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The map label for this gene is gapA2

Identifier: 57650558

GI number: 57650558

Start: 1765067

End: 1766092

Strand: Reverse

Name: gapA2

Synonym: SACOL1734

Alternate gene names: 57650558

Gene position: 1766092-1765067 (Counterclockwise)

Preceding gene: 57650559

Following gene: 57650557

Centisome position: 62.86

GC content: 32.85

Gene sequence:

>1026_bases
ATGTCAACGAATATTGCAATTAATGGTATGGGTAGAATTGGAAGAATGGTATTACGTATTGCATTACAAAATAAAAATTT
AAATGTAGTAGCGATAAATGCTAGTTATCCACCCGAAACAATTGCACATTTAATCAATTACGATACGACACATGGAAAAT
ATAATCTAAAAGTTGAACCGATTGAAAATGGATTGCAAGTTGGAGATCATAAAATTAAATTGGTTGCTGATCGCAATCCT
GAAAACTTGCCATGGAAAGAATTAGATATCGATATTGCTATAGATGCAACTGGTAAATTTAATCATGGTGATAAAGCCAT
CGCACATATTAAAGCAGGTGCCAAAAAAGTTTTGTTAACTGGTCCTTCAAAAGGTGGACATGTTCAAATGGTAGTTAAAG
GCGTAAATGATAACCAATTAGATATAGAAGCATTTGACATTTTTAGTAATGCTTCATGTACTACTAATTGCATTGGTCCA
GTTGCAAAAGTTTTAAATAATCAGTTTGGAATAGTTAATGGTTTAATGACTACTGTTCACGCTATTACAAATGACCAAAA
AAATATTGATAATCCACATAAAGATTTAAGACGTGCACGTTCATGTAATGAAAGCATTATTCCTACTTCTACTGGTGCGG
CGAAAGCTTTAAAAGAAGTATTACCAGAATTAGAAGGTAAATTACACGGCATGGCATTACGTGTACCAACAAAGAATGTA
TCGCTCGTTGATTTAGTTGTTGATTTAGAAAAAGAAGTAACTGCAGAAGAAGTAAACCAAGCTTTTGAAAATGCAGGTTT
AGAAGGTATCATAGAAGTCGAACATCAACCACTAGTGTCTGTTGATTTTAATACTAATCCAAATTCAGCTATTATTGATG
CAAAATCAACAATGGTCATGTCAGGGAATAAAGTAAAAGTTATTGCTTGGTATGATAATGAATGGGGTTATTCAAATAGA
GTTGTAGATGTTGCTGAGCAAATTGGAGCACTTTTGACATCAAAAGAAACTGTAAGTGCAAGTTAA

Upstream 100 bases:

>100_bases
AAAAAGATAAATAAATCAACGGAAAACGCTTTCAAATTTCATATAATATGCTATACTAATTCCATAAAGTATAACACATA
AAGATCAAGGGGTGCTTTTA

Downstream 100 bases:

>100_bases
TACAATTAATTTATAGCCTAACTCTGACTTCGGAGTTAGGTTTTTTATTTTTAATACAATAATATTGTCATGCAAATTAC
TTAATAAGTAACGATATAAT

Product: glyceraldehyde 3-phosphate dehydrogenase 2

Products: NA

Alternate protein names: GAPDH 2

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNP
ENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGP
VAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNV
SLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNR
VVDVAEQIGALLTSKETVSAS

Sequences:

>Translated_341_residues
MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNP
ENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGP
VAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNV
SLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNR
VVDVAEQIGALLTSKETVSAS
>Mature_340_residues
STNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNPE
NLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGPV
AKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNVS
LVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNRV
VDVAEQIGALLTSKETVSAS

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=43.8650306748466, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI7669492, Length=337, Percent_Identity=43.026706231454, Blast_Score=273, Evalue=2e-73,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=47.8915662650602, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=43.161094224924, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=44.1791044776119, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=43.8805970149254, Blast_Score=284, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=44.4776119402985, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=44.4776119402985, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=50.4559270516717, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=48.7878787878788, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=48.4848484848485, Blast_Score=307, Evalue=2e-84,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=44.7447447447448, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=44.7447447447448, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=45.5927051671732, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=45.5927051671732, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=42.9003021148036, Blast_Score=262, Evalue=2e-70,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): G3P2_STAAC (Q5HF86)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186571.1
- ProteinModelPortal:   Q5HF86
- SMR:   Q5HF86
- STRING:   Q5HF86
- EnsemblBacteria:   EBSTAT00000010237
- GeneID:   3238151
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1734
- TIGR:   SACOL1734
- eggNOG:   COG0057
- GeneTree:   EBGT00050000024492
- HOGENOM:   HBG571736
- OMA:   DFNTNPH
- ProtClustDB:   CLSK885496
- BioCyc:   SAUR93062:SACOL1734-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR10836
- PIRSF:   PIRSF000149
- PRINTS:   PR00078
- SMART:   SM00846
- TIGRFAMs:   TIGR01534

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.12

Molecular weight: Translated: 36980; Mature: 36848

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 153-153 BINDING 78-78 BINDING 183-183 BINDING 198-198 BINDING 234-234 BINDING 313-313

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEP
CCCCEEEECCHHHHHHHEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEEEE
IENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLT
CCCCCEECCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCCCHHHEEECCCCEEEEEE
GPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGPVAKVLNNQFGIVNGLMTTVH
CCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
AITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNV
HHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVM
EEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCEEEECCCEEEE
SGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTSKETVSAS
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHLINYDTTHGKYNLKVEP
CCCEEEECCHHHHHHHEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEEEE
IENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNHGDKAIAHIKAGAKKVLLT
CCCCCEECCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCCCHHHEEECCCCEEEEEE
GPSKGGHVQMVVKGVNDNQLDIEAFDIFSNASCTTNCIGPVAKVLNNQFGIVNGLMTTVH
CCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
AITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPELEGKLHGMALRVPTKNV
HHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQPLVSVDFNTNPNSAIIDAKSTMVM
EEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCEEEECCCEEEE
SGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTSKETVSAS
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA