Click here to switch to the map view.

The map label for this gene is tcyB [H]

Identifier: 57650956

GI number: 57650956

Start: 2470616

End: 2471344

Strand: Reverse

Name: tcyB [H]

Synonym: SACOL2411

Alternate gene names: 57650956

Gene position: 2471344-2470616 (Counterclockwise)

Preceding gene: 57650957

Following gene: 57650955

Centisome position: 87.97

GC content: 33.61

Gene sequence:

>729_bases
TTGGTCAAGATGTTTCTAAATCTAAATAGTGAACAACAACATGCGCTAGATGCTGCAAAACAAGCTTTCGGACCTATGCT
AGAAGGTTTGGTCAAATATTCAATTCCTATTACATTAGTTACATTTGTTTTAGGATTGATTATTGCATTATTTACAGCAT
TAATGCGAATTTCAACGAGTAAAATTTTAAGAAGTATTTCACGTGTCTATGTATCTATTATTCGAGGAACACCAATGATA
GTACAACTATTTATCATATTTTATGGTATTCCAGAATTAGGTAGATTATTAACAAATGACGCTGACAACCAATGGACATT
GGCACCTGTAGTGGCTGCTATTATTGGTTTATCATTAAATGTAGGTGCGTATGCTTCGGAAATTATTCGTGGCGGTATTA
TTTCTATACCGAAAGGACAAACAGAAGCTGCATATTCCATCGGTATGACGTATGGTCAAACGATACAACGTATCATTTTA
CCGCAGGCAATTCGAGTGTCGATTCCTGCACTAGGTAATACATTTTTAAGTTTAATCAAAGATACATCATTATTAGGATT
TATTTTAGTGGCTGAAATGTTTAGAAAAGCTCAAGAAGTTGCGTCTACAACATATGAATATTTAACAATTTATGTGTTAG
TTGCGCTAATGTACTGGGTGGTATGCTTTATTATTTCAATTATCCAAGGTATCTATGAATCTTATATTGAAAGAGGGTAT
CGCTCATGA

Upstream 100 bases:

>100_bases
TTTTCTAAAAAAGCAGATGATGAAACAGTTCAAAAATTCAATGATGGCTTGAAAAAAATCGAGGAAAACGGTGAATTAGC
TAAAATAGGTAAGAAATGGT

Downstream 100 bases:

>100_bases
TTCAATTGACCAATATCCATAAATCATTTAATGATGTTGAAGTCATCAAAGGTATTGATTTATCTGTTGAACAAGGTGAG
GTTGTAACCTTAATCGGTCG

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMI
VQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIIL
PQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGY
RS

Sequences:

>Translated_242_residues
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMI
VQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIIL
PQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGY
RS
>Mature_242_residues
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMI
VQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIIL
PQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGY
RS

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=218, Percent_Identity=44.4954128440367, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=34.8039215686275, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082239, Length=194, Percent_Identity=34.5360824742268, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=32.1608040201005, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=31.7757009345794, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788645, Length=187, Percent_Identity=28.8770053475936, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787087, Length=206, Percent_Identity=27.6699029126214, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787086, Length=182, Percent_Identity=31.8681318681319, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786874, Length=184, Percent_Identity=25.5434782608696, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI48994930, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26801; Mature: 26801

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTS
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCC
VGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIK
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RS
CC
>Mature Secondary Structure
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTS
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCC
VGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIK
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]