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The map label for this gene is lnt [H]

Identifier: 59711362

GI number: 59711362

Start: 823271

End: 824785

Strand: Reverse

Name: lnt [H]

Synonym: VF_0755

Alternate gene names: 59711362

Gene position: 824785-823271 (Counterclockwise)

Preceding gene: 59711363

Following gene: 59711360

Centisome position: 28.47

GC content: 41.32

Gene sequence:

>1515_bases
ATGCCTTTACTTTCTCATTACTTTATTCGCCTTCTTGTTGCTTTACTCTCTGGCGCAAGTGCAACCCTTGCTTTCGCTCC
CTACTCTTTATGGGCCTTTGCTTTTATTGCGCCTTTAATCCTTTTATTACTAATGCATAAGCAAACAACCAAAAAAGCCA
CTTGGTTAGGTTTTGTTTGGGGGTTAGGTTACTTTGGTGCAGGCGTGAGTTGGGTTCATGTCAGTATCGATAATTTTGGT
GGTATGCCTGTTGCTGCCAGTCTATTTTTAATGATAGGACTGATCAGCTACCTTTCGTTATATCCAATGCTATTTGCATT
TCTTTTACAGCGATTTTTTAGCAATCACAACATTACAAAGTACTTACTTGCCGCACCAGCTCTTTGGATTATCACCGATT
GGCTTCGTGGTTGGGTATTTACTGGCTTTCCATGGTTATGGCTAGGTTACAGCCAAATTGATAGCCCACTGTCAGCTTGG
GGACCTATTTTAGGTGTAGAAGGCATAACCGTCATGATCCTTCTGTCTGTCGGTACCATGGCATACAGCTTTATTGATAA
GAAATGGGGATTACTGCTTATCCCTGCCGTTATTTTTGCAACCTCTTTTGCCATCAAACCTTTTGATTGGGTTACCCCTC
AACCAGATAAAGCAACTAAAGTTGCGTTGATCCAAGGAAATGTGAACCAAGCAATAAAATGGCTCCCTAGTGAGCGTTGG
CCAACGATCATGAAGTACATGGATTTAACGCGTAAAAATTGGGATGCCGATGTCATTGTATGGCCAGAAGCTGCAATTCC
AGCATTAGAAATCGAAATTCCTAGCTTTCTTCGCAATTTAGATAGCGCAGCAACGATGAATAACAGCACAGTCATCACTG
GTATCGTGGGCCAAAGCCCTACAGGAAATTTCTACAACAATATCATTTCATTAGGTGTTAATGGCACCAATGGATACGAT
TATGGGCAGCAACCTAGATACAGCAAACACCATTTACTTCCATTTGGTGAGTTTGTTCCTTTTGAAAACTTATTACGTCC
AATAGCGCCAATATTTAATCTACCGATGTCATCATTTAGTCGCGGCGATTATATCCAACCAAATATGGAAGCCAGTGGGT
CACATTTAGCGCCCGCATTATGCTATGAAATCGTTTATGGAGAACAAGTGAGAGAAAATATTACCTCTCAAACTGATTAC
ATACTAACGCTTTCAAACGACGCTTGGTTTGGTACCTCTATTGGTCCATTGCAACATATGGAAATGGCCCAAATGCGAGC
TTTAGAAATAGGAAAACCTGTCATCCGCTCAACCAATAATGGAGTTACCGCAATTACGGATCATAAAGGGCAAATAACAA
AACAAATCCCACAGTTCACAACTGCCGTATTACGTGGAGAGGTTATTCCTACTACAGGAACTACCCCTTACCGCTACTGG
GGTTCGATTCCTTTATACTTATTAGTCGGTCTATTTCTGCTTGTTGCTTGGCGTAAACGAAAAGACAATATGTAA

Upstream 100 bases:

>100_bases
AATAACAAAATCAGCCACTGATATTTCAGTGGCTGAACTTTATCTAAATTATACAGACTAACTCTCTTTCGCTACTTACC
ACCTATTTGAGTTATAGCCG

Downstream 100 bases:

>100_bases
TTTCATACGGTCTGTATTTCTTTTATTTTGATATACAGACCTTTAACCAATAGCCTTTTAAACTAAGGTTTTAAAGAAAC
TCTTGTAAATTCTTCATGTT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPLLSHYFIRLLVALLSGASATLAFAPYSLWAFAFIAPLILLLLMHKQTTKKATWLGFVWGLGYFGAGVSWVHVSIDNFG
GMPVAASLFLMIGLISYLSLYPMLFAFLLQRFFSNHNITKYLLAAPALWIITDWLRGWVFTGFPWLWLGYSQIDSPLSAW
GPILGVEGITVMILLSVGTMAYSFIDKKWGLLLIPAVIFATSFAIKPFDWVTPQPDKATKVALIQGNVNQAIKWLPSERW
PTIMKYMDLTRKNWDADVIVWPEAAIPALEIEIPSFLRNLDSAATMNNSTVITGIVGQSPTGNFYNNIISLGVNGTNGYD
YGQQPRYSKHHLLPFGEFVPFENLLRPIAPIFNLPMSSFSRGDYIQPNMEASGSHLAPALCYEIVYGEQVRENITSQTDY
ILTLSNDAWFGTSIGPLQHMEMAQMRALEIGKPVIRSTNNGVTAITDHKGQITKQIPQFTTAVLRGEVIPTTGTTPYRYW
GSIPLYLLVGLFLLVAWRKRKDNM

Sequences:

>Translated_504_residues
MPLLSHYFIRLLVALLSGASATLAFAPYSLWAFAFIAPLILLLLMHKQTTKKATWLGFVWGLGYFGAGVSWVHVSIDNFG
GMPVAASLFLMIGLISYLSLYPMLFAFLLQRFFSNHNITKYLLAAPALWIITDWLRGWVFTGFPWLWLGYSQIDSPLSAW
GPILGVEGITVMILLSVGTMAYSFIDKKWGLLLIPAVIFATSFAIKPFDWVTPQPDKATKVALIQGNVNQAIKWLPSERW
PTIMKYMDLTRKNWDADVIVWPEAAIPALEIEIPSFLRNLDSAATMNNSTVITGIVGQSPTGNFYNNIISLGVNGTNGYD
YGQQPRYSKHHLLPFGEFVPFENLLRPIAPIFNLPMSSFSRGDYIQPNMEASGSHLAPALCYEIVYGEQVRENITSQTDY
ILTLSNDAWFGTSIGPLQHMEMAQMRALEIGKPVIRSTNNGVTAITDHKGQITKQIPQFTTAVLRGEVIPTTGTTPYRYW
GSIPLYLLVGLFLLVAWRKRKDNM
>Mature_503_residues
PLLSHYFIRLLVALLSGASATLAFAPYSLWAFAFIAPLILLLLMHKQTTKKATWLGFVWGLGYFGAGVSWVHVSIDNFGG
MPVAASLFLMIGLISYLSLYPMLFAFLLQRFFSNHNITKYLLAAPALWIITDWLRGWVFTGFPWLWLGYSQIDSPLSAWG
PILGVEGITVMILLSVGTMAYSFIDKKWGLLLIPAVIFATSFAIKPFDWVTPQPDKATKVALIQGNVNQAIKWLPSERWP
TIMKYMDLTRKNWDADVIVWPEAAIPALEIEIPSFLRNLDSAATMNNSTVITGIVGQSPTGNFYNNIISLGVNGTNGYDY
GQQPRYSKHHLLPFGEFVPFENLLRPIAPIFNLPMSSFSRGDYIQPNMEASGSHLAPALCYEIVYGEQVRENITSQTDYI
LTLSNDAWFGTSIGPLQHMEMAQMRALEIGKPVIRSTNNGVTAITDHKGQITKQIPQFTTAVLRGEVIPTTGTTPYRYWG
SIPLYLLVGLFLLVAWRKRKDNM

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=509, Percent_Identity=46.9548133595285, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56378; Mature: 56247

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLSHYFIRLLVALLSGASATLAFAPYSLWAFAFIAPLILLLLMHKQTTKKATWLGFVW
CCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGYFGAGVSWVHVSIDNFGGMPVAASLFLMIGLISYLSLYPMLFAFLLQRFFSNHNITK
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YLLAAPALWIITDWLRGWVFTGFPWLWLGYSQIDSPLSAWGPILGVEGITVMILLSVGTM
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCHHHHCCHHCCCHHHHHHHHHHHHH
AYSFIDKKWGLLLIPAVIFATSFAIKPFDWVTPQPDKATKVALIQGNVNQAIKWLPSERW
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCC
PTIMKYMDLTRKNWDADVIVWPEAAIPALEIEIPSFLRNLDSAATMNNSTVITGIVGQSP
HHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCC
TGNFYNNIISLGVNGTNGYDYGQQPRYSKHHLLPFGEFVPFENLLRPIAPIFNLPMSSFS
CCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHCC
RGDYIQPNMEASGSHLAPALCYEIVYGEQVRENITSQTDYILTLSNDAWFGTSIGPLQHM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHH
EMAQMRALEIGKPVIRSTNNGVTAITDHKGQITKQIPQFTTAVLRGEVIPTTGTTPYRYW
HHHHHHHHHCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
GSIPLYLLVGLFLLVAWRKRKDNM
CCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLLSHYFIRLLVALLSGASATLAFAPYSLWAFAFIAPLILLLLMHKQTTKKATWLGFVW
CCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGYFGAGVSWVHVSIDNFGGMPVAASLFLMIGLISYLSLYPMLFAFLLQRFFSNHNITK
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YLLAAPALWIITDWLRGWVFTGFPWLWLGYSQIDSPLSAWGPILGVEGITVMILLSVGTM
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCHHHHCCHHCCCHHHHHHHHHHHHH
AYSFIDKKWGLLLIPAVIFATSFAIKPFDWVTPQPDKATKVALIQGNVNQAIKWLPSERW
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCC
PTIMKYMDLTRKNWDADVIVWPEAAIPALEIEIPSFLRNLDSAATMNNSTVITGIVGQSP
HHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCC
TGNFYNNIISLGVNGTNGYDYGQQPRYSKHHLLPFGEFVPFENLLRPIAPIFNLPMSSFS
CCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHCC
RGDYIQPNMEASGSHLAPALCYEIVYGEQVRENITSQTDYILTLSNDAWFGTSIGPLQHM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHH
EMAQMRALEIGKPVIRSTNNGVTAITDHKGQITKQIPQFTTAVLRGEVIPTTGTTPYRYW
HHHHHHHHHCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
GSIPLYLLVGLFLLVAWRKRKDNM
CCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]