Click here to switch to the map view.

The map label for this gene is ald1

Identifier: 57650394

GI number: 57650394

Start: 1515797

End: 1516915

Strand: Reverse

Name: ald1

Synonym: SACOL1478

Alternate gene names: 57650394

Gene position: 1516915-1515797 (Counterclockwise)

Preceding gene: 57650395

Following gene: 57650393

Centisome position: 53.99

GC content: 35.39

Gene sequence:

>1119_bases
ATGTTAGTTGCAGTAGTCAAAGAATTAAAACAAGGTGAAGGACGTGTAGCTTGCACACCCGAAAATGTGCGTAAGTTAAC
GGATGCAGGACATAAAGTAATTGTTGAAAAAAATGCTGGCATTGGTTCAGGATTTTCTAACGATATGTATGAAAAAGAAG
GCGCTAAGATCGTAACTCACGAACAAGCATGGGAAGCTGATCTTGTTATCAAAGTAAAAGAACCTCATGAAAGCGAATAT
CAATATTTCAAAAAGAATCAAATTATCTGGGGATTTTTACATCTAGCATCTTCAAAAGAAATAGTAGAAAAAATGCAAGA
AGTTGGTGTAACTGCGATTAGTGGTGAAACCATTATAAAAAATGGAAAAGCAGAATTATTAGCGCCAATGAGTGCTATAG
CAGGTCAACGCTCAGCAATTATGGGAGCTTACTACTCTGAAGCACAACATGGTGGTCAAGGTACTTTAGTGACTGGTGTA
CATGAAAATGTGGATATACCTGGTAGTACATATGTGATTTTCGGTGGTGGAGTAGCAGCAACAAATGCAGCAAATGTTGC
CTTGGGACTAAATGCTAAAGTAATCATTATCGAGTTAAACGATGACCGCATTAAATATCTTGAAGATATGTATGCAGAAA
AAGATGTCACAGTAGTCAAATCAACACCAGAAAATTTAGCAGAACAAATTAAGAAAGCAGATGTATTTATTTCTACAATT
TTAATTCCAGGTGCGAAACCGCCAAAATTGGTTACTCGTGAGATGGTTAAATCAATGAAAAAAGGTTCAGTATTAATCGA
TATAGCTATTGACCAAGGTGGAACTATTGAAACAATTAGACCAACTACAATTTCTGATCCAGTGTATGAAGAAGAAGGTG
TGATTCATTATGGTGTACCAAATCAACCAGGAGCAGTCCCAAGAACTTCAACAATGGCATTAGCACAAGGAAATATTGAT
TATATATTAGAAATTTGTGACAAAGGCTTAGAACAAGCAATTAAAGATAATGAAGCCTTAAGTACTGGTGTAAACATTTA
CCAAGGACAAGTGACAAATCAAGGATTAGCTTCATCACATGACCTAGATTATAAAGAAATATTAAATGTTATCGAATAG

Upstream 100 bases:

>100_bases
TAGATAAAATATGAATAATTAATTAATGGTATTTACATATTCATAACCAAAGGATAAAATAATTGTGAAATTATTCACAA
ATGAAAGAGGAGTGTTGCAA

Downstream 100 bases:

>100_bases
ATAGTAATTTAAATGAAATTGAGTGAAATGAATATTTTAAATATAGCATTATAGTTTGGACTAAAAATTTACAAAACGGA
AGGATGTAATTATTATGACA

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE

Sequences:

>Translated_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
>Mature_372_residues
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEY
QYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNID
YILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family

Homologues:

Organism=Homo sapiens, GI122939155, Length=359, Percent_Identity=30.08356545961, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI122939153, Length=359, Percent_Identity=30.08356545961, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1787887, Length=352, Percent_Identity=29.5454545454545, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17550456, Length=346, Percent_Identity=30.0578034682081, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHA1_STAA3 (Q2FH00)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494028.1
- ProteinModelPortal:   Q2FH00
- SMR:   Q2FH00
- STRING:   Q2FH00
- EnsemblBacteria:   EBSTAT00000038007
- GeneID:   3914134
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1331
- eggNOG:   COG0686
- GeneTree:   EBGT00050000024386
- HOGENOM:   HBG289735
- OMA:   GAYYLEA
- ProtClustDB:   CLSK885351
- GO:   GO:0005488
- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141
- PIRSF:   PIRSF000183
- TIGRFAMs:   TIGR00518

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N

EC number: =1.4.1.1

Molecular weight: Translated: 40235; Mature: 40235

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00836 ALADH_PNT_1; PS00837 ALADH_PNT_2

Important sites: ACT_SITE 94-94

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEE
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHHC
>Mature Secondary Structure
MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTH
CHHHHHHHHHCCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCEEEEE
EQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIK
CCCCCCEEEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEE
NGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
TNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTI
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEE
LIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVP
EECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCC
NQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCCCC
DLDYKEILNVIE
CCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA