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The map label for this gene is hlyB [H]

Identifier: 59711384

GI number: 59711384

Start: 847506

End: 849380

Strand: Reverse

Name: hlyB [H]

Synonym: VF_0777

Alternate gene names: 59711384

Gene position: 849380-847506 (Counterclockwise)

Preceding gene: 59711386

Following gene: 59711383

Centisome position: 29.31

GC content: 40.16

Gene sequence:

>1875_bases
ATGAAATTAAAACATAAGTTAATCGGTGCTAGTTTACTTGCTGTCATCATCACTGCCTCTGCTCTTACTTGGTTGGCTTC
TAACCAACTGTTTGAACAAACACGCAATGGTGTCTATTCACGTGCAGAAAGCGTTACATCTGCTGCAACAACCGGTATAT
CAAACTGGATAACATTAAAAGCTGAAATTGCACATGCCTTTAATGACTATAGCCAAGAAGAAGATGTTGTTTCATTCCTA
CAAATCAGTCGTAAAGCTGGTGGATTTGATGACATTTTCTTTGGAACACCACAAGGCGAAATGTTCCGCTCCCACCCCGA
GAGAAATCGAGCAGATTACGACCCTCGTCAACGACCTTGGTATCAAGAAGCTCAACGTGAAAATAAGCAGATCATCACCT
CTTCTTATCAAGATGCTATCACTCAGTCTCTACTGGTAACCATCGCAGAACCTGTCTATCAAAATGGTCAATTTTTAGGT
GTTGTTGGTGCTGACGTTCTTATTGATCAATTAATTGATGATGTGATCAGTTTAGATGCAGGTAAAGATACCATTACGAT
GCTAATTGATAGTGACGGCACGTTCCTAGCTCACCCAAATAAAGCGCTAATTAAAAAAGAAGTGAATCGCTATTTCAGCG
ATATGAGCGCCCAAAGTATTCAAGATTCAATCAGCGCAAATCGCATTGAAGTTGCTAATATTAACGGCAGTGAAAAACTG
GTTTATTTCGCTAAAGTACCAAATACTAATTGGACATTTGCAGTTGAAATGACAAAAGAAACAGAAGAAGCGGCTCACAG
TGCCCTACTTCGTGAAATCATTTTATTAAGCATTGTGTTAACGGTAATTGTTGCTATTGGTGTAACAACATTAGTTAATC
TTTTATTTAGAGATTTAATCCGAGTATCAGACGCACTAGCAGAAATATCATCTGGTGAAGGCGATTTAACTCAACGTCTA
GAACCTCATAGCGATGACGAAGTCGGTCAACTTGCCATTAACTTTAATACCTTTGTTGGTAACATGCATTCAATGGTATG
TCGTTTACGTGATATTTCAGTAACACTAGCAAACCAAGCAAACTCTACGGCAGAGGGAGCGGAAGAACGTAATGTTCGTA
TCCAACATCAAATGGATGAAATCAATATGGTTGCAACTGCGATTAATGAAATGGCAGCAGCGACACAAGAGATTGCGGGT
AATGCTGATAATACAGCTCAAACAGCTGAAGAAACCGTGACAGCATCAAATCATGGTGCAGAGCAAGTGAGCCAAAGCCA
ACACTCTATCGACAACCTTGCAAAAGAAGTCGAAACAGCAACTGGCGTTATTGAAGAACTTCACCATAATGCTCAGAACA
TCAATACGATTCTTTCAACAATCCAAAACATTGCAGAACAAACTAACTTGCTTGCATTAAATGCTGCTATTGAAGCAGCT
CGAGCAGGCGAACAAGGTCGTGGTTTTGCAGTAGTTGCTGATGAAGTTCGAATTCTAAGCCAACGAACTCATGCTTCTAC
TCAAGAAATTCAGCAAATGATCGAAACACTGCAAGGAACAACTCAAAAAGCAGTTGGCATTATGGAAGATAGCCAGAACC
TTGCAAATACAAGTGTAGAAGATGCGCAATCGGCCTCAGCAAGCTTGTTGCAAATCACGAACTCAGTGACTCAAATAAGT
GATATGGCAGCTCAAATTGCTGCGGCCGCCGAAGAGCAATCATCTGTAACTGAAGAAATCACACGTAATACTGAAGCGGT
TCGTGATGTTTCAAACGAACTAACAGAAGAAACAAAACAATCTGTCATTCAGGCGTCTGAACTCTCTGAACTGTCAAATG
AATTAAAACAAGAAATCGACCGATTTAAACTGTAA

Upstream 100 bases:

>100_bases
TTCACTTTGCCCCGATAACATAATCAAAGCTTATAATAAGACCAACAAATCACAGCTTTTTAATATTAATGGATTACTTT
TAATAAGATTAGGCAAAATC

Downstream 100 bases:

>100_bases
ATTCATTAAACATATCCCTAAATTAAAGACAGAACGTGAATTCACATTCTGTCTTTTTTTTTCAGAAACTCAGAATAAAA
CCAACAAAAAAGAAAATAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MKLKHKLIGASLLAVIITASALTWLASNQLFEQTRNGVYSRAESVTSAATTGISNWITLKAEIAHAFNDYSQEEDVVSFL
QISRKAGGFDDIFFGTPQGEMFRSHPERNRADYDPRQRPWYQEAQRENKQIITSSYQDAITQSLLVTIAEPVYQNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLAHPNKALIKKEVNRYFSDMSAQSIQDSISANRIEVANINGSEKL
VYFAKVPNTNWTFAVEMTKETEEAAHSALLREIILLSIVLTVIVAIGVTTLVNLLFRDLIRVSDALAEISSGEGDLTQRL
EPHSDDEVGQLAINFNTFVGNMHSMVCRLRDISVTLANQANSTAEGAEERNVRIQHQMDEINMVATAINEMAAATQEIAG
NADNTAQTAEETVTASNHGAEQVSQSQHSIDNLAKEVETATGVIEELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTQIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTEETKQSVIQASELSELSNELKQEIDRFKL

Sequences:

>Translated_624_residues
MKLKHKLIGASLLAVIITASALTWLASNQLFEQTRNGVYSRAESVTSAATTGISNWITLKAEIAHAFNDYSQEEDVVSFL
QISRKAGGFDDIFFGTPQGEMFRSHPERNRADYDPRQRPWYQEAQRENKQIITSSYQDAITQSLLVTIAEPVYQNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLAHPNKALIKKEVNRYFSDMSAQSIQDSISANRIEVANINGSEKL
VYFAKVPNTNWTFAVEMTKETEEAAHSALLREIILLSIVLTVIVAIGVTTLVNLLFRDLIRVSDALAEISSGEGDLTQRL
EPHSDDEVGQLAINFNTFVGNMHSMVCRLRDISVTLANQANSTAEGAEERNVRIQHQMDEINMVATAINEMAAATQEIAG
NADNTAQTAEETVTASNHGAEQVSQSQHSIDNLAKEVETATGVIEELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTQIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTEETKQSVIQASELSELSNELKQEIDRFKL
>Mature_624_residues
MKLKHKLIGASLLAVIITASALTWLASNQLFEQTRNGVYSRAESVTSAATTGISNWITLKAEIAHAFNDYSQEEDVVSFL
QISRKAGGFDDIFFGTPQGEMFRSHPERNRADYDPRQRPWYQEAQRENKQIITSSYQDAITQSLLVTIAEPVYQNGQFLG
VVGADVLIDQLIDDVISLDAGKDTITMLIDSDGTFLAHPNKALIKKEVNRYFSDMSAQSIQDSISANRIEVANINGSEKL
VYFAKVPNTNWTFAVEMTKETEEAAHSALLREIILLSIVLTVIVAIGVTTLVNLLFRDLIRVSDALAEISSGEGDLTQRL
EPHSDDEVGQLAINFNTFVGNMHSMVCRLRDISVTLANQANSTAEGAEERNVRIQHQMDEINMVATAINEMAAATQEIAG
NADNTAQTAEETVTASNHGAEQVSQSQHSIDNLAKEVETATGVIEELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVEDAQSASASLLQITNSVTQIS
DMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTEETKQSVIQASELSELSNELKQEIDRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=31.1111111111111, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1787690, Length=359, Percent_Identity=27.8551532033426, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788195, Length=290, Percent_Identity=30, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=311, Percent_Identity=27.6527331189711, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789453, Length=339, Percent_Identity=28.6135693215339, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68225; Mature: 68225

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKHKLIGASLLAVIITASALTWLASNQLFEQTRNGVYSRAESVTSAATTGISNWITLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHH
AEIAHAFNDYSQEEDVVSFLQISRKAGGFDDIFFGTPQGEMFRSHPERNRADYDPRQRPW
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
YQEAQRENKQIITSSYQDAITQSLLVTIAEPVYQNGQFLGVVGADVLIDQLIDDVISLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
GKDTITMLIDSDGTFLAHPNKALIKKEVNRYFSDMSAQSIQDSISANRIEVANINGSEKL
CCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
VYFAKVPNTNWTFAVEMTKETEEAAHSALLREIILLSIVLTVIVAIGVTTLVNLLFRDLI
EEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSDALAEISSGEGDLTQRLEPHSDDEVGQLAINFNTFVGNMHSMVCRLRDISVTLANQA
HHHHHHHHHCCCCCCHHHCCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHEEEECCCC
NSTAEGAEERNVRIQHQMDEINMVATAINEMAAATQEIAGNADNTAQTAEETVTASNHGA
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCH
EQVSQSQHSIDNLAKEVETATGVIEELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHH
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVE
HCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCHH
DAQSASASLLQITNSVTQISDMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTEETKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIQASELSELSNELKQEIDRFKL
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLKHKLIGASLLAVIITASALTWLASNQLFEQTRNGVYSRAESVTSAATTGISNWITLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHH
AEIAHAFNDYSQEEDVVSFLQISRKAGGFDDIFFGTPQGEMFRSHPERNRADYDPRQRPW
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
YQEAQRENKQIITSSYQDAITQSLLVTIAEPVYQNGQFLGVVGADVLIDQLIDDVISLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCC
GKDTITMLIDSDGTFLAHPNKALIKKEVNRYFSDMSAQSIQDSISANRIEVANINGSEKL
CCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEE
VYFAKVPNTNWTFAVEMTKETEEAAHSALLREIILLSIVLTVIVAIGVTTLVNLLFRDLI
EEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSDALAEISSGEGDLTQRLEPHSDDEVGQLAINFNTFVGNMHSMVCRLRDISVTLANQA
HHHHHHHHHCCCCCCHHHCCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHEEEECCCC
NSTAEGAEERNVRIQHQMDEINMVATAINEMAAATQEIAGNADNTAQTAEETVTASNHGA
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCH
EQVSQSQHSIDNLAKEVETATGVIEELHHNAQNINTILSTIQNIAEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHH
RAGEQGRGFAVVADEVRILSQRTHASTQEIQQMIETLQGTTQKAVGIMEDSQNLANTSVE
HCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCHH
DAQSASASLLQITNSVTQISDMAAQIAAAAEEQSSVTEEITRNTEAVRDVSNELTEETKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIQASELSELSNELKQEIDRFKL
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]