNYEKSISKATVQNYANLWKETWKYRDTLLC

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324385, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOD_CHLAB (Q5L5F7)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220085.1
- ProteinModelPortal:   Q5L5F7
- GeneID:   3337274
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB687
- HOGENOM:   HBG650065
- OMA:   WKPIQSG
- ProtClustDB:   CLSK399497
- BioCyc:   CABO218497:CAB687-MONOMER
- HAMAP:   MF_00336
- InterPro:   IPR004472
- PIRSF:   PIRSF006755
- TIGRFAMs:   TIGR00347

Pfam domain/function: NA

EC number: =6.3.3.3

Molecular weight: Translated: 23165; Mature: 23165

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIIIAGIDTDVGKTFVSAILTVLLQAEYWKPIQSGSLNHSDSAIVHALSGARCHPESYR
CEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHH
FSHALAAHQAAQIDNITMHQETITLPKTDASLIIETSGGFLSPCTHDSLQGDVFAQWPCH
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCEE
WVLVSKAYLGSINHTCLTLEAMRARNLSILGIILNQYPKEEEDWLLRTTGLPFLGRLNYE
EEEEHHHHHCCCCCCEEEHHHHHHCCCEEEEEEHHCCCCCCCCEEEEECCCCCEECCCHH
KSISKATVQNYANLWKETWKYRDTLLC
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHIIIAGIDTDVGKTFVSAILTVLLQAEYWKPIQSGSLNHSDSAIVHALSGARCHPESYR
CEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHH
FSHALAAHQAAQIDNITMHQETITLPKTDASLIIETSGGFLSPCTHDSLQGDVFAQWPCH
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCEE
WVLVSKAYLGSINHTCLTLEAMRARNLSILGIILNQYPKEEEDWLLRTTGLPFLGRLNYE
EEEEHHHHHCCCCCCEEEHHHHHHCCCEEEEEEHHCCCCCCCCEEEEECCCCCEECCCHH
KSISKATVQNYANLWKETWKYRDTLLC
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA