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The map label for this gene is fnbB [H]

Identifier: 57651008

GI number: 57651008

Start: 2565936

End: 2568758

Strand: Reverse

Name: fnbB [H]

Synonym: SACOL2509

Alternate gene names: 57651008

Gene position: 2568758-2565936 (Counterclockwise)

Preceding gene: 57651009

Following gene: 57651007

Centisome position: 91.43

GC content: 36.34

Gene sequence:

>2823_bases
GTGAAAAGCAATCTTAGATACGGCATAAGAAAACACAAATTGGGAGCGGCCTCAGTATTCTTAGGAACAATGATCGTTGT
TGGAATGGGACAAGAAAAAGAAGCTGCAGCATCGGAACAAAACAATACTACAGTAGAGGAAAGTGGGAGTTCAGCTACTG
AAAGTAAAGCAAGCGAAACACAAACAACTACAAATAACGTTAATACAATAGATGAAACACAATCATACAGCGCGACATCA
ACTGAGCAACCATCACAATCAACACAAGTAACAACAGAAGAAGCACCGAAAACTGTGCAAGCACCAAAAGTAGAAACTTC
GCGAGTTGATTTGCCATCGGAAAAAGTTGCTGATAAGGAAACTACAGGAACTCAAGTTGACATAGCTCAACCAAGTAACG
TCTCAGAAATTAAACCAAGAATGAAAAGATCAACTGACGTTACAGCAGTTGCAGAGAAAGAAGTAGTGGAAGAAACTAAA
GCGACAGGTACAGATGTAACAAATAAAGTGGAAGTAGAAGAAGGTAGTGAAATTGTAGGACATAAACAAGATACGAATGT
TGTAAATCCTCATAACGCAGAAAGAGTAACCTTGAAATATAAATGGAAATTTGGAGAAGGAATTAAGGCGGGAGATTATT
TTGATTTCACATTAAGCGATAATGTTGAAACTCATGGTATCTCAACACTGCGTAAAGTTCCGGAGATAAAAAGTACAGAT
GGTCAAGTTATGGCGACAGGAGAAATAATTGGAGAAAGAAAAGTTAGATATACGTTTAAAGAATATGTACAAGAAAAGAA
AGATTTAACTGCTGAATTATCTTTAAATCTATTTATTGATCCTACAACAGTGACGCAAAAAGGTAACCAAAATGTTGAAG
TTAAATTGGGTGAGACTACGGTTAGCAAAATATTTAATATTCAATATTTAGGTGGAGTTAGAGATAATTGGGGAGTAACA
GCTAATGGTCGAATTGATACTTTAAATAAAGTAGATGGGAAATTTAGTCATTTTGCGTACATGAAACCTAACAACCAGTC
GTTAAGCTCTGTGACAGTAACTGGTCAAGTAACTAAAGGAAATAAACCAGGGGTTAATAATCCAACAGTTAAGGTATATA
AACACATTGGTTCAGACGATTTAGCTGAAAGCGTATATGCAAAGCTTGATGATGTCAGCAAATTTGAAGATGTGACTGAT
AATATGAGTTTAGATTTTGATACTAATGGTGGTTATTCTTTAAACTTTAATAATTTAGACCAAAGTAAAAATTATGTAAT
AAAATATGAAGGGTATTATGATTCAAATGCTAGCAACTTAGAATTTCAAACACACCTTTTTGGATATTATAACTATTATT
ATACAAGTAATTTAACTTGGAAAAATGGCGTTGCATTTTACTCTAATAACGCTCAAGGCGACGGCAAAGATAAACTAAAG
GAACCTATTATAGAACATAGTACTCCTATCGAACTTGAATTTAAATCAGAGCCGCCAGTGGAGAAGCATGAATTGACTGG
TACAATCGAAGAAAGTAATGATTCTAAGCCAATTGATTTTGAATATCATACAGCTGTTGAAGGTGCAGAAGGTCATGCAG
AAGGTACCATTGAAACTGAAGAAGATTCTATTCATGTAGACTTTGAAGAATCGACACATGAAAATTCAAAACATCATGCT
GATGTTGTTGAATATGAAGAAGATACAAACCCAGGTGGTGGTCAGGTTACTACTGAGTCTAACCTAGTTGAATTTGACGA
AGATTCTACAAAAGGTATTGTAACTGGTGCTGTTAGCGATCATACAACAATTGAAGATACGAAAGAATATACGACTGAAA
GTAATCTGATTGAACTAGTAGATGAACTACCTGAAGAACATGGTCAAGCGCAAGGACCAATCGAGGAAATTACTGAAAAC
AATCATCATATTTCTCATTCTGGTTTAGGAACTGAAAATGGTCACGGTAATTATGGCGTGATTGAAGAAATCGAAGAAAA
TAGCCACGTGGATATTAAGAGTGAATTAGGTTACGAAGGTGGCCAAAATAGCGGTAATCAGTCATTTGAGGAAGACACAG
AAGAAGATAAACCGAAATATGAACAAGGTGGCAATATCGTAGATATCGATTTCGATAGTGTACCTCAAATTCATGGTCAA
AATAATGGTAACCAATCATTCGAAGAAGATACAGAGAAAGACAAACCTAAGTATGAACAAGGTGGTAATATCATTGATAT
CGACTTCGACAGTGTGCCACATATTCACGGATTCAATAAGCACACTGAAATTATTGAAGAAGATACAAATAAAGATAAAC
CAAATTATCAATTCGGTGGACACAATAGTGTTGACTTTGAAGAAGATACACTTCCACAAGTAAGTGGTCATAATGAAGGT
CAACAAACGATTGAAGAAGATACAACACCTCCAATCGTGCCACCAACGCCACCGACACCAGAAGTACCAAGCGAGCCGGA
AACACCAACACCACCGACACCAGAAGTACCAAGCGAGCCGGAAACACCAACACCGCCAACGCCAGAGGTACCAACTGAAC
CTGGTAAACCAATACCACCTGCTAAAGAAGAACCTAAAAAACCTTCTAAACCAGTGGAACAAGGTAAAGTAGTAACACCT
GTTATTGAAATCAATGAAAAGGTTAAAGCAGTGGTACCAACTAAAAAAGCACAATCTAAGAAATCTGAACTACCTGAAAC
AGGTGGAGAAGAATCAACAAACAACGGCATGTTGTTCGGCGGATTATTTAGCATTTTAGGTTTAGCGTTATTACGCAGAA
ATAAAAAGAATCACAAAGCATAA

Upstream 100 bases:

>100_bases
ACTCGCTTTTTTTCATTGCTTTTAAAAACCGAACAATATAGAATTGCATTTATTGAGTTTTAAAAATAAATGAATTTTGC
ATTTAAGGGAGAATATTATA

Downstream 100 bases:

>100_bases
TCAATCCAAAATTGACAGGTTTATTTCATAAATTATATGAAGTAAGCCTGTTTTTTAAAATTAAAACAAATTTCCCAAGA
AATAATTACATACTCAATGA

Product: fibronectin binding protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 940; Mature: 940

Protein sequence:

>940_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQ
NNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPQVSGHNEG
QQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTP
VIEINEKVKAVVPTKKAQSKKSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA

Sequences:

>Translated_940_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQ
NNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPQVSGHNEG
QQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTP
VIEINEKVKAVVPTKKAQSKKSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA
>Mature_940_residues
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSATS
TEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKETTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETK
ATGTDVTNKVEVEEGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETTVSKIFNIQYLGGVRDNWGVT
ANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKGNKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTD
NMSLDFDTNGGYSLNFNNLDQSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHA
DVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITEN
NHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQ
NNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPQVSGHNEG
QQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTP
VIEINEKVKAVVPTKKAQSKKSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA

Specific function: Promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin. This confers to S.aureus the ability to invade endothelial cells. Promotes adherence to and aggregation of activated platel

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011266
- InterPro:   IPR008966
- InterPro:   IPR011252
- InterPro:   IPR004237
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02986 Fn_bind; PF00746 Gram_pos_anchor; PF10425 SdrG_C_C; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 103556; Mature: 103556

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASET
CCCCCCCCHHHHCCCHHHHHHHHHHHEECCCCHHHHHCCCCCCCHHCCCCCHHHHHHHHH
QTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETKATGTDVTNKVEVEEGSEIVG
CCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
HKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETT
CCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEECCCCCEEEEEECCHH
VSKIFNIQYLGGVRDNWGVTANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKG
HHHHEEEEEECCCCCCCCEEECCCCCCHHHCCCCCCEEEEECCCCCCCCEEEEEEEEECC
NKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTDNMSLDFDTNGGYSLNFNNLD
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCC
QSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
CCCCEEEEECCEECCCCCCCEEEEEEEEEEEEEEECCCEECCCEEEEECCCCCCCHHHHH
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETE
HHHHHCCCCEEEEECCCCCCCHHHCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEC
EDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSD
CCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCEEECCCCCCEEEEECCCC
HTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCH
IEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQ
HHHHCCCCCEEEHHHCCCCCCCCCCCCCCHHCCHHCCCHHHHCCCEEEECCCCCCCCCCC
NNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGG
CCCCCCCHHHHHHCCCCHHHCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
HNSVDFEEDTLPQVSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEP
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVVPTKKAQSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEEEECCCCEEEECCCHHHHHH
KSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA
HHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASET
CCCCCCCCHHHHCCCHHHHHHHHHHHEECCCCHHHHHCCCCCCCHHCCCCCHHHHHHHHH
QTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPKTVQAPKVETSRVDLPSEKVADKE
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TTGTQVDIAQPSNVSEIKPRMKRSTDVTAVAEKEVVEETKATGTDVTNKVEVEEGSEIVG
CCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
HKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSTD
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
GQVMATGEIIGERKVRYTFKEYVQEKKDLTAELSLNLFIDPTTVTQKGNQNVEVKLGETT
CCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEECCCCCEEEEEECCHH
VSKIFNIQYLGGVRDNWGVTANGRIDTLNKVDGKFSHFAYMKPNNQSLSSVTVTGQVTKG
HHHHEEEEEECCCCCCCCEEECCCCCCHHHCCCCCCEEEEECCCCCCCCEEEEEEEEECC
NKPGVNNPTVKVYKHIGSDDLAESVYAKLDDVSKFEDVTDNMSLDFDTNGGYSLNFNNLD
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCC
QSKNYVIKYEGYYDSNASNLEFQTHLFGYYNYYYTSNLTWKNGVAFYSNNAQGDGKDKLK
CCCCEEEEECCEECCCCCCCEEEEEEEEEEEEEEECCCEECCCEEEEECCCCCCCHHHHH
EPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGTIETE
HHHHHCCCCEEEEECCCCCCCHHHCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEC
EDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSD
CCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCEEECCCCCCEEEEECCCC
HTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCH
IEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQ
HHHHCCCCCEEEHHHCCCCCCCCCCCCCCHHCCHHCCCHHHHCCCEEEECCCCCCCCCCC
NNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGG
CCCCCCCHHHHHHCCCCHHHCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
HNSVDFEEDTLPQVSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEP
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ETPTPPTPEVPTEPGKPIPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVVPTKKAQSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEEEECCCCEEEECCCHHHHHH
KSELPETGGEESTNNGMLFGGLFSILGLALLRRNKKNHKA
HHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA