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The map label for this gene is mnaA [H]

Identifier: 57652133

GI number: 57652133

Start: 2163782

End: 2164909

Strand: Reverse

Name: mnaA [H]

Synonym: SACOL2103

Alternate gene names: 57652133

Gene position: 2164909-2163782 (Counterclockwise)

Preceding gene: 57652134

Following gene: 57652132

Centisome position: 77.06

GC content: 34.57

Gene sequence:

>1128_bases
ATGAAAAAGATTATGACCATATTTGGAACAAGACCCGAAGCCATAAAGATGGCTCCTTTAGTTAAAGCTTTGGAACAAGA
AAAAATGCTCGAGCCAATTGTTGTTGTTACAGCACAGCATAGAGAAATGCTTGATTCAGTATTAAGTACCTTTGAAATCA
AACCAAAATACGATTTGAATATTATGAAATCAGGACAGACACTTTCTGAGATAACTTCTAAATCAATCACTCAATTAGAA
CAAGTGATTCAATTAGAAAAACCAGACATGGTACTTGTACATGGTGATACGATGACGACATTTGCAGGTGGTTTAGCGGC
ATTTTATAACCAAGTGCCGATTGGACACGTTGAAGCAGGGCTTAGAAGTTATGATAAATATTCACCTTTTCCAGAAGAGG
TGAATAGACAATTAGTTGGTGTATTAGCTGACTTACATTTTGCACCTACTAAAAATGCTGCATCGCATTTGTTAAGTGAA
GGGAAATATTCAGAAAGTGTTGTTGTCACTGGTAATACTGCGATTGATGCTATGAAATATACAGTTGATGACAATTATAA
ATCTAACATCATGGATAAATACCATGACAAAAAATTCATTCTTATGACAGCACACCGACGAGAAAATATCGGGAAACCCA
TGGAAAATATATTTAAAGCGGTTAGACGCTTAATAGATGAGTATACTGATTTAGCACTGGTATATCCAATGCATAAAAAC
CCGAAAGTTCGAGAGGTGGCTCAAAAGATTTTAGGTAGTCATGACAGAATTGAATTGATTGAACCTTTGGACGTAGTAGA
TTTCCATAATTTTGCTAAAAAATCTTATTTTATTTTGACAGATTCAGGTGGAATTCAGGAAGAAGCGCCATCATTTAATA
AGCCAGTTTTAGTTTTGCGAAGTGTTACAGAACGTCCTGAAGGTGTTGAAGCTGGCACATTAAAAGTCATTGGAACAAAT
AAGCAAAATGTGTATCAAGCTGCAAAAGAATTAATCGATGATGAGAGATTATATCATCAAATGTCTGAAGCATCTAATCC
TTACGGTGATGGATTTGCTTCAGAAAGAATAGTTAATCATATTAAGTATTATTTGAATTTAATCACTGAAAAACCAAGCG
ATTTCTGA

Upstream 100 bases:

>100_bases
ATGAAAAGCTAAATGACAAAGCATATATCACACCAGGGTTAGGCGACGCTGGAGATAGATTGTTTGGTACTAAATAGAAG
AATCGGAGATAAGTAGTTTG

Downstream 100 bases:

>100_bases
GGAAAATAGACTTTTTGTCTAATTGTGTCTAAATTGTGTCTAACTATGCTTATTTTTTTACAACAATTTGAATAGAATTG
ACACCACAAATCGCCTATAT

Product: UDP-GlcNAc 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQLE
QVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSE
GKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHKN
PKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGTN
KQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF

Sequences:

>Translated_375_residues
MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQLE
QVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSE
GKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHKN
PKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGTN
KQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF
>Mature_375_residues
MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQLE
QVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSE
GKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHKN
PKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGTN
KQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=50.6775067750677, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42413; Mature: 42413

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLN
CCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCCE
IMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAG
EECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHH
LRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSEGKYSESVVVTGNTAIDAMKY
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHEEE
TVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHKN
EECCCHHHHHHHHHCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCC
PKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLR
CCHHHHHHHHHCCCCCEEHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEE
SVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNH
HHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IKYYLNLITEKPSDF
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREMLDSVLSTFEIKPKYDLN
CCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHEECCCCCCCE
IMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFAGGLAAFYNQVPIGHVEAG
EECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHH
LRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSEGKYSESVVVTGNTAIDAMKY
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHEEE
TVDDNYKSNIMDKYHDKKFILMTAHRRENIGKPMENIFKAVRRLIDEYTDLALVYPMHKN
EECCCHHHHHHHHHCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCC
PKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSYFILTDSGGIQEEAPSFNKPVLVLR
CCHHHHHHHHHCCCCCEEHCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEE
SVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDDERLYHQMSEASNPYGDGFASERIVNH
HHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IKYYLNLITEKPSDF
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]