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The map label for this gene is arsC

Identifier: 57652071

GI number: 57652071

Start: 1880090

End: 1880485

Strand: Direct

Name: arsC

Synonym: SACOL1824

Alternate gene names: 57652071

Gene position: 1880090-1880485 (Clockwise)

Preceding gene: 57652070

Following gene: 57652074

Centisome position: 66.92

GC content: 33.59

Gene sequence:

>396_bases
ATGACTAAAAAAACAATTTATTTTATATGTACAGGCAACTCATGTCGAAGTCAAATGGCTGAAGGTTGGGCTAAACAAAT
CTTAGCGGATGATTGGAATGTATATTCTGCTGGTATCGAAACACACGGTGTTAATCCCAAAGCGATAGAAGCTATGAAAG
AAGTAGGCATTGATATATCAAATCATACATCAGATTTAATCGATAATAATATTATTAAAAATTCAAATTTAGTTGTTACA
TTATGTAGTGATGCAGACGTAAATTGCCCTTCTTTACCAACAAATGTTAAGAAAGAACATTGGGGATTTGATGATCCTGC
AGGCAAGCCTTGGTCAGAGTTCCAACGTGTAAGAGATGAAATTAAAATCGCAATTGAAAATTTCAAATCACGATGA

Upstream 100 bases:

>100_bases
ACTTTAAAACTGGTATCATCATTACAATTCCAGTACTATTTATAACCCTCATAGGGTTGTATCTAACACTTATCATATTT
TAATTAATTAGGAGATTGTT

Downstream 100 bases:

>100_bases
GAGTGGGACAGAAATGATAAAAAAACACTAATGATTTATTATGTAGTGGTTCTTTATCATTAGCTATAACTAATGTGTAC
TTAAAAATAGGAATACATGA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MTKKTIYFICTGNSCRSQMAEGWAKQILADDWNVYSAGIETHGVNPKAIEAMKEVGIDISNHTSDLIDNNIIKNSNLVVT
LCSDADVNCPSLPTNVKKEHWGFDDPAGKPWSEFQRVRDEIKIAIENFKSR

Sequences:

>Translated_131_residues
MTKKTIYFICTGNSCRSQMAEGWAKQILADDWNVYSAGIETHGVNPKAIEAMKEVGIDISNHTSDLIDNNIIKNSNLVVT
LCSDADVNCPSLPTNVKKEHWGFDDPAGKPWSEFQRVRDEIKIAIENFKSR
>Mature_130_residues
TKKTIYFICTGNSCRSQMAEGWAKQILADDWNVYSAGIETHGVNPKAIEAMKEVGIDISNHTSDLIDNNIIKNSNLVVTL
CSDADVNCPSLPTNVKKEHWGFDDPAGKPWSEFQRVRDEIKIAIENFKSR

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARSC_STAA3 (Q2FFW6)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494412.1
- HSSP:   P39155
- ProteinModelPortal:   Q2FFW6
- SMR:   Q2FFW6
- STRING:   Q2FFW6
- EnsemblBacteria:   EBSTAT00000038572
- GeneID:   3914352
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1719
- eggNOG:   COG0394
- GeneTree:   EBGT00050000024620
- HOGENOM:   HBG730979
- OMA:   TVCDGAK
- ProtClustDB:   PRK13530
- HAMAP:   MF_01624
- InterPro:   IPR014064
- InterPro:   IPR017867
- PANTHER:   PTHR11717
- SMART:   SM00226
- TIGRFAMs:   TIGR02691

Pfam domain/function: PF01451 LMWPc; SSF52788 Tyr_Pase_low_mol_wt

EC number: =3.1.3.48

Molecular weight: Translated: 14687; Mature: 14555

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: ACT_SITE 10-10 ACT_SITE 82-82 ACT_SITE 89-89

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKTIYFICTGNSCRSQMAEGWAKQILADDWNVYSAGIETHGVNPKAIEAMKEVGIDIS
CCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
NHTSDLIDNNIIKNSNLVVTLCSDADVNCPSLPTNVKKEHWGFDDPAGKPWSEFQRVRDE
CCCHHHHHCCEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
IKIAIENFKSR
HHHHHHHHCCC
>Mature Secondary Structure 
TKKTIYFICTGNSCRSQMAEGWAKQILADDWNVYSAGIETHGVNPKAIEAMKEVGIDIS
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
NHTSDLIDNNIIKNSNLVVTLCSDADVNCPSLPTNVKKEHWGFDDPAGKPWSEFQRVRDE
CCCHHHHHCCEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
IKIAIENFKSR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA