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The map label for this gene is pgsA [H]

Identifier: 58617597

GI number: 58617597

Start: 1389533

End: 1390114

Strand: Reverse

Name: pgsA [H]

Synonym: ERGA_CDS_08700

Alternate gene names: 58617597

Gene position: 1390114-1389533 (Counterclockwise)

Preceding gene: 58617599

Following gene: 58617591

Centisome position: 92.68

GC content: 29.55

Gene sequence:

>582_bases
GTGAAATATAGAACATTATACAGTATGGTTGGTTATTTTAGAAGTACTTTGCCTAATTTATTAACTATATTGCGAGTACT
TGCAATTCCTGCTATAGTTTGTAGCTTTTATATACAAAATGATAGCTCGAATTATATTGCATTTATTATCTTTATTTTCG
CATGTATTACAGATTTTTTCGATGGTTATTTAGCTCGTATATGGCAGACTCAATCTAAGTTTGGTAGGTTGTTTGACCCG
ATTGCAGACAAACTTATTGTATCTGCAACTCTCATTATGTTGGTATATATAGGTAAAGTCACAAAATTGACTATAATACC
TGTTGTTATTATAATTTGTAGAGAAATTCTGATTTCTGGACTGAGGGAATTTCTTATTTCTATGAATTTCAAAATTCCTG
TAATAAAACTAGGGAAAGTTAAGACCTTTATACAAATGGCAGCTATTGCTATGTTAATGTTAGACTACAGTATTATATTA
TATGTTGCAGATATAATATTGTATATAGCTGCAGGGTTAACTGTATATTCTGCATATCTCTATATATGTGTAGCTTTGAG
GCAAATTTATTCTCAGGAATAA

Upstream 100 bases:

>100_bases
GATACGTAAAAGAAAGTTTTACTTGTTAGGTATGCTTACACGTATAATACATCATTTTCAATATAAATATTGAAGTTGTT
GAGATTATCATTATCATAAG

Downstream 100 bases:

>100_bases
AGTTGATCTGTGACATTTTACTATCTTAATGGATTGTATTTTCTTATATGTATTGTTTTTGTGGTAGGTATGATGTTGTT
ATGTCTTGTAAATATTATTT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKYRTLYSMVGYFRSTLPNLLTILRVLAIPAIVCSFYIQNDSSNYIAFIIFIFACITDFFDGYLARIWQTQSKFGRLFDP
IADKLIVSATLIMLVYIGKVTKLTIIPVVIIICREILISGLREFLISMNFKIPVIKLGKVKTFIQMAAIAMLMLDYSIIL
YVADIILYIAAGLTVYSAYLYICVALRQIYSQE

Sequences:

>Translated_193_residues
MKYRTLYSMVGYFRSTLPNLLTILRVLAIPAIVCSFYIQNDSSNYIAFIIFIFACITDFFDGYLARIWQTQSKFGRLFDP
IADKLIVSATLIMLVYIGKVTKLTIIPVVIIICREILISGLREFLISMNFKIPVIKLGKVKTFIQMAAIAMLMLDYSIIL
YVADIILYIAAGLTVYSAYLYICVALRQIYSQE
>Mature_193_residues
MKYRTLYSMVGYFRSTLPNLLTILRVLAIPAIVCSFYIQNDSSNYIAFIIFIFACITDFFDGYLARIWQTQSKFGRLFDP
IADKLIVSATLIMLVYIGKVTKLTIIPVVIIICREILISGLREFLISMNFKIPVIKLGKVKTFIQMAAIAMLMLDYSIIL
YVADIILYIAAGLTVYSAYLYICVALRQIYSQE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=180, Percent_Identity=37.2222222222222, Blast_Score=115, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24650130, Length=129, Percent_Identity=36.4341085271318, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650126, Length=129, Percent_Identity=36.4341085271318, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650128, Length=129, Percent_Identity=36.4341085271318, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22040; Mature: 22040

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRTLYSMVGYFRSTLPNLLTILRVLAIPAIVCSFYIQNDSSNYIAFIIFIFACITDFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DGYLARIWQTQSKFGRLFDPIADKLIVSATLIMLVYIGKVTKLTIIPVVIIICREILISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREFLISMNFKIPVIKLGKVKTFIQMAAIAMLMLDYSIILYVADIILYIAAGLTVYSAYL
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YICVALRQIYSQE
HHHHHHHHHHCCC
>Mature Secondary Structure
MKYRTLYSMVGYFRSTLPNLLTILRVLAIPAIVCSFYIQNDSSNYIAFIIFIFACITDFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DGYLARIWQTQSKFGRLFDPIADKLIVSATLIMLVYIGKVTKLTIIPVVIIICREILISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREFLISMNFKIPVIKLGKVKTFIQMAAIAMLMLDYSIILYVADIILYIAAGLTVYSAYL
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YICVALRQIYSQE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA