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The map label for this gene is arsB [H]

Identifier: 57652070

GI number: 57652070

Start: 1878780

End: 1880072

Strand: Direct

Name: arsB [H]

Synonym: SACOL1823

Alternate gene names: 57652070

Gene position: 1878780-1880072 (Clockwise)

Preceding gene: 57652069

Following gene: 57652071

Centisome position: 66.87

GC content: 32.02

Gene sequence:

>1293_bases
ATGATGACAACTTTAGCGACACTCATTTTTCTAGTAACTTTATTATTTGTATTATGGCAACCTAAAGGCCTAGATATTGG
CATTACCGCACTAACTGGTGCCTTTATTGCTGTTATTACTGGTGTTGTAAGTTTTTCCGATGTTTTCGAAGTAACAGGTA
TTGTTTGGAATGCTACTTTGACTTTTGTCTCAGTCATTCTTATTTCATTAATATTAGATAAAGTTGGATTATTCGAATGG
TCAGCTATTCACATGCTTCATGCTTCAAAAGGCAATGGTTTAAAAATGTTCGTTTATATCATATTATTGGGTGCCATTGT
TGCTGCATTTTTCGCAAATGATGGCGCAGCGTTAATCTTAACGCCTATTGTATTAGCGATGGTTAAAAATATAGGTTTTA
GTAAGCGGGCCATATTCCCTTTTATTATTGCGAGTGGTTTTATAGCTGACACAACTTCTTTACCTTTAATCGTGAGCAAT
CTAGTGAATATTATATCTGCTGATTATTTTCATGTAGGATTCGTTCGATATTTTAGTAGAATGATTATACCTAATTTATT
CTCGCTTTTAGCAAGTATTATAGTATTGTGGTTATATTTTAGAAAAGCGATACCTAAAACGTTTGATGATAATAATATAA
AGCATCCTAAAGATGCCATTAATGATTTAAAGCTATTTAAAATTTCATGGATTGTTCTAGTTATATTACTTTTCGGCTAT
CTAATCAGTGAATTTACTAAAATTCCGGTATCAATTTTCACTGGAATCATTGCTTTTATTTTTCTAATGTTGGCTCGTAA
ATCAAATGCTGTAAATATTAAGCAAGTCATTAAGGGCGCACCTTGGAATATAGTATTATTTTCAATTGGTATGTATATCG
TCGTATTCGGCTTAAGAAATGCTGGCATTACTTTAATATTGGCTAAAATATTAGAATATATTTCCAATTACGGTCTATTT
AGCACTATTTTGGGAATGGGCTTCATTTCAGCGTTTTTATCATCAATAATGAATAATATGCCTACAGTTTTAATAGATGC
GATTGCTATTGGTCAATCAAATGTCCATGGCATGTTAAAAGAAGGCCTAATTTATGCGAATGTTATCGGTTCTGATTTAG
GTCCAAAAATTACACCGATAGGCTCTTTAGCTACATTACTGTGGTTACACGTCTTAACACAAAAAGATGTTAAGATTTCT
TGGGGCACATACTTTAAAACTGGTATCATCATTACAATTCCAGTACTATTTATAACCCTCATAGGGTTGTATCTAACACT
TATCATATTTTAA

Upstream 100 bases:

>100_bases
TCAATCATAATATTTTTGAGTCCGTAATTAATAACTTGTCTAAGGTTCATACCTCTAACCAACGATGTATTTGTCATAAC
CTTAAGACTGGTGAATGCTA

Downstream 100 bases:

>100_bases
TTAATTAGGAGATTGTTATGACTAAAAAAACAATTTATTTTATATGTACAGGCAACTCATGTCGAAGTCAAATGGCTGAA
GGTTGGGCTAAACAAATCTT

Product: arsenical pump membrane protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISADYFHVGFVRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIITIPVLFITLIGLYLTLIIF

Sequences:

>Translated_430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISADYFHVGFVRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIITIPVLFITLIGLYLTLIIF
>Mature_430_residues
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEW
SAIHMLHASKGNGLKMFVYIILLGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
LVNIISADYFHVGFVRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKDAINDLKLFKISWIVLVILLFGY
LISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLF
STILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKIS
WGTYFKTGIIITIPVLFITLIGLYLTLIIF

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=423, Percent_Identity=55.5555555555556, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 47273; Mature: 47273

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA