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The map label for this gene is era

Identifier: 57651960

GI number: 57651960

Start: 1655751

End: 1656650

Strand: Reverse

Name: era

Synonym: SACOL1624

Alternate gene names: 57651960

Gene position: 1656650-1655751 (Counterclockwise)

Preceding gene: 57651961

Following gene: 57651959

Centisome position: 58.97

GC content: 33.22

Gene sequence:

>900_bases
ATGACAGAACATAAATCAGGATTTGTTTCAATTATAGGTAGACCAAATGTAGGAAAGTCAACATTTGTTAATAGAGTGAT
CGGCCATAAAATAGCAATCATGTCCGATAAAGCTCAAACAACTAGAAATAAAATTCAAGGTGTTATGACAAGAGATGACG
CGCAAATTATATTCATTGATACGCCAGGTATTCATAAACCTAAACACAAATTAGGTGACTATATGATGAAAGTCGCTAAA
AATACATTATCTGAGATAGATGCAATCATGTTTATGGTTAATGCCAATGAGGAAATTGGACGAGGCGATGAATATATTAT
AGAAATGTTGAAAAATGTTAAGACACCAGTATTTTTAGTATTAAATAAAATAGATTTAGTGCATCCAGATGAATTAATGC
CAAAGATTGAAGAATATCAAAGTTATATGGACTTTACAGAGATTGTACCTATTTCAGCATTAGAAGGGCTAAATGTCGAT
CATTTTATTGATGTTTTAAAGACGTATTTACCCGAAGGACCTAAATATTATCCAGATGATCAAATTTCAGACCATCCTGA
ACAATTTGTAGTGGGTGAAATCATTCGTGAAAAAATCCTTCATCTTACAAGTGAAGAAATCCCTCATGCGATTGGTGTTA
ATGTGGACCGTATGGTTAAAGAAAGCGAAGATCGTGTTCATATCGAAGCAACTATATATGTTGAAAGAGATTCGCAAAAA
GGAATTGTCATTGGAAAAGGCGGTAAAAAGTTAAAAGAAGTAGGAAAACGTGCGAGACGTGATATAGAAATGCTTCTAGG
CTCTAAAGTTTACTTAGAATTATGGGTCAAAGTTCAAAGAGACTGGCGAAACAAAGTTAACTTTATTCGCCAAATTGGTT
ATGTTGAAGACCAAGATTAA

Upstream 100 bases:

>100_bases
TGATATGCCTGTGTATATGACAAATCATAAAGGAGATATGGTTATGATGACAGTCGCAGAGTTACTACCATTTGGATTTT
CAGGAAAGGATTTAGAATAA

Downstream 100 bases:

>100_bases
TCTTAAAAGTGGTGAAGATAATTGTTAATGCGCCAAAAAGGGATTATCATCAAAGCAGTTGATTATGGTGAATCTGATAA
AATTATCACGATTTTAAATG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAK
NTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQK
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD

Sequences:

>Translated_299_residues
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAK
NTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQK
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
>Mature_298_residues
TEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKN
TLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDH
FIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKG
IVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=24.0625, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=39.7959183673469, Blast_Score=237, Evalue=5e-64,
Organism=Escherichia coli, GI87082120, Length=182, Percent_Identity=30.2197802197802, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646434, Length=313, Percent_Identity=25.2396166134185, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_STAA1 (A7X2W5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442144.1
- ProteinModelPortal:   A7X2W5
- SMR:   A7X2W5
- STRING:   A7X2W5
- EnsemblBacteria:   EBSTAT00000002949
- GeneID:   5560825
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1554
- eggNOG:   COG1159
- GeneTree:   EBGT00050000024727
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   SAUR418127:SAHV_1554-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 34329; Mature: 34198

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFID
CCCCCCCCEEEEECCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHEEECCCEEEEEE
TPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEE
LNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDD
EHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
QISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCEEEEEEEEEEEECCCC
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
CEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFID
CCCCCCCEEEEECCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHEEECCCEEEEEE
TPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEE
LNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDD
EHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
QISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCEEEEEEEEEEEECCCC
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
CEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA