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The map label for this gene is sglT [H]

Identifier: 57651238

GI number: 57651238

Start: 345545

End: 347077

Strand: Reverse

Name: sglT [H]

Synonym: SACOL0311

Alternate gene names: 57651238

Gene position: 347077-345545 (Counterclockwise)

Preceding gene: 57651239

Following gene: 57651230

Centisome position: 12.35

GC content: 36.01

Gene sequence:

>1533_bases
ATGAAAGAAGTTGGATTTGGCACACTAAACTGGGTTGCCGTTATCATTTATCTACTAGCTATGTTGTTCATTGGCGTTTA
TTTTACCAAGCGCGCGAGCCAAAGTACCAATAGTTTCTTTACCGCAAGTGGTCGCTTGCCATCTTGGGTAGTTGGCTTTT
CAATTTATGCTACTACGTTAAGTGCGATTACATTTATGTCGACACCAGAGAAAGCATTTTTAACAGATTGGTCATATATC
GCTGGTAACATTGCTATCGTCGCAATTATTCCATTACTTATTTATTTCTATGTCCCTTTCTTTAAAAAGTTAAAGGTAAC
ATCTGCATATGAATATTTAGAAGCTAGATTTGGCCCTAGCATACGTGTCATTGGCTCATTATTATTTGTCGTTTACCATT
TAGGGCGTGTTGCAATTGTTATCTACTTACCAACATTAGCAATCACATCTGTATCAGACATGAACCCTTATATCGTTGCA
TCACTCGTTGGTTTACTATGTATTTTATATACATTTTTAGGTGGTTTCGAAGGTGTGGTTTGGAGTGATTTCATTCAAGG
CGTCATTTTATTAGGCGGCGCTTTAGTTATTATTATTCTAGGTGTTGTGAACATTAAAGGCGGTTTCGGCACTGTCTTTG
CAGATGCGATTGAGCACAAAAAATTAATTAGTGCAGACAATTGGAAACTAAATACTGCGGCAGCTGCCATTCCAATTATT
TTCCTAGGAAATATTTTCAACAACTTGTATCAATACACAGCGAGTCAAGACGTCGTGCAGCGTTATCAAGCTTCTGATAG
TTTAAAAGAAACAAATAAATCGTTATGGACAAATGGTATCCTAGCTTTAATTTCAGCACCCTTATTTTATGGTATGGGTA
CAATGCTGTATTCATTTTATACACATGAAGCTGTTTTACCAAAAGGCTTCAATACATCATCTGTAGTGCCATATTTCATT
TTGACTGAGATGCCACCATTTGTAGCAGGATTACTTATTGCAGCCATTTTCGCCGCTGCACAGTCTACCATTTCATCTAG
TTTAAATTCTATATCTGCTTGTATTTCAATCGACATTAAGCAACGCTTCTTCGGAAAAGGTAGCGAGCGACACGAAGTTA
ACTTTGCACGTTTCATTATTATCATTGCAGGTATTTTCGGTTTTGGAATGTCACTATACTTAATTGCTTCTAATTCAAAT
GACTTATGGGATTTATTCTTGTTTGTGACTGGATTATTCGGCGTTCCATTGGCTGGTGTATTTGCAGTTGGTATTTTCAC
TAAACGTACGAATACATTCGGTGTTATTTGTGGATTAATATTGGGTATCATCTTTGCTTATGTCTATAATGGTGTTGGCA
AAGGTAACTCACCTTTCTATGTATCTACCATTTCATTTACAGTTGCTTTTGTCTTTGCTTATATACTTAGCTTCATTGTC
CCTTCAAAACATAAAAAAGATATAACGGGATTAACAATTTTTGAAAAAGATAAACCATCAACATACATTTCAAAAACGGC
TACGAAAAAGTAG

Upstream 100 bases:

>100_bases
ACCTTTTAACGAAGCACATCGACAAACATTAGATCAACTCATTGCAAAATACGATTTATAGACATCAAAGAATCAATACA
TTGTAAAGGGGATGTTGCCC

Downstream 100 bases:

>100_bases
ATTGTTATGATAAAACCCCGTCACTAAGTTATGATGCGCTGTTGCGCCAACTTGGTGACGGGGTTTAGCTTTGCCATGAA
TTTAATTTAGGTACTTCGAT

Product: sodium:solute symporter family protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKEVGFGTLNWVAVIIYLLAMLFIGVYFTKRASQSTNSFFTASGRLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYI
AGNIAIVAIIPLLIYFYVPFFKKLKVTSAYEYLEARFGPSIRVIGSLLFVVYHLGRVAIVIYLPTLAITSVSDMNPYIVA
SLVGLLCILYTFLGGFEGVVWSDFIQGVILLGGALVIIILGVVNIKGGFGTVFADAIEHKKLISADNWKLNTAAAAIPII
FLGNIFNNLYQYTASQDVVQRYQASDSLKETNKSLWTNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFNTSSVVPYFI
LTEMPPFVAGLLIAAIFAAAQSTISSSLNSISACISIDIKQRFFGKGSERHEVNFARFIIIIAGIFGFGMSLYLIASNSN
DLWDLFLFVTGLFGVPLAGVFAVGIFTKRTNTFGVICGLILGIIFAYVYNGVGKGNSPFYVSTISFTVAFVFAYILSFIV
PSKHKKDITGLTIFEKDKPSTYISKTATKK

Sequences:

>Translated_510_residues
MKEVGFGTLNWVAVIIYLLAMLFIGVYFTKRASQSTNSFFTASGRLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYI
AGNIAIVAIIPLLIYFYVPFFKKLKVTSAYEYLEARFGPSIRVIGSLLFVVYHLGRVAIVIYLPTLAITSVSDMNPYIVA
SLVGLLCILYTFLGGFEGVVWSDFIQGVILLGGALVIIILGVVNIKGGFGTVFADAIEHKKLISADNWKLNTAAAAIPII
FLGNIFNNLYQYTASQDVVQRYQASDSLKETNKSLWTNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFNTSSVVPYFI
LTEMPPFVAGLLIAAIFAAAQSTISSSLNSISACISIDIKQRFFGKGSERHEVNFARFIIIIAGIFGFGMSLYLIASNSN
DLWDLFLFVTGLFGVPLAGVFAVGIFTKRTNTFGVICGLILGIIFAYVYNGVGKGNSPFYVSTISFTVAFVFAYILSFIV
PSKHKKDITGLTIFEKDKPSTYISKTATKK
>Mature_510_residues
MKEVGFGTLNWVAVIIYLLAMLFIGVYFTKRASQSTNSFFTASGRLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYI
AGNIAIVAIIPLLIYFYVPFFKKLKVTSAYEYLEARFGPSIRVIGSLLFVVYHLGRVAIVIYLPTLAITSVSDMNPYIVA
SLVGLLCILYTFLGGFEGVVWSDFIQGVILLGGALVIIILGVVNIKGGFGTVFADAIEHKKLISADNWKLNTAAAAIPII
FLGNIFNNLYQYTASQDVVQRYQASDSLKETNKSLWTNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFNTSSVVPYFI
LTEMPPFVAGLLIAAIFAAAQSTISSSLNSISACISIDIKQRFFGKGSERHEVNFARFIIIIAGIFGFGMSLYLIASNSN
DLWDLFLFVTGLFGVPLAGVFAVGIFTKRTNTFGVICGLILGIIFAYVYNGVGKGNSPFYVSTISFTVAFVFAYILSFIV
PSKHKKDITGLTIFEKDKPSTYISKTATKK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI167466278, Length=433, Percent_Identity=30.9468822170901, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI256985183, Length=446, Percent_Identity=27.3542600896861, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI157671931, Length=459, Percent_Identity=26.5795206971678, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI4507035, Length=446, Percent_Identity=28.9237668161435, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI206597483, Length=534, Percent_Identity=23.0337078651685, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI206597487, Length=461, Percent_Identity=24.0780911062907, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI109659836, Length=463, Percent_Identity=22.4622030237581, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI109659839, Length=482, Percent_Identity=22.4066390041494, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI17941285, Length=540, Percent_Identity=22.5925925925926, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI14140236, Length=510, Percent_Identity=21.5686274509804, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI110835708, Length=543, Percent_Identity=21.731123388582, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4507031, Length=461, Percent_Identity=23.4273318872017, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1790113, Length=476, Percent_Identity=23.9495798319328, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787251, Length=383, Percent_Identity=23.7597911227154, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115533094, Length=464, Percent_Identity=24.7844827586207, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566512, Length=366, Percent_Identity=24.8633879781421, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533096, Length=323, Percent_Identity=24.1486068111455, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221459588, Length=428, Percent_Identity=27.5700934579439, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573698, Length=473, Percent_Identity=29.1754756871036, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24651739, Length=465, Percent_Identity=27.741935483871, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24645928, Length=440, Percent_Identity=27.0454545454545, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI221459584, Length=417, Percent_Identity=28.0575539568345, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221459586, Length=428, Percent_Identity=26.4018691588785, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24640370, Length=385, Percent_Identity=29.3506493506493, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24651741, Length=440, Percent_Identity=27.0454545454545, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221459582, Length=406, Percent_Identity=29.8029556650246, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161076631, Length=418, Percent_Identity=27.9904306220096, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28574994, Length=445, Percent_Identity=26.5168539325843, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281362918, Length=456, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641117, Length=477, Percent_Identity=25.9958071278826, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24650192, Length=369, Percent_Identity=24.390243902439, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281364280, Length=473, Percent_Identity=26.215644820296, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19920916, Length=424, Percent_Identity=27.8301886792453, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221379702, Length=414, Percent_Identity=26.3285024154589, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281362054, Length=474, Percent_Identity=25.5274261603376, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281362052, Length=474, Percent_Identity=25.5274261603376, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281362050, Length=474, Percent_Identity=25.5274261603376, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24648056, Length=474, Percent_Identity=25.5274261603376, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21356827, Length=474, Percent_Identity=25.5274261603376, Blast_Score=119, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55814; Mature: 55814

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCEEEEECCCCCHHHHHCCCCC
>Mature Secondary Structure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CCCCCCCCCCEEEEECCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]