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The map label for this gene is dtd

Identifier: 57650514

GI number: 57650514

Start: 1717645

End: 1718097

Strand: Reverse

Name: dtd

Synonym: SACOL1688

Alternate gene names: 57650514

Gene position: 1718097-1717645 (Counterclockwise)

Preceding gene: 57650515

Following gene: 57650513

Centisome position: 61.15

GC content: 32.01

Gene sequence:

>453_bases
ATGAAAGTAGTTGTACAAAGAGTTAAAGAAGCATCGGTGACGAATGATACATTAAATAATCAAATCAAAAAAGGATATTG
TTTATTAGTCGGTATCGGTCAGAACTCTACAGAGCAAGATGCAGATGTAATTGCAAAGAAAATTGCTAATGCAAGATTAT
TTGAAGATGACAATAATAAATTAAACTTTAATATCCAACAAATGAATGGTGAAATACTATCAGTTTCACAATTTACTCTC
TATGCAGATGTAAAAAAAGGTAACCGTCCAGGTTTCTCAAATTCTAAAAATCCTGATCAAGCGGTAAAAATTTATGAGTA
TTTTAATGATGCGCTACGAGCGTATGGTCTTACTGTGAAAACAGGTGAATTTGGAACACACATGAATGTTAGCATAAATA
ATGATGGTCCAGTCACTATTATTTATGAAAGTCAGGACGGCAAAATTCAATGA

Upstream 100 bases:

>100_bases
TGGTGAAAAACGTGAATGATGTTTATCGTGTGGTAGAAAAGATCAAACAACTTGGTGATGTTTATACAGTAACAAGAGTT
TGGAACTAGAGGTGCAAAAT

Downstream 100 bases:

>100_bases
AAAAAATAGAGGCATGGTTATCTAAAAAGGGTCTTAAAAATAAACGTACTCTAATAGTAGTGATTGCCTTTGTCTTATTT
ATCATCTTTTTATTTTTATT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTL
YADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ

Sequences:

>Translated_150_residues
MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTL
YADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
>Mature_150_residues
MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTL
YADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=42.5675675675676, Blast_Score=100, Evalue=8e-22,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=39.5833333333333, Blast_Score=120, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=40.6666666666667, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=46.6216216216216, Blast_Score=120, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=43.046357615894, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_STAA1 (A7X347)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442210.1
- ProteinModelPortal:   A7X347
- SMR:   A7X347
- STRING:   A7X347
- EnsemblBacteria:   EBSTAT00000003869
- GeneID:   5560243
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1620
- eggNOG:   COG1490
- GeneTree:   EBGT00050000024776
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   SAUR418127:SAHV_1620-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16697; Mature: 16697

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: ACT_SITE 79-79

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNK
CHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCE
LNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVK
EEEEEEECCCEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEE
TGEFGTHMNVSINNDGPVTIIYESQDGKIQ
CCCCCCEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNK
CHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCE
LNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVK
EEEEEEECCCEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEE
TGEFGTHMNVSINNDGPVTIIYESQDGKIQ
CCCCCCEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA