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The map label for this gene is ribE [H]

Identifier: 57652066

GI number: 57652066

Start: 1874278

End: 1874910

Strand: Reverse

Name: ribE [H]

Synonym: SACOL1819

Alternate gene names: 57652066

Gene position: 1874910-1874278 (Counterclockwise)

Preceding gene: 57652067

Following gene: 57652065

Centisome position: 66.74

GC content: 32.7

Gene sequence:

>633_bases
ATGTTTACTGGCATCGTTGAAGAAATAGGTGTCGTTAAAAGTGTTCAAATTCGTCAATCAGTCAGGACGATTGAAATTGA
AGCACATAAGATTACGGCAGATATGCATATTGGTGATTCCATCAGTGTTAATGGTGCATGTTTAACAGTGATTGATTTTA
ATCAGACATCTTTTACTGTTCAAGTAATTAAAGGCACTGAAAATAAAACCTATTTAGCAGATGTTAAGCGACAATCAGAA
GTAAATTTAGAGCGTGCCATGAGTGGTAACGGTAGGTTTGGTGGACATTTTGTCCTCGGTCATGTAGATGAACTAGGAAC
AGTTTCAAAAATAAATGAAACAGCCAATGCAAAAATTATTACGATTCAATGTAGCCAACATATTAATAATCAGTTAGTTA
AGCAAGGGTCTATTACTGTGGATGGTGTTAGTCTAACGGTATTTGATAAGCATGATAACAGTTTTGACATTCATCTTATT
CCAGAAACGAGGCGTTCAACGATTTTATCATCCAAAAAATTAGGAGATAAAGTACATTTAGAAACAGACGTTTTGTTTAA
ATATGTTGAAAATATTTTAAATAAAGATAAAGACCAATTATCTGTAGATAAATTAAGAGCATTTGGTTTTTAG

Upstream 100 bases:

>100_bases
TGATGTGATTGAGATACCAGATGCGAACCAATTTGAAATTGTTCATTCCGAGTTATTAAATCAAAATGTTAAATTAACTT
TACGAAAGAAGTGATGATGC

Downstream 100 bases:

>100_bases
GAGGGGTAGCATGCAATTCGATAATATTGACAGTGCTTTAATGGCTTTAAAAAATGGAGAACCAATTATTGTAGTAGATG
ATGAGAATCGTGAAAATGAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFNQTSFTVQVIKGTENKTYLADVKRQSE
VNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLI
PETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF

Sequences:

>Translated_210_residues
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFNQTSFTVQVIKGTENKTYLADVKRQSE
VNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLI
PETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF
>Mature_210_residues
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFNQTSFTVQVIKGTENKTYLADVKRQSE
VNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLI
PETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=187, Percent_Identity=37.4331550802139, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319733, Length=214, Percent_Identity=37.8504672897196, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23299; Mature: 23299

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFNQTSFTV
CCCCHHHHHCCHHHHHHHHCEEEEEEEEEEEEEEEECCCCEEECCEEEEEEECCCCEEEE
QVIKGTENKTYLADVKRQSEVNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKII
EEEECCCCCEEEEECCCCHHCCHHHHHCCCCCCCCEEEEECCCCCCCHHHCCCCCCEEEE
TIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLIPETRRSTILSSKKLGDKVHL
EEEECCCCCHHHHHCCCEEECCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCEEEE
ETDVLFKYVENILNKDKDQLSVDKLRAFGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFNQTSFTV
CCCCHHHHHCCHHHHHHHHCEEEEEEEEEEEEEEEECCCCEEECCEEEEEEECCCCEEEE
QVIKGTENKTYLADVKRQSEVNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKII
EEEECCCCCEEEEECCCCHHCCHHHHHCCCCCCCCEEEEECCCCCCCHHHCCCCCCEEEE
TIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLIPETRRSTILSSKKLGDKVHL
EEEECCCCCHHHHHCCCEEECCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCEEEE
ETDVLFKYVENILNKDKDQLSVDKLRAFGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]