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The map label for this gene is xni [H]

Identifier: 59711201

GI number: 59711201

Start: 651924

End: 652703

Strand: Reverse

Name: xni [H]

Synonym: VF_0594

Alternate gene names: 59711201

Gene position: 652703-651924 (Counterclockwise)

Preceding gene: 59711202

Following gene: 59711197

Centisome position: 22.53

GC content: 40.77

Gene sequence:

>780_bases
ATGGCAATTCATCTGGTTATTATTGACGCTCTTAATCTTATTCGTCGCGTTCACTCAGCTCAACCTAACCAAGATGATAT
CCAAGCGGTTATCACCACCACCACTCGTACTATTAATAAAATATTAAAAGAAACAGAGCCAACTCATATCATTGCGGTAT
TTGATCATCATCTTCAAGATCGAGGATGGCGTGCAGAAATTCTTCCTCAGTATAAAGAGGACAGAAAACCCATGCCTGAA
GCATTACAGAAAGGCATGGATGATATCCAAGAAGCATGGTGGAAGTTAGGTATTGATTCGCTACTTTCTGATGGCGATGA
AGCGGATGACTTAGTTGCCACCCTAGCCAATAAAGTAGCGATGCATAATGAGCAAGTTACGATCATTTCTACCGATAAAG
GCTACTGTCAGTTACTCTCTCCTACTTTACGTATTCGAGATTATTTTCAACATCGCTGGTTAGATGCTCCTTTTGTAGAA
AAAGAGTTTGGTTTAAAGCCTGAACAATTGGCTGATTACTGGGGATTAGCAGGGATCAGTTCAAGTAAAATCACTGGTAT
TCCGGGGGTCGGCCCAAAAGCAGCGTTAGAAATTCTAACTCAATTCCCAACGATTGAGGCCGCAAACGAGTCTGAAGATC
TACCTAAAAAATACCGTAAGAAATTTGATGAGCATTATGAAACTGCTATTTTATGTCGTCAGGTTGCGGGGTTAAGAACA
GATATTGAGCTTGGGTTTAATTTGCAGGATATACGATATGAGAAAGGGACTAGGGACTAG

Upstream 100 bases:

>100_bases
GATTAAGGCTGGAATTTTTCACCTTCACTAACGTACAATAATAAGCCTATGCAGAATGCGTAGGCTTTTTTCTTTTTTTA
TAGATAGGAATGAATACGTT

Downstream 100 bases:

>100_bases
GGACTAGGGACTACCAAGTATCATGAATATAGTGTGCTTTTCTGCAAAAGAAAGATGGCTATGTTTGATGTGGTTATCAG
AACGATGACAAACAGTTTTT

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MAIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQDRGWRAEILPQYKEDRKPMPE
ALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVAMHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVE
KEFGLKPEQLADYWGLAGISSSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRT
DIELGFNLQDIRYEKGTRD

Sequences:

>Translated_259_residues
MAIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQDRGWRAEILPQYKEDRKPMPE
ALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVAMHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVE
KEFGLKPEQLADYWGLAGISSSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRT
DIELGFNLQDIRYEKGTRD
>Mature_258_residues
AIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQDRGWRAEILPQYKEDRKPMPEA
LQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVAMHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVEK
EFGLKPEQLADYWGLAGISSSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRTD
IELGFNLQDIRYEKGTRD

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI226510970, Length=253, Percent_Identity=51.3833992094862, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1790294, Length=263, Percent_Identity=27.3764258555133, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895 [H]

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 29502; Mature: 29371

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQD
CEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHC
RGWRAEILPQYKEDRKPMPEALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVA
CCCCHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHH
MHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVEKEFGLKPEQLADYWGLAGIS
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCC
SSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIELGFNLQDIRYEKGTRD
CHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
AIHLVIIDALNLIRRVHSAQPNQDDIQAVITTTTRTINKILKETEPTHIIAVFDHHLQD
EEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHC
RGWRAEILPQYKEDRKPMPEALQKGMDDIQEAWWKLGIDSLLSDGDEADDLVATLANKVA
CCCCHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHH
MHNEQVTIISTDKGYCQLLSPTLRIRDYFQHRWLDAPFVEKEFGLKPEQLADYWGLAGIS
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCC
SSKITGIPGVGPKAALEILTQFPTIEAANESEDLPKKYRKKFDEHYETAILCRQVAGLRT
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIELGFNLQDIRYEKGTRD
CHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA