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The map label for this gene is gltS [H]

Identifier: 57650888

GI number: 57650888

Start: 2399779

End: 2400987

Strand: Direct

Name: gltS [H]

Synonym: SACOL2340

Alternate gene names: 57650888

Gene position: 2399779-2400987 (Clockwise)

Preceding gene: 57650887

Following gene: 57650891

Centisome position: 85.42

GC content: 32.59

Gene sequence:

>1209_bases
ATGATAGAACTTAATGCAATTACAACATTATGTTTAGCTTGTATCCTTTATTTACTTGGTAAGGCTATCGTTAATCACGT
TAATTTTTTAAAACGTATTTGTATACCAGCACCAGTGATTGGCGGCTTAATCTTTGCTATTTTAGTTGCGGCTTTGGATT
CATTTGGCATGGTTAAGATTAAATTAGATGCTTCATTCATTCAAGATTTCTTCATGTTAGCATTCTTTACGACAATCGGT
CTTGGTGCATCATTGAAATTATTTAAATTAGGTGGCAAAGTCTTGCTATTATACTTTATGTTTTGTGCTATCATTTCAGT
CATTCAAAACATAGTTGGTGTATCACTAGCAAAAGTATTAAATATTAAACCTTTGTTAGGATTAACAGCAGGTTCCATGT
CTATGGAAGGCGGTCATGGTAATGCTGCTGCTTATGGTAAGACAATTCAAGATTTAGGTATTGATTCGGCACTGACAGCG
GCTCTTGCAGCTGCAACTTTAGGTCTTGTATTTGGAGGGCTTATCGGTGGTCCAGTTGTAAAATTTTTAATCAAACGTTA
TAACTTAAAGCCTCAACATAGTGACGATACATTTAAAGATTATAGCCAAGTAGCATATAACGAACATTTACATAGTAAAT
TTAATGCCACTGAAGTATTCTTCATTCAATTTACAATCGTTGTATTCTGTATGGCAGTTGGAAGTTATTTCAGTCATTTG
TTTACAGCTCAAACAGGGATTAATGTTCCAATTTACGTTGGCTCATTATTTGTAGCTGTTATTGTCCGAAATATCTCTGA
AAGTTTTAATTTTAATATTGTAGATTTAAAAATTACTAATCAAATTGGCGATGTCGCATTAGGTATTTTCTTATCTCTTG
CGCTAATGAGCATTCAATTAATCGAAATTTATAAACTTGCTATACCTCTTATTATTATCGTTTTAGTTCAAGTTGTCGTT
ATGATTTTATTTGCTGTTTTAATTTTATTTAGAGGTTTAGGAAAAGATTATGATGCTGCAGTAATGGTAGGTGGTTTTAT
CGGTCATGGGCTTGGTGCAACGCCAAATGCCATGGCAAATTTAGATGTTATTACTAAAAAATATGGAAACTCACCTAAAG
CATATTTAGTTGTACCTATTGTTGGTGCATTCTTAATCGATTTAATTGGTGTTATAGTCATTATGGGATTCATACAATGG
TTTAGTTAA

Upstream 100 bases:

>100_bases
ATTGATTTGTTGCATGTATAATGTTAAAAGCGCCCTTTTATAACGCTTACATATAAAAGCTTATTTAGGGAGAGGGATAT
TCAACAAGGGGGATTTGAAA

Downstream 100 bases:

>100_bases
ACACCAAACTCATAAATAAAAGAGGAGGCCTTCGCCTCCTCTTTTATTTATCCTCGATGTATATTCAAGTTACGTTGTTC
TATCCATGACAATATTTCCG

Product: sodium:glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MIELNAITTLCLACILYLLGKAIVNHVNFLKRICIPAPVIGGLIFAILVAALDSFGMVKIKLDASFIQDFFMLAFFTTIG
LGASLKLFKLGGKVLLLYFMFCAIISVIQNIVGVSLAKVLNIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTA
ALAAATLGLVFGGLIGGPVVKFLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATEVFFIQFTIVVFCMAVGSYFSHL
FTAQTGINVPIYVGSLFVAVIVRNISESFNFNIVDLKITNQIGDVALGIFLSLALMSIQLIEIYKLAIPLIIIVLVQVVV
MILFAVLILFRGLGKDYDAAVMVGGFIGHGLGATPNAMANLDVITKKYGNSPKAYLVVPIVGAFLIDLIGVIVIMGFIQW
FS

Sequences:

>Translated_402_residues
MIELNAITTLCLACILYLLGKAIVNHVNFLKRICIPAPVIGGLIFAILVAALDSFGMVKIKLDASFIQDFFMLAFFTTIG
LGASLKLFKLGGKVLLLYFMFCAIISVIQNIVGVSLAKVLNIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTA
ALAAATLGLVFGGLIGGPVVKFLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATEVFFIQFTIVVFCMAVGSYFSHL
FTAQTGINVPIYVGSLFVAVIVRNISESFNFNIVDLKITNQIGDVALGIFLSLALMSIQLIEIYKLAIPLIIIVLVQVVV
MILFAVLILFRGLGKDYDAAVMVGGFIGHGLGATPNAMANLDVITKKYGNSPKAYLVVPIVGAFLIDLIGVIVIMGFIQW
FS
>Mature_402_residues
MIELNAITTLCLACILYLLGKAIVNHVNFLKRICIPAPVIGGLIFAILVAALDSFGMVKIKLDASFIQDFFMLAFFTTIG
LGASLKLFKLGGKVLLLYFMFCAIISVIQNIVGVSLAKVLNIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTA
ALAAATLGLVFGGLIGGPVVKFLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATEVFFIQFTIVVFCMAVGSYFSHL
FTAQTGINVPIYVGSLFVAVIVRNISESFNFNIVDLKITNQIGDVALGIFLSLALMSIQLIEIYKLAIPLIIIVLVQVVV
MILFAVLILFRGLGKDYDAAVMVGGFIGHGLGATPNAMANLDVITKKYGNSPKAYLVVPIVGAFLIDLIGVIVIMGFIQW
FS

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=376, Percent_Identity=38.8297872340425, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43265; Mature: 43265

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIELNAITTLCLACILYLLGKAIVNHVNFLKRICIPAPVIGGLIFAILVAALDSFGMVKI
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEE
KLDASFIQDFFMLAFFTTIGLGASLKLFKLGGKVLLLYFMFCAIISVIQNIVGVSLAKVL
EECHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTAALAAATLGLVFGGLIGGPVV
CCCHHHCCCCCCCCCCCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KFLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATEVFFIQFTIVVFCMAVGSYFSHL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FTAQTGINVPIYVGSLFVAVIVRNISESFNFNIVDLKITNQIGDVALGIFLSLALMSIQL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHH
IEIYKLAIPLIIIVLVQVVVMILFAVLILFRGLGKDYDAAVMVGGFIGHGLGATPNAMAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHH
LDVITKKYGNSPKAYLVVPIVGAFLIDLIGVIVIMGFIQWFS
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]