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The map label for this gene is ahpC

Identifier: 57652639

GI number: 57652639

Start: 453332

End: 453901

Strand: Reverse

Name: ahpC

Synonym: SACOL0452

Alternate gene names: 57652639

Gene position: 453901-453332 (Counterclockwise)

Preceding gene: 57652641

Following gene: 57652638

Centisome position: 16.16

GC content: 37.19

Gene sequence:

>570_bases
ATGTCATTAATTAACAAAGAAATCTTACCATTTACAGCGCAAGCTTTCGATCCAAAAAAAGATCAATTTAAAGAAGTTAC
ACAAGAAGATTTAAAAGGTTCTTGGAGCGTAGTATGCTTCTATCCTGCTGACTTCTCATTCGTTTGTCCAACTGAATTAG
AAGACTTACAAAACCAATATGAAGAATTACAAAAATTAGGCGTAAATGTATTCTCAGTATCAACTGATACTCACTTCGTA
CACAAAGCATGGCATGACCATTCAGATGCAATTAGCAAAATCACTTACACTATGATTGGTGACCCATCACAAACAATCAC
TCGTAATTTTGATGTATTAGATGAAGCTACTGGTTTAGCTCAACGTGGTACATTCATTATCGACCCAGACGGTGTTGTAC
AAGCATCTGAAATTAACGCTGACGGAATTGGCCGTGACGCTAGTACATTAGCTCACAAAATCAAAGCAGCTCAATATGTT
CGTAAAAACCCTGGCGAAGTATGCCCAGCTAAATGGGAAGAAGGCGCTAAAACATTGCAACCTGGTTTAGATTTAGTAGG
TAAAATCTAA

Upstream 100 bases:

>100_bases
AAAATGTAATAATGCTAACTAAGAGATTAGAATTATTATAATTAAGCGCAATCAATTGATAGTTCTAATTCATACTTAAA
TTCTTAGGAGGAAGATATTT

Downstream 100 bases:

>100_bases
GGAGGCATTACAACCATGCTTAATGCTGATTTAAAACAACAACTTAAACAACTATTAGAACTAATGGAGGGCAACGTTGA
ATTCGTTGCCAGCCTTGGTT

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Peroxiredoxin; Thioredoxin peroxidase

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFV
HKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYV
RKNPGEVCPAKWEEGAKTLQPGLDLVGKI

Sequences:

>Translated_189_residues
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFV
HKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYV
RKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>Mature_188_residues
SLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVH
KAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVR
KNPGEVCPAKWEEGAKTLQPGLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Homo sapiens, GI32483377, Length=163, Percent_Identity=38.0368098159509, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI5802974, Length=163, Percent_Identity=38.0368098159509, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI4505591, Length=174, Percent_Identity=36.7816091954023, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI32455266, Length=174, Percent_Identity=36.7816091954023, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI32455264, Length=174, Percent_Identity=36.7816091954023, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI32189392, Length=165, Percent_Identity=37.5757575757576, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI5453549, Length=171, Percent_Identity=34.5029239766082, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI33188454, Length=65, Percent_Identity=49.2307692307692, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786822, Length=189, Percent_Identity=64.5502645502645, Blast_Score=261, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17554494, Length=164, Percent_Identity=38.4146341463415, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193204376, Length=165, Percent_Identity=36.969696969697, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565831, Length=165, Percent_Identity=36.969696969697, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320661, Length=162, Percent_Identity=32.7160493827161, Blast_Score=107, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6323613, Length=165, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357347, Length=169, Percent_Identity=37.8698224852071, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17738015, Length=169, Percent_Identity=36.094674556213, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=36.875, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=36.875, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24656348, Length=164, Percent_Identity=35.3658536585366, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17864676, Length=164, Percent_Identity=35.3658536585366, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24581278, Length=178, Percent_Identity=28.0898876404494, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): AHPC_STAA3 (Q2FJN4)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493094.1
- ProteinModelPortal:   Q2FJN4
- SMR:   Q2FJN4
- STRING:   Q2FJN4
- EnsemblBacteria:   EBSTAT00000036205
- GeneID:   3914843
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_0380
- eggNOG:   COG0450
- GeneTree:   EBGT00050000024736
- HOGENOM:   HBG493509
- OMA:   GDLADHY
- ProtClustDB:   CLSK884603
- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR03137

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: =1.11.1.15

Molecular weight: Translated: 20977; Mature: 20846

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: ACT_SITE 49-49

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQY
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEECCHHHHHHHHHH
EELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLA
HHHHHHCCEEEEECCCCHHHHHHHCCHHHHHHHEEHEEECCCHHHHHCCCHHHHHHCCHH
QRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQ
HCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHH
PGLDLVGKI
CCHHHHCCC
>Mature Secondary Structure 
SLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQY
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEECCHHHHHHHHHH
EELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLA
HHHHHHCCEEEEECCCCHHHHHHHCCHHHHHHHEEHEEECCCHHHHHCCCHHHHHHCCHH
QRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQ
HCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHH
PGLDLVGKI
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA