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The map label for this gene is cdd [H]

Identifier: 57651961

GI number: 57651961

Start: 1656651

End: 1657055

Strand: Reverse

Name: cdd [H]

Synonym: SACOL1625

Alternate gene names: 57651961

Gene position: 1657055-1656651 (Counterclockwise)

Preceding gene: 57651962

Following gene: 57651960

Centisome position: 58.98

GC content: 35.56

Gene sequence:

>405_bases
ATGAGTTATCAACCTCATTATTTTCAAGAAGTTAGAAAAGCACAACAAGAATCATATTCGCCATACAGTCAATTTAAAGT
AGGGGCTTATTTAAAAACGAAAGACGGTAGAACTTTTTATGGTACCAATGTAGAAAATGCTTCTTATCCATTATCGATAT
GTGCTGAACGAGCTAGTTTGGTATCGGCAATTTCTCAAGGATACAGACCAGGTGATTTTGAATCAATAACTGTAACCGTA
GATGCAGATAAACCGTCATCACCTTGTGGTGCATGTCGTCAAGTTTTGAAGGAATTATGTGATGATGATATGCCTGTGTA
TATGACAAATCATAAAGGAGATATGGTTATGATGACAGTCGCAGAGTTACTACCATTTGGATTTTCAGGAAAGGATTTAG
AATAA

Upstream 100 bases:

>100_bases
ATTGCGGCTTTTAGTGTACTTATAGTTTCAATATTAGCATTTATTATAGGTTTAATAGTATTTTTACCACATTTTATAGC
GTTATTTTAGGGAGGCATAT

Downstream 100 bases:

>100_bases
ATGACAGAACATAAATCAGGATTTGTTTCAATTATAGGTAGACCAAATGTAGGAAAGTCAACATTTGTTAATAGAGTGAT
CGGCCATAAAATAGCAATCA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYPLSICAERASLVSAISQGYRPGDFESITVTV
DADKPSSPCGACRQVLKELCDDDMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE

Sequences:

>Translated_134_residues
MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYPLSICAERASLVSAISQGYRPGDFESITVTV
DADKPSSPCGACRQVLKELCDDDMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE
>Mature_133_residues
SYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYPLSICAERASLVSAISQGYRPGDFESITVTVD
ADKPSSPCGACRQVLKELCDDDMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=124, Percent_Identity=50, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17540514, Length=123, Percent_Identity=44.7154471544715, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551074, Length=122, Percent_Identity=43.4426229508197, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=118, Percent_Identity=43.2203389830509, Blast_Score=100, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24582741, Length=122, Percent_Identity=43.4426229508197, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920920, Length=100, Percent_Identity=41, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582744, Length=96, Percent_Identity=38.5416666666667, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14964; Mature: 14833

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYPLSICAERASL
CCCCCHHHHHHHHHHHHCCCCHHHEEECEEEECCCCCEEECCCCCCCCCHHHHHHHHHHH
VSAISQGYRPGDFESITVTVDADKPSSPCGACRQVLKELCDDDMPVYMTNHKGDMVMMTV
HHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
AELLPFGFSGKDLE
HHHHCCCCCCCCCC
>Mature Secondary Structure 
SYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNVENASYPLSICAERASL
CCCCHHHHHHHHHHHHCCCCHHHEEECEEEECCCCCEEECCCCCCCCCHHHHHHHHHHH
VSAISQGYRPGDFESITVTVDADKPSSPCGACRQVLKELCDDDMPVYMTNHKGDMVMMTV
HHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
AELLPFGFSGKDLE
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]