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The map label for this gene is bioW

Identifier: 57650968

GI number: 57650968

Start: 2482517

End: 2483209

Strand: Reverse

Name: bioW

Synonym: SACOL2424

Alternate gene names: 57650968

Gene position: 2483209-2482517 (Counterclockwise)

Preceding gene: 57650969

Following gene: 57650967

Centisome position: 88.39

GC content: 33.33

Gene sequence:

>693_bases
ATGTATAGTATAAAAATGCGTTCTAGCAATCAAGATGTTCATATTAGTGGTGCTGAAACGATTTGTGAGTTTGACAAAAT
AGAACAGACGGTACAAAGGTTTTATAATAAAGGTTTTTTTCATGAAAATGGGCAACCGGATTTTCTCAATATAAAAATAC
AAAAAATCATGGAACCGATTCAACAAATAAAAGCACTACAAATTATTGAGGATGATAAAGCAAATCTCCAACATTTAACA
CAAGAATGTGGTGTCACTGAACAAGCGCTAAATCAAGGGATGACATATATTAAAAATGAAACGGTTTATACAGGAGCTAT
TATTCTATCTGCTATATCTGGTAAACGTTTAGATTCATTTGGACAAAGGGGGATTAGGGCAACACATTTTTCGTTTGAAG
ATATAAATAATAAAGGTGATCTTAATGAAAGAGTGACTGATGCCTTAGCAATTGCTAGTTGTATCAATGCGCATCCGTAT
GTCAAAGGAGAACTTTGCGTGTCCGATGACTTAACGTATACGACAGGTTATTTTGCCGCTGCTAAAATTGGTTACCATCG
ATTATTTGATATTAAACCAGTTAATACGAGATATGGAGGCAGAATAATATTTGTGGACGATTGTATTGATTTAAATCATT
ACATATCATTTTTAGAAAGCACACCGAAGCAAGTTGTTTATGAAACGGTATAG

Upstream 100 bases:

>100_bases
ACTAAGCCAATGTTAAGAATATCATTGTCGTATTTTCATACTGAACAAGATATAGATAGGTTGTTTGAAATTTTGCATCA
AGAAGATTGAGGTGATCGTC

Downstream 100 bases:

>100_bases
GGGTTTTAGTATGACATCAAAAGATATTACTCAAATTAGTGTCATTGCTGCGATTTTAACCATTTTGGCAGTTTTGAAAA
TACCGTCCATTATACCAGGA

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLT
QECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPY
VKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV

Sequences:

>Translated_230_residues
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLT
QECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPY
VKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
>Mature_230_residues
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLT
QECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPY
VKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV

Specific function: Transforms pimelate into pimeloyl-CoA

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOW_STAA1 (A7X666)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442997.1
- STRING:   A7X666
- EnsemblBacteria:   EBSTAT00000003951
- GeneID:   5561176
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2407
- eggNOG:   COG1424
- GeneTree:   EBGT00050000025018
- HOGENOM:   HBG507782
- OMA:   TVDAIAI
- ProtClustDB:   PRK01322
- BioCyc:   SAUR418127:SAHV_2407-MONOMER
- HAMAP:   MF_00668
- InterPro:   IPR005499
- ProDom:   PD017229

Pfam domain/function: PF03744 BioW

EC number: =6.2.1.14

Molecular weight: Translated: 26092; Mature: 26092

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPI
CEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHH
QQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSF
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCCCEEHHHHHHHHHCCCHHHHH
GQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAA
HHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHH
AKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
HHHCHHHEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHEECC
>Mature Secondary Structure
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPI
CEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHH
QQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSF
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCHHHCCCCEEHHHHHHHHHCCCHHHHH
GQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAA
HHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHH
AKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
HHHCHHHEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA