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The map label for this gene is argA

Identifier: 59711192

GI number: 59711192

Start: 643099

End: 644439

Strand: Reverse

Name: argA

Synonym: VF_0585

Alternate gene names: 59711192

Gene position: 644439-643099 (Counterclockwise)

Preceding gene: 59711196

Following gene: 59711186

Centisome position: 22.24

GC content: 40.79

Gene sequence:

>1341_bases
GTGAAGTTTCGTAGTACTGCTTTAGTTAAAGGGTTTCGTCAATCCGCACCTTACGTTAACGCTCATAGAGATAAAACCGT
TGTTATCATGCTTGGTGGAGAAGCGATTGCAGATCCTAACTTCGCTAATATAGTTAATGATATTGCCCTGCTCAACTCGT
TAGGATTACGAATTGTCATTGTATATGGCACTCGTCCTCAGATGCGTTCATTACTAAAACAGACAGAACATCACGCTCCT
TTCCATAAAGGTATACGCATTACCGATGAGCAAACGCTAGAGCTTGTAAAGCAGATAGCTGGACAGTTACAACTCGACAT
CACAGCTCGCCTCTCAATGAGCTTAAACAATACACCAATGGCAGGAGCGCAAATTAACGTTATCAGCGGCAATTTTGTTA
TTGCTCAACCTCTAGGTGTTGATGATGGTATTGATTATTGCCACAGTGGACGTGTCCGTCGAATCGATACCCAAGGGATC
AACCGCATGTTAGATCAACAATCTATTGTTCTACTTGGTCCTGTTGCGAGTTCTGTTACCGGCGAATGTTTTAATCTTTT
ATCAGAAGATGTCGCCACTCAGTTAGCTATCCGCTTAAATGCCGACAAGCTCATTGGTTTCTGTTCAGAGCAAGGTGTTC
TTAATGAAAAAGGACAGATTTTAGCGGAGTTATTTCCAAGTGAAGCTGAAGAGATCCTCCAACGTCTTGAAAAAGAATTA
ACACCAGAAAATGGAAAACTCACGGGCACAATGCGCTTTTTAAAAGGAGCGATATCTGCATGCAAAGCTGGGGTTCCTCG
TAGTCACCTAATTAGCTACAAAGAAGATGGCGCATTAATTCAAGAGTTATTTTCTTTTGATGGTATTGGTACTCAAGTAG
TAATGGCGAGCTCTGAACAAGTTCGTGATGCTGAAATTGATGACATTGGTGGCATATTAGATTTAATTCGCCCATTAGAA
GAAGAAGGCATTTTAGTTCGCCGCTCTCGTGAACAGTTAGAACAAGAGATTGCACAATTTACGATTATTGAAAAAGATGG
ATTAGTTATAGCGTGTGCCGCTTTATATCCTTTCCCTGAAGAAGGAATGGCAGAAATGGGCTGTGTTGCTGTTCATCCTG
ACTATCGAGATGGCGACCGTGGAGTGACTTTACTGAACCGCTTACGCAGTAAAGCAAAACAGTTCAAATTGTCACAGCTC
TTTGTTCTTACCACTCGCAGCCTTCATTGGTTTAGAGAACAAGGTTTTATTGAGGTAGATGTTTCACACTTACCGATAAA
AAAACAGAAACTGTACAACTTTCAGAGAAAATCAAAAATTCTTGTGTTAAAAGGATTATAA

Upstream 100 bases:

>100_bases
AATATTAAGAAAAAGTTATGTGACCTTCTACTAAAGACTTGCGCAATTTAAAATAAATAGTCACAATAAGTGAATAAGTA
TTTATCATGGAAGATATATC

Downstream 100 bases:

>100_bases
AAAAGGCCGCAGAAGGAAATCCCTTTGCGGCCTATTTGTTCTGACTGAATAACTTAAAACTATCCAAGCTTGAGGTTAAT
GACTAATGACCTGCAGTTTT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVIVYGTRPQMRSLLKQTEHHAP
FHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGI
NRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKEL
TPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQVRDAEIDDIGGILDLIRPLE
EEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPEEGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQL
FVLTTRSLHWFREQGFIEVDVSHLPIKKQKLYNFQRKSKILVLKGL

Sequences:

>Translated_446_residues
MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVIVYGTRPQMRSLLKQTEHHAP
FHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGI
NRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKEL
TPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQVRDAEIDDIGGILDLIRPLE
EEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPEEGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQL
FVLTTRSLHWFREQGFIEVDVSHLPIKKQKLYNFQRKSKILVLKGL
>Mature_446_residues
MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVIVYGTRPQMRSLLKQTEHHAP
FHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPMAGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGI
NRMLDQQSIVLLGPVASSVTGECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKEL
TPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQVRDAEIDDIGGILDLIRPLE
EEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPEEGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQL
FVLTTRSLHWFREQGFIEVDVSHLPIKKQKLYNFQRKSKILVLKGL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1789181, Length=443, Percent_Identity=66.1399548532731, Blast_Score=610, Evalue=1e-176,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGA_VIBF1 (Q5E7B6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203968.1
- ProteinModelPortal:   Q5E7B6
- SMR:   Q5E7B6
- STRING:   Q5E7B6
- GeneID:   3277126
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0585
- NMPDR:   fig|312309.3.peg.682
- eggNOG:   COG0548
- HOGENOM:   HBG545264
- OMA:   APYIHAF
- PhylomeDB:   Q5E7B6
- ProtClustDB:   PRK05279
- BioCyc:   VFIS312309:VF0585-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01105
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167
- Gene3D:   G3DSA:3.40.1160.10
- Gene3D:   G3DSA:3.40.630.30
- PIRSF:   PIRSF000423
- TIGRFAMs:   TIGR01890

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1; SSF53633 Aa_kinase; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.1

Molecular weight: Translated: 49489; Mature: 49489

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVI
CCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEE
VYGTRPQMRSLLKQTEHHAPFHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPM
EECCCHHHHHHHHHHHCCCCHHCCEEECCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC
AGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGINRMLDQQSIVLLGPVASSVT
CCCEEEEEECCEEEEECCCCCCCCHHHCCCCEEEECHHHHHHHHCCCCEEEEECCHHHHH
GECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKEL
HHHHHHHHHHHHHHHHEEECHHHHHEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHC
TPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQ
CCCCCCEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCC
VRDAEIDDIGGILDLIRPLEEEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPE
CCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCC
EGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQLFVLTTRSLHWFREQGFIEVD
CCHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCEEEEE
VSHLPIKKQKLYNFQRKSKILVLKGL
CCCCCCHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MKFRSTALVKGFRQSAPYVNAHRDKTVVIMLGGEAIADPNFANIVNDIALLNSLGLRIVI
CCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEE
VYGTRPQMRSLLKQTEHHAPFHKGIRITDEQTLELVKQIAGQLQLDITARLSMSLNNTPM
EECCCHHHHHHHHHHHCCCCHHCCEEECCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCC
AGAQINVISGNFVIAQPLGVDDGIDYCHSGRVRRIDTQGINRMLDQQSIVLLGPVASSVT
CCCEEEEEECCEEEEECCCCCCCCHHHCCCCEEEECHHHHHHHHCCCCEEEEECCHHHHH
GECFNLLSEDVATQLAIRLNADKLIGFCSEQGVLNEKGQILAELFPSEAEEILQRLEKEL
HHHHHHHHHHHHHHHHEEECHHHHHEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHC
TPENGKLTGTMRFLKGAISACKAGVPRSHLISYKEDGALIQELFSFDGIGTQVVMASSEQ
CCCCCCEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCC
VRDAEIDDIGGILDLIRPLEEEGILVRRSREQLEQEIAQFTIIEKDGLVIACAALYPFPE
CCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCC
EGMAEMGCVAVHPDYRDGDRGVTLLNRLRSKAKQFKLSQLFVLTTRSLHWFREQGFIEVD
CCHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCEEEEE
VSHLPIKKQKLYNFQRKSKILVLKGL
CCCCCCHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA