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The map label for this gene is isdA [H]

Identifier: 57651739

GI number: 57651739

Start: 1148029

End: 1149081

Strand: Reverse

Name: isdA [H]

Synonym: SACOL1140

Alternate gene names: 57651739

Gene position: 1149081-1148029 (Counterclockwise)

Preceding gene: 57651749

Following gene: 57651738

Centisome position: 40.9

GC content: 33.62

Gene sequence:

>1053_bases
ATGACAAAACATTATTTAAACAGTAAGTATCAATCAGAACAACGTTCATCAGCTATGAAAAAGATTACAATGGGTACAGC
ATCTATCATTTTAGGTTCCCTTGTATACATAGGCGCAGACAGCCAACAAGTCAATGCGGCAACAGAAGCTACGAACGCAC
CTAATAATCAAAGCACACAAGTTTCTCAAGCAACATCACAACCAATTAATTTCCAAGTGCAAAAAGATGGCTCTTCTGAG
AAGTCACACATGGATGACTATATGCAACACCCTGGTAAAGTAATTAAACAAAATAATAAATATTATTTCCAAACCGTGTT
AAACAATGCATCATTCTGGAAAGAATACAAATTTTACAATGCAAACAATCAAGAATTAGCAACAACTGTTGTTAACGATA
ATAAAAAAGCGGATACTAGAACAATCAATGTTGCAGTTGAACCTGGATATAAGAGCTTAACTACTAAAGTACATATTGTC
GTGCCACAAATTAATTACAATCATAGATATACTACGCATTTGGAATTTGAAAAAGCAATTCCTACATTAGCTGACGCAGC
AAAACCAAACAATGTTAAACCGGTTCAACCAAAACCAGCTCAACCTAAAACACCTACTGAGCAAACTAAACCAGTTCAAC
CTAAAGTTGAAAAAGTTAAACCTACTGTAACTACAACAAGCAAAGTTGAAGACAATCACTCTACTAAAGTTGTAAGTACT
GACACAACAAAAGATCAAACTAAAACACAAACTGCTCATACAGTTAAAACAGCACAAACTGCTCAAGAACAAAATAAAGT
TCAAACACCTGTTAAAGATGTTGCAACAGCGAAATCTGAAAGCAACAATCAAGCTGTAAGTGATAATAAATCACAACAAA
CTAACAAAGTTACAAAACATAACGAAACGCCTAAACAAGCATCTAAAGCTAAAGAATTACCAAAAACTGGTTTAACTTCA
GTTGATAACTTTATTAGCACAGTTGCCTTCGCAACACTTGCCCTTTTAGGTTCATTATCTTTATTACTTTTCAAAAGAAA
AGAATCTAAATAA

Upstream 100 bases:

>100_bases
GAAAATAGATGTGCTAGTATAATTGATAACCATTATCAATTGCAATGGTTAATCATCTCATATAACAACACATAATTTGT
ATCCTTAGGAGGAAAACAAC

Downstream 100 bases:

>100_bases
ATCATCGTCACACTCATAACTTAATATATTTTTTATTTTAAATTTTATTTAACCTATGTCATAGATATTTCATAATATAT
AACATAGGTTATTTTTTTAT

Product: LPXTG cell wall surface anchor protein

Products: NA

Alternate protein names: Fur-regulated protein A; Staphylococcal transferrin-binding protein A [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQVSQATSQPINFQVQKDGSSE
KSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIV
VPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTS
VDNFISTVAFATLALLGSLSLLLFKRKESK

Sequences:

>Translated_350_residues
MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQVSQATSQPINFQVQKDGSSE
KSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIV
VPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTS
VDNFISTVAFATLALLGSLSLLLFKRKESK
>Mature_349_residues
TKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQVSQATSQPINFQVQKDGSSEK
SHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVV
PQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTD
TTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSV
DNFISTVAFATLALLGSLSLLLFKRKESK

Specific function: Transfers its hemin to hemin-free isdC (apo-isdC) directly probably through the activated holo-isdA-apo-isdC complex and driven by the higher affinity of apo-isdC for the cofactor. The reaction is reversible. Binds transferrin, lactoferrin, heme, hemoglob

COG id: COG5386

COG function: function code M; Cell surface protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 NEAT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR006635
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00746 Gram_pos_anchor; PF05031 NEAT [H]

EC number: NA

Molecular weight: Translated: 38742; Mature: 38611

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS50978 NEAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCCCCCH
VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHCCHHHHHHHEEEC
ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
CCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHCEEEEEEEEEECCCCEEEEEEEHHHHC
PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEEEC
DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCCCCCH
VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCEECCCCCEEEEEHHCCHHHHHHHEEEC
ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
CCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHCEEEEEEEEEECCCCEEEEEEEHHHHC
PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEEEC
DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA