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The map label for this gene is cdr [H]

Identifier: 57651662

GI number: 57651662

Start: 981069

End: 982385

Strand: Reverse

Name: cdr [H]

Synonym: SACOL0975

Alternate gene names: 57651662

Gene position: 982385-981069 (Counterclockwise)

Preceding gene: 57651663

Following gene: 57651653

Centisome position: 34.97

GC content: 35.38

Gene sequence:

>1317_bases
ATGCCCAAAATAGTCGTAGTCGGAGCAGTCGCTGGCGGTGCAACATGTGCCAGCCAAATTCGACGTTTAGATAAAGAAAG
TGACATTATTATTTTTGAAAAAGATCGTGATATGAGCTTTGCTAATTGTGCATTGCCTTATGTCATTGGCGAAGTTGTTG
AAGATAGAAGATATGCTTTAGCGTATACACCTGAAGAATTTTATGATAGAAAGCAAATTACAGTAAAAACTTATCATGAA
GTTATTGCAATCAATGATGAAAGACAAACTGTATCTGTATTAAATAGAAAGACAAACGAACAATTTGAAGAATCTTACGA
TAAACTCATTTTAAGCCCTGGTGCAAGTGCAAATAGCCTTGGCTTTGAAAGTGATATTACATTTACACTTAGAAATTTAG
AAGACACTGATGCTATCGATCAATTCATCAAAGCAAATCAAGTTGATAAAGTATTGGTTGTAGGTGCAGGTTATGTTTCA
TTAGAAGTTCTTGAAAATCTTTATGAACGTGGTTTACACCCTACTTTAATTCATCGATCTGATAAGATAAATAAATTAAT
GGATGCCGACATGAATCAACCTATACTTGATGAATTAGATAAGCGGGAGATTCCATACCGTTTAAATGAGGAAATTAATG
CTATCAATGGAAATGAAATTACATTTAAATCAGGAAAAGTTGAACATTACGATATGATTATTGAAGGTGTCGGTACTCAC
CCCAATTCAAAATTTATCGAAAGTTCAAATATCAAACTTGATCGAAAAGGTTTCATACCGGTAAACGATAAATTTGAAAC
AAATGTTCCAAACATTTATGCAATAGGCGATATTGCAACATCACATTATCGACATGTCGATCTACCGGCTAGTGTTCCTT
TAGCTTGGGGCGCTCACCGTGCAGCAAGTATTGTTGCCGAACAAATTGCTGGAAATGACACTATTGAATTCAAAGGCTTC
TTAGGCAACAATATTGTGAAGTTCTTTGATTATACATTTGCGAGTGTCGGCGTTAAACCAAACGAACTAAAGCAATTTGA
CTATAAAATGGTAGAAGTCACTCAAGGTGCACACGCGAATTATTACCCAGGAAATTCCCCTTTACACTTAAGAGTATATT
ATGACACTTCAAACCGTCAGATTTTAAGAGCAGCTGCAGTAGGAAAAGAAGGTGCAGATAAACGTATTGATGTACTATCG
ATGGCAATGATGAACCAGCTAACTGTAGATGAGTTAACTGAGTTTGAAGTGGCTTATGCACCACCATATAGCCACCCTAA
AGATTTAATCAATATGATTGGTTACAAAGCTAAATAA

Upstream 100 bases:

>100_bases
TCGATATTTGAATGATTTCTTTAATTTAAATATTAGATATTACTGTTAATTTATAACTAATCATTTTATAATATTTTAAA
ACAATAGGAGGTAAGTTACG

Downstream 100 bases:

>100_bases
ATGAATCATGCGATTCAATCTAATCTTAATTGTCTAGGTTAGAATTATGTTGGACTGGTACTACTATCCAGTCCATTTTT
TATGTTTAACATTTTTAGAA

Product: coenzyme A disulfide reductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYALAYTPEEFYDRKQITVKTYHE
VIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVS
LEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTH
PNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGF
LGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLS
MAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK

Sequences:

>Translated_438_residues
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYALAYTPEEFYDRKQITVKTYHE
VIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVS
LEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTH
PNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGF
LGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLS
MAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
>Mature_437_residues
PKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYALAYTPEEFYDRKQITVKTYHEV
IAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSL
EVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTHP
NSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFL
GNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSM
AMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=321, Percent_Identity=28.3489096573209, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI21389617, Length=321, Percent_Identity=28.3489096573209, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226437568, Length=321, Percent_Identity=28.3489096573209, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559934, Length=403, Percent_Identity=23.5732009925558, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281359715, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281359713, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24639250, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI18543267, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24639252, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24639257, Length=292, Percent_Identity=25.6849315068493, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24585130, Length=288, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49291; Mature: 49160

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYAL
CCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEE
AYTPEEFYDRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSL
EECCHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCC
GFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRS
CCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECC
DKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTH
HHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCEEEEEEEEECCCC
PNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHR
CCCCCEECCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHH
AASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHAN
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCEEEEEEECCCCCC
YYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYA
CCCCCCCEEEEEEEECCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCEEEEEC
PPYSHPKDLINMIGYKAK
CCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
PKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRRYAL
CCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEE
AYTPEEFYDRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSL
EECCHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCC
GFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRS
CCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECC
DKINKLMDADMNQPILDELDKREIPYRLNEEINAINGNEITFKSGKVEHYDMIIEGVGTH
HHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCEEEEEEEEECCCC
PNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHR
CCCCCEECCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHH
AASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHAN
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCEEEEEEECCCCCC
YYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYA
CCCCCCCEEEEEEEECCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCEEEEEC
PPYSHPKDLINMIGYKAK
CCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA