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The map label for this gene is bioD [H]

Identifier: 58617619

GI number: 58617619

Start: 1424696

End: 1425367

Strand: Reverse

Name: bioD [H]

Synonym: ERGA_CDS_08920

Alternate gene names: 58617619

Gene position: 1425367-1424696 (Counterclockwise)

Preceding gene: 58617621

Following gene: 58617618

Centisome position: 95.03

GC content: 28.27

Gene sequence:

>672_bases
ATGTCAGCTTATTTTATTACATCATGTGGTACTGGTATAGGTAAAACTTTTATTACTACAGTACTGTGCTGGCATTTACG
AAAAAATTGTAAAACAGTACATGCAATAAAACCTATAATAAGTGGGTGGAATGATGTGGAAATTATGAGTAATGATACAA
GCAAAATATTATGTAGTTTAGATGTGGATTGCAATACTCATAATATCAATAGAATTTCTCCTTGGAGGCTATCTTATCCT
CATGCTCCTAATATAGCTGCTAGGCTGGAAAATATTAAATTAGATTATAATGAAATTTTTAAATTCTGTTATACACATAT
TAATCAAGATATAGATTATCTATTAATAGAAGGTGTTGGTGGTGTTATGTCTCCTATTACTGATCAGAAGACTTGCTTGG
AATTAATACAAGATTTAAAAATAAAAGTAATTTTAGTTATTGGTTCTTACTTAGGGAGCATTAGTCATACATTGACGGTA
CTTAAAGTGTTAGGTGATATTGATGTGAAGATTGTGCTAAGTGTTAACAATAAAACTGATACTAATATTAATGATATAGT
GAAATTTATTTATGAGTATACAGGTAAATTAGTATATGTTCAGCAATATGTTAAAGATAATGCTAACAAATGGGAAAGTA
CTTCAGGTGACATAGTTAATTTTATCTTATAA

Upstream 100 bases:

>100_bases
TCCTTGGTTATCTGTCATAGCTCAATTTTCCTTAGTGTTTTGTTGTGAGTTCAGTGTTTATCAGTTAGTATTAAGTAAAT
TATAAGGTTCACTGTATTAA

Downstream 100 bases:

>100_bases
GGAACAGTAATTGATATTTTTATTAATGTATTACAGTTATTTATATTGTAATTAGTAAATGAATATATATTTAGTAGTAT
ATAGTTAAACCAGTTTATAA

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSAYFITSCGTGIGKTFITTVLCWHLRKNCKTVHAIKPIISGWNDVEIMSNDTSKILCSLDVDCNTHNINRISPWRLSYP
HAPNIAARLENIKLDYNEIFKFCYTHINQDIDYLLIEGVGGVMSPITDQKTCLELIQDLKIKVILVIGSYLGSISHTLTV
LKVLGDIDVKIVLSVNNKTDTNINDIVKFIYEYTGKLVYVQQYVKDNANKWESTSGDIVNFIL

Sequences:

>Translated_223_residues
MSAYFITSCGTGIGKTFITTVLCWHLRKNCKTVHAIKPIISGWNDVEIMSNDTSKILCSLDVDCNTHNINRISPWRLSYP
HAPNIAARLENIKLDYNEIFKFCYTHINQDIDYLLIEGVGGVMSPITDQKTCLELIQDLKIKVILVIGSYLGSISHTLTV
LKVLGDIDVKIVLSVNNKTDTNINDIVKFIYEYTGKLVYVQQYVKDNANKWESTSGDIVNFIL
>Mature_222_residues
SAYFITSCGTGIGKTFITTVLCWHLRKNCKTVHAIKPIISGWNDVEIMSNDTSKILCSLDVDCNTHNINRISPWRLSYPH
APNIAARLENIKLDYNEIFKFCYTHINQDIDYLLIEGVGGVMSPITDQKTCLELIQDLKIKVILVIGSYLGSISHTLTVL
KVLGDIDVKIVLSVNNKTDTNINDIVKFIYEYTGKLVYVQQYVKDNANKWESTSGDIVNFIL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=165, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25181; Mature: 25050

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYFITSCGTGIGKTFITTVLCWHLRKNCKTVHAIKPIISGWNDVEIMSNDTSKILCSL
CCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEE
DVDCNTHNINRISPWRLSYPHAPNIAARLENIKLDYNEIFKFCYTHINQDIDYLLIEGVG
ECCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCC
GVMSPITDQKTCLELIQDLKIKVILVIGSYLGSISHTLTVLKVLGDIDVKIVLSVNNKTD
CHHCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
TNINDIVKFIYEYTGKLVYVQQYVKDNANKWESTSGDIVNFIL
CCHHHHHHHHHHHHCCEEEEHHHHHCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
SAYFITSCGTGIGKTFITTVLCWHLRKNCKTVHAIKPIISGWNDVEIMSNDTSKILCSL
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEE
DVDCNTHNINRISPWRLSYPHAPNIAARLENIKLDYNEIFKFCYTHINQDIDYLLIEGVG
ECCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCC
GVMSPITDQKTCLELIQDLKIKVILVIGSYLGSISHTLTVLKVLGDIDVKIVLSVNNKTD
CHHCCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
TNINDIVKFIYEYTGKLVYVQQYVKDNANKWESTSGDIVNFIL
CCHHHHHHHHHHHHCCEEEEHHHHHCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA