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The map label for this gene is xseA

Identifier: 57650480

GI number: 57650480

Start: 1603767

End: 1605104

Strand: Reverse

Name: xseA

Synonym: SACOL1568

Alternate gene names: 57650480

Gene position: 1605104-1603767 (Counterclockwise)

Preceding gene: 57650481

Following gene: 57650479

Centisome position: 57.13

GC content: 31.24

Gene sequence:

>1338_bases
ATGTCAGATTATTTAAGTGTTTCAGCTTTAACGAAATATATTAAATATAAATTTGATCAAGATCCACATCTCCAATCTGT
ATTGATTAAAGGTGAGCTTTCAAATTTCAAAAAGCATTCAAGTGGTCATTTATACTTTAATGTGAAAGATAAAGAAAGCG
TTATAAGTGCCATGATGTTCAAAGGTAGTGCTTCTAAATTAAACTTCGAACCTAAAGAAGGAGATGAAGTCTTATTAGAA
GCACGTGTTTCTGTTTTTGAACGTCGTGGAAACTATCAAATTTATGTAAATAAAATGCAATTAGATGGTATAGGGAACTT
ATATCAAAAATTAGAAGCATTAAAGAAAAAATTAACTGAAGAAGGTTGTTTTGATAAAGCGAATAAGAAATCAATACCTA
AGTTTCCTAAAAAAATTGCAGTTTTAACAGCGAGTACAGGTGCCGCAATTCGAGATATCCATTCAACGATAAATAGTCGT
TTTCCATTAGCTGAACAAATACAAATTAGTACTTTGGTTCAAGGTGAAAAAGCAAAAGACGACATTATTGAAAAAATTGA
ATATGCAGATAGTTTAGGTGTAGATACCATTATTGTAGGTCGAGGCGGTGGATCCATAGAAGATTTATGGAATTTCAACG
AAGAAGCTGTCGTCCGTGCAATATATAATTGTAAGACACCGATTATATCAGCAGTTGGTCATGAAACAGACTTTACATTA
AGTGATTTTGCTGCAGACATCAGAGCTGCGACTCCAACTCAAGCTGCTGTTATTGCAACACCAGACCAATATGAATTGCT
GCAACAAATACAGCAATATCAGTTTACATTGACTCGTTTCATCAAGAAACATTTAGAACAACAACGTAAACATGTTGAAC
ATTTGTCATCGTATTACAAGTTTAAACAACCAACTTTATTGTATGATCAACAGATACAACGTCGAGATGATTTAGAAAAG
AGACTGAAACAACAAATTCAGGCAACTTTTGAACAACAGAGACATCGATTAATGCTGTTGCAACAACGTTATAATTTAAA
AGCATTACTAAGTAGTGTTAATCAAGAACAACAAAATAATCTTCAATTGACAAACCAACTTGTTAAATTATTGAATTCTA
AGATATTAAGTTATAAAAATGATTTGAAAAATAAAGTAGAAAACTTAAACAATTTAAGTCCAACTAATACAATGTTGCGT
GGATATGCAATTGTTAATAAAAAAGACGAAGTCATTACGAGTACTAAAGATTTAACAGAAAATGATCAATTGACGTTAAC
AATGAAAGATGGCTTAGTAGATGCAAAAGTTACGAAAGTAAGGTGTAATAATGACTAA

Upstream 100 bases:

>100_bases
GAAGCAGTTGAATTAACAAAACAATTCAGTGATGATGATCATTATAAATTTATAAATGGTGTATTGAGTAATATAAAAAA
ATAAAATTGAGTGATGTTAT

Downstream 100 bases:

>100_bases
AGAAACGCAAAGTTTTGAAGAAATGATGCAAGAATTAGAGCAAATTGTTCAAAAATTAGATAATGAAACAGTATCTTTAG
AGGAATCATTAGATTTATAT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLE
ARVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSR
FPLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTL
SDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEK
RLKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLR
GYAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND

Sequences:

>Translated_445_residues
MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLE
ARVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSR
FPLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTL
SDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEK
RLKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLR
GYAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND
>Mature_444_residues
SDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLEA
RVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSRF
PLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTLS
DFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEKR
LKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLRG
YAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=438, Percent_Identity=34.4748858447489, Blast_Score=271, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_STAA1 (A7X2Q2)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442101.1
- STRING:   A7X2Q2
- EnsemblBacteria:   EBSTAT00000005188
- GeneID:   5560031
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1511
- eggNOG:   COG1570
- GeneTree:   EBGT00050000024703
- HOGENOM:   HBG634411
- OMA:   EQRASIG
- ProtClustDB:   PRK00286
- BioCyc:   SAUR418127:SAHV_1511-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 50895; Mature: 50764

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMF
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
KGSASKLNFEPKEGDEVLLEARVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
EGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSRFPLAEQIQISTLVQGEKAKD
HCCCCCCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
DIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTL
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCCH
SDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYK
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKQPTLLYDQQIQRRDDLEKRLKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
LQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLRGYAIVNKKDEVITSTKDLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCHHHHHCCCCCCC
NDQLTLTMKDGLVDAKVTKVRCNND
CCCEEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHLYFNVKDKESVISAMMF
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
KGSASKLNFEPKEGDEVLLEARVSVFERRGNYQIYVNKMQLDGIGNLYQKLEALKKKLTE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
EGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSRFPLAEQIQISTLVQGEKAKD
HCCCCCCCCCCCCCCCHHEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
DIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVVRAIYNCKTPIISAVGHETDFTL
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCCH
SDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFTLTRFIKKHLEQQRKHVEHLSSYYK
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKQPTLLYDQQIQRRDDLEKRLKQQIQATFEQQRHRLMLLQQRYNLKALLSSVNQEQQNN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
LQLTNQLVKLLNSKILSYKNDLKNKVENLNNLSPTNTMLRGYAIVNKKDEVITSTKDLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCHHHHHCCCCCCC
NDQLTLTMKDGLVDAKVTKVRCNND
CCCEEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA