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The map label for this gene is gpmA

Identifier: 57650960

GI number: 57650960

Start: 2474088

End: 2474774

Strand: Reverse

Name: gpmA

Synonym: SACOL2415

Alternate gene names: 57650960

Gene position: 2474774-2474088 (Counterclockwise)

Preceding gene: 57650961

Following gene: 57650958

Centisome position: 88.09

GC content: 33.62

Gene sequence:

>687_bases
ATGCCAAAATTAATTTTATGTCGTCATGGACAAAGCGAGTGGAATGCTAAAAACTTATTTACTGGATGGGAAGATGTTAA
TTTATCTGAACAAGGTATTAATGAAGCGACTAGAGCAGGTGAAAAAGTAAGAGAAAATAACATTGCCATCGATGTAGCTT
TTACATCGTTATTAACACGTGCTTTAGATACAACGCATTATATTTTAACTGAATCTAAACAACAATGGATTCCTGTATAT
AAAAGCTGGCGTTTAAATGAACGCCACTATGGTGGATTGCAAGGCTTAAATAAAGATGATGCTAGAAAAGAATTTGGAGA
AGAACAAGTACATATTTGGCGTCGTTCTTATGATGTGAAACCACCTGCTGAAACCGAAGAACAACGTGAAGCTTACTTAG
CTGATCGTCGATATAATCATTTAGATAAACGTATGATGCCTTATTCTGAAAGTCTGAAAGATACTTTAGTTCGAGTGATA
CCATTTTGGACAGATCATATTTCACAATATTTGCTAGATGGTCAAACGGTATTAGTTTCTGCACACGGAAATTCAATTCG
CGCATTGATTAAATATCTTGAAGATGTGTCAGATGAAGATATCATTAATTATGAAATTAAAACAGGTGCACCGCTTGTTT
ATGAATTAACGGATGATTTAGAAGTTATAGATAAATACTACTTATAA

Upstream 100 bases:

>100_bases
GAATTTTAAAATATATTGAAAAGAAAATTACTAAGATTAAATCATCTTAAAATATCCCTGAAATAACGTCCTAAAGATTA
AAGGAAAGAGGTTATAAGTT

Downstream 100 bases:

>100_bases
AAAAAGAGCTGCATGTACACAAGGAGTGAGTGTATATGCAGCTCTTAAATATGTGAAGTAATGTAAGGAAATAGTTAAGT
ATAGAGTTTATATTAACGAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVY
KSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVI
PFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL

Sequences:

>Translated_228_residues
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVY
KSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVI
PFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>Mature_227_residues
PKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYK
SWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIP
FWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=221, Percent_Identity=45.2488687782805, Blast_Score=221, Evalue=5e-58,
Organism=Homo sapiens, GI4502445, Length=228, Percent_Identity=46.4912280701754, Blast_Score=218, Evalue=2e-57,
Organism=Homo sapiens, GI40353764, Length=228, Percent_Identity=46.4912280701754, Blast_Score=218, Evalue=2e-57,
Organism=Homo sapiens, GI4505753, Length=223, Percent_Identity=46.6367713004484, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI71274132, Length=223, Percent_Identity=43.9461883408072, Blast_Score=195, Evalue=3e-50,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=47.8260869565217, Blast_Score=151, Evalue=6e-37,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=47.787610619469, Blast_Score=233, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=50.2183406113537, Blast_Score=240, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324516, Length=275, Percent_Identity=32.3636363636364, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320183, Length=281, Percent_Identity=32.0284697508897, Blast_Score=133, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324857, Length=101, Percent_Identity=33.6633663366337, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646216, Length=225, Percent_Identity=48.8888888888889, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=45.5357142857143, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=45.5357142857143, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=45.5357142857143, Blast_Score=201, Evalue=3e-52,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=36.405529953917, Blast_Score=153, Evalue=9e-38,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=36.405529953917, Blast_Score=153, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=36.405529953917, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_STAA1 (A7X656)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442990.1
- ProteinModelPortal:   A7X656
- SMR:   A7X656
- STRING:   A7X656
- EnsemblBacteria:   EBSTAT00000003591
- GeneID:   5559468
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2400
- eggNOG:   COG0588
- GeneTree:   EBGT00050000023828
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14119
- BioCyc:   SAUR418127:SAHV_2400-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 26680; Mature: 26549

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTR
CCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCEEEEHHHHHHHHH
ALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVK
HHHHHHEEEECCCCHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
PPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVS
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
ECCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHCC
>Mature Secondary Structure 
PKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTR
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCEEEEHHHHHHHHH
ALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVK
HHHHHHEEEECCCCHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
PPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVS
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
ECCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA