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The map label for this gene is moaC [H]

Identifier: 57652207

GI number: 57652207

Start: 2329542

End: 2330036

Strand: Direct

Name: moaC [H]

Synonym: SACOL2267

Alternate gene names: 57652207

Gene position: 2329542-2330036 (Clockwise)

Preceding gene: 57650851

Following gene: 57652213

Centisome position: 82.92

GC content: 38.38

Gene sequence:

>495_bases
ATGACTGAGTTTACTCATATTAATCAACAAGGCCACGCCAAAATGGTCGATGTATCAGACAAACAAATTACAAAAAGAAC
TGCTGTCGCTCATTCAAGCATTACTGTAAATGAAACTATTTTTAAGCAGATTTCTAATAACACCAATACCAAAGGCAATG
TATTGAACACTGCTCAAATCGCTGGTATTATGGCTGCCAAAAATACATCAACACTTATTCCGATGTGCCATCCATTACCA
TTGACTGGCATAGATGTTCACTTCAGCTGGGATGAAACAAATGCACCCCTTTATACTTTAAACATTCAAACAACTGTCTC
TACAACTGGCAAAACCGGTGTTGAAATGGAAGCTTTAACCGCTGCATCAGCAACGGCTTTAACCATTTACGACATGACGA
AAGCAGTTGATAAAGGTATGATTATTGGCGAAACCTACCTTGAAAGCAAGTCTGGCGGTAAATCTGGAGATTTTCAACGC
CAATCAAATCAATAA

Upstream 100 bases:

>100_bases
TCTTTAACTGGGATTGGGTTTCTTTTTTCTACTACCATTAAAAATCATCTCCAAAACTTTTATTTTTTCATGATATACTA
GATGCACTAGGAGGGGTAAA

Downstream 100 bases:

>100_bases
ATTATTTTGTAAGCTCATGAATCAGATGATTTAATTCTGGTTTAATGAGCTTTTCTAATGCTAATTTAACTGCGCCTGTT
GATCCTGGAATCGAAAATAT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLP
LTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
QSNQ

Sequences:

>Translated_164_residues
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLP
LTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
QSNQ
>Mature_163_residues
TEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPL
TGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQ
SNQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=164, Percent_Identity=51.219512195122, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=46.7105263157895, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28574490, Length=163, Percent_Identity=46.6257668711656, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574492, Length=150, Percent_Identity=47.3333333333333, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17694; Mature: 17563

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQI
CCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEEHHHH
AGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALT
EEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCEEEEEE
AASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
CCCCEEEEEEHHHHHHHCCEEEEHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQI
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEEEHHHH
AGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALT
EEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCEEEEEE
AASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
CCCCEEEEEEHHHHHHHCCEEEEHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA