Click here to switch to the map view.

The map label for this gene is tcyP [H]

Identifier: 57652641

GI number: 57652641

Start: 455229

End: 456617

Strand: Reverse

Name: tcyP [H]

Synonym: SACOL0454

Alternate gene names: 57652641

Gene position: 456617-455229 (Counterclockwise)

Preceding gene: 57652642

Following gene: 57652639

Centisome position: 16.25

GC content: 39.16

Gene sequence:

>1389_bases
ATGAATGCTTTTCTTACACTGATTAATATTATTGTATTGGTGATTTTCATCGTAATATTGCACATGATGGCTCGCAAACA
TATATCTTTTGCGAAACGTGTGTTTACAGCTTTAGGGATTGGTATAGTATTCGGTGTGTTATTGCATCTTATTTATGGCA
CACATTCGAATGTTATTACATCAACAAGTGACTGGTTCAACATTGTCGGACAAGGTTACGTTGCATTGTTGCAAATGATT
GTTATGCCTTTAATTTTCATTTCTATTGTAGCTGCATTCACTAAAATTCAAATCGGAGAAAAGTTTGCTAAAATTGGTAG
TCTCATTTTTATCTTTTTAATTGGCACTGTCACCATTGCTGCGATTGTTGGTGTTGTGTATGCCTTGGTGTTTGGTTTAG
ATGCATCAACAATTAACCTTGGTAACGCTGAACAAGCACGTGGAAGCGAAATTGCTAAACAAGCGAAAGATTTAACAGCA
CATACGTTACCACAACAAATTTTGGAATTATTGCCTAAAAATCCATTCTTAGATTTCACTGGACAACGTGCAACTTCCAC
GATTGCTGTCGTGATATTTGCTTCGTTTATAGGATTTGCTTATTTACGCGTAGCACGCAAACAACCTGATCATGGTGAAT
TGCTTAAGCGTGCGATTGACGCTATCTATTCACTAGTAATGGCGATTGTGACGTTCGTCTTACGTTTAACGCCATACGGT
GTATTAGCAATTATGGCCAACACATTATCGACAAGTGACTTTGGCGCCATTTGGACTTTAGGAAAATTCTTAATCGCATC
GTACGCTGCATTAATTACGATGTATATCATTCACTTAATTATTTTAAGCCTGTTAGGTATTAGCCCAATTCGCTATGTTA
AAAAGACTTTGGAAGTATTAATCTTTGCATTCACATCACGCTCAAGCGCGGGTGCCTTACCATTGAATGTACAAACACAA
ACAAGACGTCTAGGCGTGCCAGAAGGTATTGCCAATTTCGCTGCGACATTTGGATTGTCGATTGGACAAAATGGTTGTGC
AGGCATTTACCCTGCCATGCTTGCAATTATGGTCGCACCCGTCGCTAATGTAGAAATTGATTTACAATTTATTGTAACGT
TAATCGCTGTCGTGATTATTAGTTCATTCGGCGTTGCTGGCGTCGGTGGCGGGGCTACATTTGCATCCATATTGGTGTTG
TCAACGTTAAACTTGCCAGTCGCTTTAGCCGGCGTGCTCATCTCCGTTGAACCATTGATTGACATGGGTAGAACAGCATT
AAACGTGAACGATTCAATGCTAGCTGGTACAGGTACCGCCAAGTTAACTAAACATTGGGATAAAGATACTTTCGATTCAA
ATGATAATGCTGCATTAACTTCACACTAA

Upstream 100 bases:

>100_bases
TTACATTTAATTGCAAATGCCCTCTTGAAATATTTTAAAATTAATATTATTCTTAGCATACTAGTCGGAATTATATTCAA
AAATTTGAGGAGTGACGTTC

Downstream 100 bases:

>100_bases
TTCATTGCAAGAAATACCCGCCCCCTCTAGCTATACTTATCATTTTAAGCTAGAGGGGGGCGGGTTATTTTGGTATCTTG
CTATCGCTGTATTAAGCCTG

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: Transporter of cystine tcyP [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMI
VMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTA
HTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYG
VLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQ
TRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVL
STLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH

Sequences:

>Translated_462_residues
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMI
VMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTA
HTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYG
VLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQ
TRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVL
STLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>Mature_462_residues
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMI
VMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTA
HTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYG
VLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQ
TRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVL
STLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH

Specific function: Mediates uptake of L-cystine, the oxidized form of L- cysteine [H]

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI5032093, Length=399, Percent_Identity=23.5588972431078, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI223468564, Length=272, Percent_Identity=25.7352941176471, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI223468566, Length=272, Percent_Identity=25.7352941176471, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI169790839, Length=277, Percent_Identity=25.2707581227437, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194239697, Length=451, Percent_Identity=22.1729490022173, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254478, Length=462, Percent_Identity=22.2943722943723, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI21314632, Length=275, Percent_Identity=25.8181818181818, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4827012, Length=225, Percent_Identity=25.7777777777778, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI66773030, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1788024, Length=467, Percent_Identity=50.5353319057816, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1790514, Length=440, Percent_Identity=25, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1789947, Length=436, Percent_Identity=25, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789473, Length=334, Percent_Identity=24.8502994011976, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=472, Percent_Identity=22.0338983050847, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71983106, Length=472, Percent_Identity=22.0338983050847, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193206505, Length=457, Percent_Identity=21.8818380743982, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193206654, Length=449, Percent_Identity=22.71714922049, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17537407, Length=418, Percent_Identity=21.2918660287081, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541374, Length=410, Percent_Identity=21.4634146341463, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583025, Length=463, Percent_Identity=23.7580993520518, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137668, Length=463, Percent_Identity=23.7580993520518, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583023, Length=463, Percent_Identity=23.7580993520518, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 49413; Mature: 49413

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
STSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFT
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAP
HHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLI
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
HCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
STSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFT
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAP
HHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLI
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
HCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA