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The map label for this gene is yfiC [C]

Identifier: 59711052

GI number: 59711052

Start: 474338

End: 475042

Strand: Reverse

Name: yfiC [C]

Synonym: VF_0445

Alternate gene names: 59711052

Gene position: 475042-474338 (Counterclockwise)

Preceding gene: 59711054

Following gene: 59711051

Centisome position: 16.39

GC content: 36.31

Gene sequence:

>705_bases
ATGAGCAAAAGCTTTACTTTCAAACAATTTCATATCGATATTGGTTCATGTGGAATGCCAGTTAGTACTGATGGGGTGCT
ATTAGGTGCTTGGGCAGATATTCGTGCGTGTAGCCAAATATTAGATATAGGTGCTGGAACGGGATTATTAAGCCTAATGA
GTGCGCAAAGAAATTCAGATGCACATATTGATGCCATAGAATTAATGCCAATAGCCGCTGACGTTGCTCGTTTAAATTTT
TATCAAAGCCCATGGAAAGAGCGACTCACTCTTATTCATCATGACTTTCTTACTTACCAAGCACCTCATAAATATGACGC
TATTATTTGTAATCCTCCTTATTTTAATAATGGAGAACAATCACAAAAAGGTGAACGTTCTACCGCTCGACATACGGATA
GCCTTCCTTTTGACAAACTATTACAACACTGTAAAACACTGATTTCCCCAACGGGTCGTGCTAGCTTTATTCTTCCAGTA
TTTGAAGGTGAACTTTTTATTAAAGTGGCTAAAAACGATGATTTTCATTTAACCAAAATAACAAAAGTAAAAACTACTGA
AAAAAAATCTCCTACTCGCCTTCTTATCGAGCTATCTCTTTTTCCTCATATTTATCAAGAGAGTACACTCACAATTCACG
ACGGAAATGGATATAGCGACGACTTTATTAAGCTAACTAGAACGTTTTATCTCAATATGGATTAA

Upstream 100 bases:

>100_bases
CAGTAAGTATAAAAACATTTAACAATAGATCCCAAATAGAACAATAAACCAGTTAACAACTTAATTACAAAATTAACAAC
TATGTCCCAATAGGTCTATT

Downstream 100 bases:

>100_bases
AAGATCGGTGATTTATTAGAGATGGATCACTATAATGTCCGGCTGACACTATATTTTTAAAATTTCATACCTGAACGGAG
AATCAACAGTGCTCAAAACG

Product: S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSDAHIDAIELMPIAADVARLNF
YQSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQSQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPV
FEGELFIKVAKNDDFHLTKITKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD

Sequences:

>Translated_234_residues
MSKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSDAHIDAIELMPIAADVARLNF
YQSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQSQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPV
FEGELFIKVAKNDDFHLTKITKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD
>Mature_233_residues
SKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSDAHIDAIELMPIAADVARLNFY
QSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQSQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPVF
EGELFIKVAKNDDFHLTKITKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=235, Percent_Identity=37.8723404255319, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_VIBF1 (Q5E7Q6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_203828.1
- ProteinModelPortal:   Q5E7Q6
- STRING:   Q5E7Q6
- GeneID:   3278094
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_0445
- NMPDR:   fig|312309.3.peg.445
- eggNOG:   COG4123
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- PhylomeDB:   Q5E7Q6
- ProtClustDB:   CLSK874062
- BioCyc:   VFIS312309:VF0445-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR007848
- InterPro:   IPR022882
- PRINTS:   PR00507

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 26383; Mature: 26252

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSD
CCCCCEEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
AHIDAIELMPIAADVARLNFYQSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQ
CCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCC
SQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPVFEGELFIKVAKNDDFHLTKI
CCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCEEEEEE
TKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD
EEEECCCCCCCEEEEEEEECCCHHHCCCEEEEECCCCCCHHHEEEEEEEEEECC
>Mature Secondary Structure 
SKSFTFKQFHIDIGSCGMPVSTDGVLLGAWADIRACSQILDIGAGTGLLSLMSAQRNSD
CCCCEEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
AHIDAIELMPIAADVARLNFYQSPWKERLTLIHHDFLTYQAPHKYDAIICNPPYFNNGEQ
CCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCCC
SQKGERSTARHTDSLPFDKLLQHCKTLISPTGRASFILPVFEGELFIKVAKNDDFHLTKI
CCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCEEEEEE
TKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRTFYLNMD
EEEECCCCCCCEEEEEEEECCCHHHCCCEEEEECCCCCCHHHEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA