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The map label for this gene is yybE [H]

Identifier: 57650874

GI number: 57650874

Start: 2387560

End: 2388444

Strand: Direct

Name: yybE [H]

Synonym: SACOL2325

Alternate gene names: 57650874

Gene position: 2387560-2388444 (Clockwise)

Preceding gene: 57650866

Following gene: 57650875

Centisome position: 84.98

GC content: 31.53

Gene sequence:

>885_bases
ATGAAAATTATTCAGTTAGAATACTTCTTGGCTATCGTGAAATATAATAGTTTTACTAAAGCTGCACAATTTTTACATAT
TAGCCAGCCATCTTTAACTGCTACGATTAAAAAAATGGAAGCAGATTTAGGTTATGACTTATTTACACGTTCAACAAAAG
ACATCAAGATTACCGAAAAAGGAATACAGTTTTATCGTTATGCGAGCGAATTAGTTCAACAATATCGATCCACGATGGAA
AAAATGTATGATTTAAGCGTTACATCAGAACCAAGGATAAAAATTGGGACTCTTGAATCTACGAATCAATGGATTGCGAA
TTTAATTCGAAAGCACCATTCCGACTACCCTGAACAGCAATATCGTTTATATGAAATACATGATAAACATCAATCTATAG
AGCAATTACTGAATTTTAATATTCATTTAGCTATAACAAATGAAAAAATAACCCACGAAGATATAAGATCCATTCCTTTA
TATGAGGAATCTTACATTTTATTAGCACCCAAGGAAACATTTAAAAATCAAAATTGGGTAGATGTTGAAAATTTGCCACT
CATATTACCAAACAAAAATTCTCAAGTGCGCAAACACTTAGATGACTATTTTAATAGAAGAAATATTCGTCCAAATGTCG
TTGTAGAAACAGATCGATTCGAATCAGCAGTTGGATTTGTTCATCTCGGCTTAGGTTACGCTATCATTCCGAGATTTTAT
TACCAATCATTTCACACGTCTAATTTAGAATATAAAAAAATTCGTCCAAACTTAGGCCGAAAAATTTATATCAATTACCA
TAAAAAACGCAAACACTCCGAACAAGTACATACATTCGTACAACAATGCCAAGATTATTTATATGGACTTTTAGAGGCTC
TTTAA

Upstream 100 bases:

>100_bases
TTATCTTCAATATTCATTATAGTATGTTAAAATATAGCCAACAAATATAAATAAACTAATTATCCATAGCTTGAATCTAT
AAATAAAAGGAGCAAAACAC

Downstream 100 bases:

>100_bases
CTTAAGTTATTAGAGCCTCTTATGCAGTTGCTCAGTCAACTGTATACCTTTTGCCTTTAACTTAAGTTATTAGAGCCTCT
TATGCAGTTGCTCAGTCAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTME
KMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPL
YEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFY
YQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL

Sequences:

>Translated_294_residues
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTME
KMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPL
YEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFY
YQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL
>Mature_294_residues
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTME
KMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPL
YEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFY
YQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=25.8771929824561, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787806, Length=247, Percent_Identity=25.5060728744939, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=23.2931726907631, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=21.2837837837838, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI145693105, Length=238, Percent_Identity=24.3697478991597, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787530, Length=244, Percent_Identity=24.1803278688525, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790399, Length=188, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=23.7154150197628, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=285, Percent_Identity=23.1578947368421, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=126, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=243, Percent_Identity=20.9876543209877, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786508, Length=90, Percent_Identity=35.5555555555556, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=23.4177215189873, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35019; Mature: 35019

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEK
CEEEEHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCCCEEEEHH
GIQFYRYASELVQQYRSTMEKMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHH
YRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPLYEESYILLAPKETFKNQNWV
HEEHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEECHHHHCCCCCE
DVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFY
ECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
YQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL
HHHHCCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEK
CEEEEHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCCCEEEEHH
GIQFYRYASELVQQYRSTMEKMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHH
YRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPLYEESYILLAPKETFKNQNWV
HEEHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEECHHHHCCCCCE
DVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFY
ECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
YQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL
HHHHCCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]