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The map label for this gene is hrcA [H]

Identifier: 57651975

GI number: 57651975

Start: 1669133

End: 1670110

Strand: Reverse

Name: hrcA [H]

Synonym: SACOL1639

Alternate gene names: 57651975

Gene position: 1670110-1669133 (Counterclockwise)

Preceding gene: 57651976

Following gene: 57651974

Centisome position: 59.45

GC content: 28.63

Gene sequence:

>978_bases
ATGATTACAGATAGGCAATTGAGTATATTAAACGCAATTGTTGAGGATTATGTTGATTTTGGACAACCCGTTGGTTCTAA
AACACTAATTGAGCGACATAACTTGAATGTTAGTCCTGCTACAATTAGAAATGAGATGAAACAGCTTGAAGATTTAAACT
ATATCGAGAAGACACATAGTTCTTCAGGGCGTTCGCCATCACAATTAGGTTTTAGGTATTATGTCAATCGTTTACTTGAA
CAAACATCTCATCAAAAAACAAATAAATTAAGACGATTAAATCAATTGTTAGTTGAGAATCAATATGATGTATCATCAGC
ATTGACATATTTTGCAGATGAATTATCAAATATATCTCAATATACAACTTTAGTTGTTCATCCTAATCATAAACAAGATA
TTATCAATAATGTACACTTGATTCGTGCTAATCCTAATTTAGTTATAATGGTTATCGTATTTTCATCAGGTCATGTTGAG
CATGTACATCTTGCTTCAGACATACCGTTTAATAATGACAAACTAAATACAATATCAAATTTTGTTACAAACAAACTAAC
TGAGTTTAATCAGAATTTACAAGATGATATTGTCTCTTTTGTTCAATCAGAGCAGGAAGAAATTTTTATCAATAAATTGT
TAAATACGATGAATAATCATATTTCTAATCAAAGTAATAGCATTTATATGGGTGGAAAGGTTAAACTTATTGATGCATTG
AATGAAAGTAATGTATCTTCAATTCAGCCCATTCTACAATATATAGAATCAAATAGAATTGCAGAATTATTACAAGATAT
ATCTTCACCAAATATTAATGTAAAAATTGGTAATGAAATTGATGACAGCTTAAGTGATATTTCAATTGTAACAAGTCAAT
ATCATTTTGATGAAACGTTAAAAGGTCAAATCGCTGTGATTGGACCTACAGCTATGCATTATCAAAATGTCATTCAATTA
TTAAATAGAATTTGGTAA

Upstream 100 bases:

>100_bases
AAAAAATTGAAATTTCGAGTCTTTAACATTGACTTACTTTGACCAATTTGATAAATTATAATTAGCACTTGAGATAAGTG
AGTGCTAATGAGGTGAAAAC

Downstream 100 bases:

>100_bases
TGATGGATTAGAAAGTATTGGAGGACAGAAAATGACAAATAAAGACGAATCAGTTAAAAAAAACACTGAATCAACAGTTG
AAGAAACAAACGTCAAACAA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW

Sequences:

>Translated_325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW
>Mature_325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37016; Mature: 37016

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHH
YTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFNNDKLNTISN
HEEEEECCCCHHHHHCCEEEEEECCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHH
FVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECC
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETL
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHC
KGQIAVIGPTAMHYQNVIQLLNRIW
CCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHH
YTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFNNDKLNTISN
HEEEEECCCCHHHHHCCEEEEEECCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHH
FVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECC
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETL
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHC
KGQIAVIGPTAMHYQNVIQLLNRIW
CCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA