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The map label for this gene is gpmA [H]

Identifier: 57652634

GI number: 57652634

Start: 449437

End: 450018

Strand: Direct

Name: gpmA [H]

Synonym: SACOL0447

Alternate gene names: 57652634

Gene position: 449437-450018 (Clockwise)

Preceding gene: 57652633

Following gene: 57652640

Centisome position: 16.0

GC content: 32.13

Gene sequence:

>582_bases
ATGACGATTTATTTAGTTAGACATGGCGAATCAAAATCGAATTATGATAATAAACATTTTCGATCTTATTTTTGTGGACA
ATTAGATGTGCCGTTAACGGATACTGGCACAAAAAGTGCAGACGATTTATGTGATTATTTTAAAGAGAAACAGATTAAAC
ATGTATATGTTTCAGACTTATTAAGAACACAGCAAACGTTTGAACATATTTTTCCATATGACATTGCATCAACGACTACC
CCTCTATTAAGAGAACGTTCACTTGGCGTATTTGAGGGTGAATATAAAGATGAAATCAGTGCGAATCCGAAATATGAAAA
ATATTTCAATGATCCAAACTTTAAAGACTTTCGTCATAGTTTTTCACAAAAAGCGCCTGAAGGAGAAAGTTATGAAGATG
TATATCAACGCGTAGAACATTTTATGAATCATGTTGTCAATGAAGATACACAAAAAGATGATATTGTCATTGTTGCACAT
CAAGTTGTCATTCGTTGTTTGATGGTTTATTTTAACAAAGTTTCAAGGGCAGAAGCTGTGGATTTAAAGGTAGAAAATTG
CAAACCATATATCATTGAATAG

Upstream 100 bases:

>100_bases
GAATTAATTCTTTTTTTAGAATAGAATATTAAGATTGATATCGAATTAGTAGTCAAAGTGTTATGGTAGATATGAAATAC
ATAAGGTAAGGAGTAATATT

Downstream 100 bases:

>100_bases
AAGTATAGAGGTTCTGAAAAACTGTGTTTTATAGCGGCCTTCAGAACCTTTTTTTCATTTGGAATTTAAGGGGAATCATT
CTTTTCAACAGACTTACCAC

Product: phosphoglycerate mutase family protein

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTT
PLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAH
QVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE

Sequences:

>Translated_193_residues
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTT
PLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAH
QVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>Mature_192_residues
TIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTP
LLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQ
VVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758902, Length=173, Percent_Identity=32.9479768786127, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI64762445, Length=173, Percent_Identity=32.9479768786127, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI118582286, Length=185, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI64762406, Length=173, Percent_Identity=32.9479768786127, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI224282149, Length=185, Percent_Identity=31.8918918918919, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI4758900, Length=185, Percent_Identity=31.8918918918919, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25145314, Length=175, Percent_Identity=33.7142857142857, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17510917, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71993390, Length=189, Percent_Identity=31.2169312169312, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24643264, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643254, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643260, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643258, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643256, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643262, Length=172, Percent_Identity=30.8139534883721, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643252, Length=172, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17137706, Length=172, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22734; Mature: 22602

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDL
CEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHS
HHHHHHHHHHCCCHHHHCCHHHHHHHCCCCCCCCCHHHCCCCCCHHHHCCCCCHHHHHHH
FSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAV
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHH
DLKVENCKPYIIE
EEEECCCCCEECC
>Mature Secondary Structure 
TIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDL
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHS
HHHHHHHHHHCCCHHHHCCHHHHHHHCCCCCCCCCHHHCCCCCCHHHHCCCCCHHHHHHH
FSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAV
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHH
DLKVENCKPYIIE
EEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11983902 [H]