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The map label for this gene is patA [H]

Identifier: 57650243

GI number: 57650243

Start: 1064554

End: 1065708

Strand: Reverse

Name: patA [H]

Synonym: SACOL1058

Alternate gene names: 57650243

Gene position: 1065708-1064554 (Counterclockwise)

Preceding gene: 57650244

Following gene: 57650242

Centisome position: 37.93

GC content: 31.95

Gene sequence:

>1155_bases
ATGAAACTTTCTTTAAATTCTAATTCTAAATATTTAAGAGCACCAAGTATTCGCCAATTTTCAAATCGTATGAATAATTT
GGATGATTGTGTTAATTTAACTATTGGCCAACCAGACTTCCCGATGCCTGATGTTGTGAAAAAGGCATATATTGATGCTA
TTAACAATGACAAGACATCATACTCTCACAATAAAGGGTTATTAGAAACTCGCGAAGCAATTAGTCAATACTTCAAAAAT
CGTTATCATTTTTCCTATGATCCTGAAGAAATTATTGTGACAAATGGAGCAAGTGAAGCAATAGACACAACGTTACGTTC
TATCATAGAGCCTGGAGATGAAATTATAATACCGGGACCAATTTATGCAGGCTACATACCACTCATCGAAGTACTAGGTG
GTAAACCAATTTATATTGATACAACAGCAACACAATTTAAAATTACACCTGATGCATTAGAAAGTCATATTTCTCCAAAG
ACAAAAGCTGTCTTGTTAAATTATCCGACTAATCCAACTGGCGTAGTTTTAAAAAGAAATGAAGTTTTAAATATCGTAAA
TGTATTAAAAAAATATCCGTTATTTATTATTAGCGATGAGATTTATGCTGAAAATACATTTAGTGGTAAACATGTATCCT
TCGCTGAATTTGAAGACATTCGTGATCAATTAATATTAATTGGTGGTTTAAGTAAATCACACTCAGCAACCGGAATAAGA
ATTGGTTTTCTATTAGGACCTCAATATTTGATTGATAAATTAACATTTATGCACGCCTATAATTGTATTTGTGCCAATGT
TCCAGCTCAAATAGCATGTATAACAGCACTTAACGAAGGATTAGAAGCTCCTAAATATATGAACGAAGCTTATGTAGAAC
GAAGAAATTATTTAGTATCTGAATTAACTAAATTAGGTTTTGAGATTACCGCTCAACCTGAAGGCGCGTTTTATATTTTC
CCAAGTATTAAACATATCACCGATGACGATTTCGAATTTTGTGTCGATTTACTTGAATCAACACATTTAGCAATCGTTCC
AGGCTCATCCTTTACAGAATTCGGTAAAGGATTTGTAAGGATTTCCTATGCTTATGAAATGGATGTTTTAAAAGAAGGTA
TGAAGAGACTTGCTAAATATTTAAATACTAAATAA

Upstream 100 bases:

>100_bases
AGCTTAAGTAATTTACCCTTTTTTGCTTTAAAAGTATGTTATGATATTATTAATTTCTAAATTTTTAGACAATATTTGAT
TTATATTTGAGGTGTCACAA

Downstream 100 bases:

>100_bases
AAATGATATGTTGAACTGGACGTCGTGAACTAAATTCATAGTACGTTCAGTTTTTTATATTCTATAAGTTTTAAATAATA
CTCTATAGAGACTGTAAATA

Product: aminotransferase, class I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTSYSHNKGLLETREAISQYFKN
RYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPK
TKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPLFIISDEIYAENTFSGKHVSFAEFEDIRDQLILIGGLSKSHSATGIR
IGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIF
PSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK

Sequences:

>Translated_384_residues
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTSYSHNKGLLETREAISQYFKN
RYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPK
TKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPLFIISDEIYAENTFSGKHVSFAEFEDIRDQLILIGGLSKSHSATGIR
IGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIF
PSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK
>Mature_384_residues
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTSYSHNKGLLETREAISQYFKN
RYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPK
TKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPLFIISDEIYAENTFSGKHVSFAEFEDIRDQLILIGGLSKSHSATGIR
IGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIF
PSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=373, Percent_Identity=29.2225201072386, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI56713256, Length=373, Percent_Identity=29.2225201072386, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI95147551, Length=327, Percent_Identity=24.4648318042813, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI169881279, Length=327, Percent_Identity=24.4648318042813, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI169881281, Length=318, Percent_Identity=21.6981132075472, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4507369, Length=226, Percent_Identity=30.9734513274336, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19263340, Length=388, Percent_Identity=25.2577319587629, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI215599424, Length=388, Percent_Identity=25.2577319587629, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI149944424, Length=382, Percent_Identity=20.1570680628272, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4885351, Length=383, Percent_Identity=24.0208877284595, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=356, Percent_Identity=26.685393258427, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=27.1978021978022, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=27.1794871794872, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787710, Length=337, Percent_Identity=23.7388724035608, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787909, Length=364, Percent_Identity=22.5274725274725, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790797, Length=303, Percent_Identity=24.7524752475248, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=399, Percent_Identity=27.0676691729323, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=399, Percent_Identity=27.0676691729323, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=26.2626262626263, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=22.911051212938, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=380, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=298, Percent_Identity=30.2013422818792, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=392, Percent_Identity=27.2959183673469, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320317, Length=377, Percent_Identity=26.525198938992, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.4845360824742, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.4845360824742, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.4845360824742, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.4845360824742, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI18859735, Length=408, Percent_Identity=23.2843137254902, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=24.8101265822785, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43147; Mature: 43147

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTS
CEEECCCCCCEEECCCHHHHHHHHCCHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCCCC
YSHNKGLLETREAISQYFKNRYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGP
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEECCC
IYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPKTKAVLLNYPTNPTGVVLKRN
HHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHHHCCCCCCEEEEEECCCCCCEEEEECH
EVLNIVNVLKKYPLFIISDEIYAENTFSGKHVSFAEFEDIRDQLILIGGLSKSHSATGIR
HHHHHHHHHHHCCEEEEECHHEECCCCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCCEE
IGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVS
EEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTKLGFEITAQPEGAFYIFPSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVR
HHHHCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHCCCEEE
ISYAYEMDVLKEGMKRLAKYLNTK
EEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTS
CEEECCCCCCEEECCCHHHHHHHHCCHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCCCC
YSHNKGLLETREAISQYFKNRYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGP
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEECCC
IYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPKTKAVLLNYPTNPTGVVLKRN
HHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHHHCCCCCCEEEEEECCCCCCEEEEECH
EVLNIVNVLKKYPLFIISDEIYAENTFSGKHVSFAEFEDIRDQLILIGGLSKSHSATGIR
HHHHHHHHHHHCCEEEEECHHEECCCCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCCEE
IGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVS
EEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTKLGFEITAQPEGAFYIFPSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVR
HHHHCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHCCCEEE
ISYAYEMDVLKEGMKRLAKYLNTK
EEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]