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The map label for this gene is nreB [H]

Identifier: 57650935

GI number: 57650935

Start: 2448908

End: 2449942

Strand: Reverse

Name: nreB [H]

Synonym: SACOL2390

Alternate gene names: 57650935

Gene position: 2449942-2448908 (Counterclockwise)

Preceding gene: 57650936

Following gene: 57650934

Centisome position: 87.2

GC content: 33.62

Gene sequence:

>1035_bases
ATGATTAATGAGGACAGTATACAGTTAGATACTTTATTGAAAAAATATTATGAGCATTCAATCGAAAAGATAGTTTTTGC
TGATGATAACGGTAAAATTATTGCAATGAATGATGCTGCTAAAGATATATTATCTGAAGAAGATAATTACAGTGCTGTGG
CGAATGCGATTTGTCACAGATGTGAAGGGTATACAAATGCCTATGATGTACAATCATGTAAAGACTGTTTCTTAGAATCG
ATGCAAGTACAAGCTACGAATTTCCAAGTATTTATGAAGACGAAAGATCAAAAAGTGATGCCATTTACAGCAACATATCA
GTTGATTGATCAAGACAGGGGAATTCATGCATTTACGCTTCAAAATGTTTCATCACAAATTGAACAGCAAGAGAAATTGC
ATCAACAACGTATGATGCGTAAAACAATCTCAGCCCAAGAAAATGAAAGAAAGCGAATTTCTAGAGAGTTACATGATAGT
GTGATTCAAGAAATGCTCAATGTAGATGTTCAATTGAGATTATTAAAATATCAAGAAGATACAACTAAGCTTTTGGAAGA
CGCAGAAAATATTGAATATATTGTCGCTAAATTAATTGATGATATACGTAATATGTCGGTTGAATTAAGACCCGCTTCTT
TGGATGATCTAGGCCTTGAAGCAGCTTTTAAATCATATTTTAAACAGTTTGAAGAAAATTATGGAATAAAAATCATATAT
ACATCAAATATTAAAAATACTCGCTTTGATAGTGATATTGAAACGGTTGTTTATCGAGTAGTGCAAGAAGCTATTTTAAA
TGCGTTGAAATACGCTGATGTAAATGAAATAAATGTAGGTATCCGTCAAACTGGGCGCCATTTGGTAGCAGAAGTGATAG
ATGCGGGAAATGGTTTTGATCCAAGTTCTAAGCCTAAAGGTTCTGGACTCGGTTTATATGGAATGAATGAGCGAGCTGAG
TTAGTCAGCGGTAGCGTCAATATTGAAACGAAAATTGGTGAGGGTACCAATGTTACATTGAACATTCCAATTTGA

Upstream 100 bases:

>100_bases
ATGGTCGTCCTTTACCAAAAATATTTGATAATGATGATATTCAACGTAAGTTTGGTATTTTCAATGATGATAAATAATGA
GATGAATTAGGGTGTAAGTC

Downstream 100 bases:

>100_bases
AACATACATTGGGGGAATAAAATTGAAAATAGTCATTGCCGATGATCACGCTGTTGTCCGTACGGGGTTCTCTATGATTT
TAAATTATCAAAATGATATG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLES
MQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDS
VIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIY
TSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAE
LVSGSVNIETKIGEGTNVTLNIPI

Sequences:

>Translated_344_residues
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLES
MQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDS
VIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIY
TSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAE
LVSGSVNIETKIGEGTNVTLNIPI
>Mature_344_residues
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLES
MQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDS
VIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIY
TSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAE
LVSGSVNIETKIGEGTNVTLNIPI

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=217, Percent_Identity=28.110599078341, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788812, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39121; Mature: 39121

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50109 HIS_KIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHR
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHH
CEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTL
HCCCCCCCCHHHHHHHHHHHHHEEECCEEEEEECCCCEECCHHHHHHHHHCCCCEEEEEH
QNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQED
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
TTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
TSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFD
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCC
PSSKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI
CCCCCCCCCEEEECCCCHHHHHCCCEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHR
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHH
CEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTL
HCCCCCCCCHHHHHHHHHHHHHEEECCEEEEEECCCCEECCHHHHHHHHHCCCCEEEEEH
QNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQED
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
TTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
TSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFD
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHCCCCCC
PSSKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI
CCCCCCCCCEEEECCCCHHHHHCCCEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA